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• W2801062308 abstract "Sulfur dioxide (SO2), as one of the most dangerous atmospheric pollutants, is associated with several respiratory and neurological diseases. Meanwhile, lysosomes, as scavenger of living cells, play a pivotal role in the metabolic process. However, the pathologic mechanisms of sulfur dioxide at the subcellular level remain elusive in part due to the lack of methods for detecting of SO2 in the organelles. Accordingly, the study of SO2 in lysosome is of high interest. Herein, a two-photon fluorescence probe (Na-SO2-Lyso) for detecting of SO2 derivatives was developed based on a unique CN isomerization mechanism. The probe Na-SO2-Lyso could respond to SO2 rapidly in less than 15 s with excellent sensitivity. Significantly, Na-SO2-Lyso was effectively applied to image of SO2 in lysosomes of living cells for the first time. Moreover, Na-SO2-Lyso also can be used for detecting of SO2 derivatives in living zebrafish." @default.
• W2801062308 created "2018-05-17" @default.
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• W2801062308 date "2018-09-01" @default.
• W2801062308 modified "2023-10-16" @default.
• W2801062308 title "A lysosome-targeted two-photon fluorescence probe for imaging of sulfur dioxide derivatives in living cells and zebrafish" @default.
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• W2801062308 doi "https://doi.org/10.1016/j.snb.2018.04.069" @default.
• W2801062308 hasPublicationYear "2018" @default.
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