FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801136175> ?p ?o ?g. }

• W2801136175 endingPage "e226" @default.
• W2801136175 startingPage "e221" @default.
• W2801136175 abstract "Background: A clinically meaningful impairment of bone mass secondary to malabsorption is frequent in untreated celiac disease. In adult patients, a rigorous gluten-free diet (GFD) significantly improves, but does not always normalize, bone mineral density (BMD). The reason for this marginal response is unclear. Accordingly, we evaluated the role of both local and systemic factors for bone loss in celiac patients on long-term GFD. Study: In a prospective cohort, 22 patients with low lumbar and/or femoral BMD and 22 with normal BMD underwent bone and mineral metabolism evaluation: we tested calcium, phosphate, parathyroid hormone, and vitamin D; telopeptide of type I collagen, a bone resorption index; propeptide of type I procollagen, a bone neoformation index; receptor antagonist of NF-kB ligand, an osteoclast-stimulating factor; osteoprotegerin (OPG), a decoy receptor for RANKL. Sunlight exposure and physical exercise were measured. Results: Patients with bone loss showed prevalently osteopenia, severe osteoporosis was rare. In comparison with normal BMD patients, they showed higher serum OPG, telopeptide, and lower serum propeptide, suggesting an increased bone turnover. Lumbar T -score was negatively correlated with OPG, telopeptide and RANKL and positively with propeptide. Propeptide was negatively correlated with OPG and telopeptide. OPG was positively correlated with telopeptide. Conclusions: The persistent activation of inflammation should be considered the main pathophysiological mechanism for bone defect in celiac disease patients with bone loss on long-term GFD. High levels of OPG, an attempt at protective mechanism, and low levels of propeptide of type I procollagen, reflecting an insufficient matrix production, characterize this subgroup of patients." @default.
• W2801136175 created "2018-05-17" @default.
• W2801136175 creator A5003488307 @default.
• W2801136175 creator A5005545503 @default.
• W2801136175 creator A5031117940 @default.
• W2801136175 creator A5049800927 @default.
• W2801136175 creator A5055022644 @default.
• W2801136175 creator A5068956446 @default.
• W2801136175 creator A5073143722 @default.
• W2801136175 creator A5078084787 @default.
• W2801136175 creator A5085146789 @default.
• W2801136175 creator A5087011970 @default.
• W2801136175 creator A5088008401 @default.
• W2801136175 date "2019-07-01" @default.
• W2801136175 modified "2023-10-18" @default.
• W2801136175 title "Alterations of Inflammatory and Matrix Production Indices in Celiac Disease With Low Bone Mass on Long-term Gluten-free Diet" @default.
• W2801136175 cites W1964854805 @default.
• W2801136175 cites W1972354494 @default.
• W2801136175 cites W1972880322 @default.
• W2801136175 cites W1977114282 @default.
• W2801136175 cites W2001745097 @default.
• W2801136175 cites W2008717439 @default.
• W2801136175 cites W2022638195 @default.
• W2801136175 cites W2025709853 @default.
• W2801136175 cites W2029005518 @default.
• W2801136175 cites W2030936317 @default.
• W2801136175 cites W2036279688 @default.
• W2801136175 cites W2050546561 @default.
• W2801136175 cites W2051177437 @default.
• W2801136175 cites W2061097390 @default.
• W2801136175 cites W2067419903 @default.
• W2801136175 cites W2076331472 @default.
• W2801136175 cites W2076693807 @default.
• W2801136175 cites W2077356183 @default.
• W2801136175 cites W2083665919 @default.
• W2801136175 cites W2087484885 @default.
• W2801136175 cites W2092065668 @default.
• W2801136175 cites W2102991809 @default.
• W2801136175 cites W2106392301 @default.
• W2801136175 cites W2117517579 @default.
• W2801136175 cites W2144329636 @default.
• W2801136175 cites W2144756507 @default.
• W2801136175 cites W2160841203 @default.
• W2801136175 cites W2167685968 @default.
• W2801136175 doi "https://doi.org/10.1097/mcg.0000000000001032" @default.
• W2801136175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29672438" @default.
• W2801136175 hasPublicationYear "2019" @default.
• W2801136175 type Work @default.
• W2801136175 sameAs 2801136175 @default.
• W2801136175 citedByCount "12" @default.
• W2801136175 countsByYear W28011361752019 @default.
• W2801136175 countsByYear W28011361752020 @default.
• W2801136175 countsByYear W28011361752021 @default.
• W2801136175 countsByYear W28011361752022 @default.
• W2801136175 countsByYear W28011361752023 @default.
• W2801136175 crossrefType "journal-article" @default.
• W2801136175 hasAuthorship W2801136175A5003488307 @default.
• W2801136175 hasAuthorship W2801136175A5005545503 @default.
• W2801136175 hasAuthorship W2801136175A5031117940 @default.
• W2801136175 hasAuthorship W2801136175A5049800927 @default.
• W2801136175 hasAuthorship W2801136175A5055022644 @default.
• W2801136175 hasAuthorship W2801136175A5068956446 @default.
• W2801136175 hasAuthorship W2801136175A5073143722 @default.
• W2801136175 hasAuthorship W2801136175A5078084787 @default.
• W2801136175 hasAuthorship W2801136175A5085146789 @default.
• W2801136175 hasAuthorship W2801136175A5087011970 @default.
• W2801136175 hasAuthorship W2801136175A5088008401 @default.
• W2801136175 hasConcept C125870589 @default.
• W2801136175 hasConcept C126322002 @default.
• W2801136175 hasConcept C131075544 @default.
• W2801136175 hasConcept C134018914 @default.
• W2801136175 hasConcept C160160445 @default.
• W2801136175 hasConcept C170033053 @default.
• W2801136175 hasConcept C170493617 @default.
• W2801136175 hasConcept C181199279 @default.
• W2801136175 hasConcept C185592680 @default.
• W2801136175 hasConcept C2776541429 @default.
• W2801136175 hasConcept C2776886416 @default.
• W2801136175 hasConcept C2777083390 @default.
• W2801136175 hasConcept C2780426850 @default.
• W2801136175 hasConcept C2781208988 @default.
• W2801136175 hasConcept C519063684 @default.
• W2801136175 hasConcept C55493867 @default.
• W2801136175 hasConcept C673006 @default.
• W2801136175 hasConcept C71924100 @default.
• W2801136175 hasConcept C88045685 @default.
• W2801136175 hasConceptScore W2801136175C125870589 @default.
• W2801136175 hasConceptScore W2801136175C126322002 @default.
• W2801136175 hasConceptScore W2801136175C131075544 @default.
• W2801136175 hasConceptScore W2801136175C134018914 @default.
• W2801136175 hasConceptScore W2801136175C160160445 @default.
• W2801136175 hasConceptScore W2801136175C170033053 @default.
• W2801136175 hasConceptScore W2801136175C170493617 @default.
• W2801136175 hasConceptScore W2801136175C181199279 @default.
• W2801136175 hasConceptScore W2801136175C185592680 @default.
• W2801136175 hasConceptScore W2801136175C2776541429 @default.
• W2801136175 hasConceptScore W2801136175C2776886416 @default.
• W2801136175 hasConceptScore W2801136175C2777083390 @default.

• next