Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801166706> ?p ?o ?g. }
- W2801166706 endingPage "122" @default.
- W2801166706 startingPage "107" @default.
- W2801166706 abstract "Snakebite envenoming represents a major issue in rural areas of tropical and subtropical regions across sub-Saharan Africa, South to Southeast Asia, Latin America and Oceania. Antivenoms constitute the only scientifically validated therapy for snakebite envenomings, provided they are safe, effective, affordable, accessible and administered appropriately. However, the lack of financial incentives in a technology that has remained relatively unchanged for more than a century, has contributed to some manufacturers leaving the market and others downscaling production or increasing the prices, leading to a decline in the availability and accessibility for these life-saving antidotes to millions of rural poor most at risk from snakebites in low income countries. The shortage of antivenoms can be significantly alleviated by optimizing the use of current antivenoms (through the assessment of their specific and paraspecific efficacy against the different medically relevant homologous and heterologous snake venoms) and by generating novel polyspecific antivenoms exhibiting broad clinical spectrum and wide geographic distribution range. Research on venoms has been continuously enhanced by advances in technology. Particularly, the last decade has witnessed the development of omics strategies for unravelling the toxin composition of venoms (“venomics”) and to assess the immunorecognition profile of antivenoms (“antivenomics”). Here, we review recent developments and reflect on near future innovations that promise to revolutionize the mutually enlightening relationship between evolutionary and translational venomics." @default.
- W2801166706 created "2018-05-17" @default.
- W2801166706 creator A5028290411 @default.
- W2801166706 creator A5055816232 @default.
- W2801166706 creator A5077807874 @default.
- W2801166706 creator A5081491247 @default.
- W2801166706 date "2018-06-01" @default.
- W2801166706 modified "2023-10-14" @default.
- W2801166706 title "Toxin-resolved antivenomics-guided assessment of the immunorecognition landscape of antivenoms" @default.
- W2801166706 cites W1819759213 @default.
- W2801166706 cites W1867204799 @default.
- W2801166706 cites W1885530637 @default.
- W2801166706 cites W1904034280 @default.
- W2801166706 cites W1965190825 @default.
- W2801166706 cites W1965734525 @default.
- W2801166706 cites W1969795707 @default.
- W2801166706 cites W1970696723 @default.
- W2801166706 cites W1973563015 @default.
- W2801166706 cites W1975509769 @default.
- W2801166706 cites W1978756454 @default.
- W2801166706 cites W1980387413 @default.
- W2801166706 cites W1982411844 @default.
- W2801166706 cites W1988946293 @default.
- W2801166706 cites W1991257079 @default.
- W2801166706 cites W1994600768 @default.
- W2801166706 cites W1995571414 @default.
- W2801166706 cites W1997504014 @default.
- W2801166706 cites W2001386727 @default.
- W2801166706 cites W2001670682 @default.
- W2801166706 cites W2002075122 @default.
- W2801166706 cites W2003557975 @default.
- W2801166706 cites W2004976464 @default.
- W2801166706 cites W2010012196 @default.
- W2801166706 cites W2011061591 @default.
- W2801166706 cites W2013622729 @default.
- W2801166706 cites W2014928855 @default.
- W2801166706 cites W2015349300 @default.
- W2801166706 cites W2015718953 @default.
- W2801166706 cites W2018897047 @default.
- W2801166706 cites W2020732669 @default.
- W2801166706 cites W2024519151 @default.
- W2801166706 cites W2027259074 @default.
- W2801166706 cites W2028285527 @default.
- W2801166706 cites W2030237382 @default.
- W2801166706 cites W2031952431 @default.
- W2801166706 cites W2042987909 @default.
- W2801166706 cites W2043896568 @default.
- W2801166706 cites W2044750939 @default.
- W2801166706 cites W2051583331 @default.
- W2801166706 cites W2056544257 @default.
- W2801166706 cites W2069816601 @default.
- W2801166706 cites W2069882002 @default.
- W2801166706 cites W2072810823 @default.
- W2801166706 cites W2075826307 @default.
- W2801166706 cites W2076807510 @default.
- W2801166706 cites W2078283347 @default.
- W2801166706 cites W2079881546 @default.
- W2801166706 cites W2086332380 @default.
- W2801166706 cites W2088697979 @default.
- W2801166706 cites W2089813874 @default.
- W2801166706 cites W2090853097 @default.
- W2801166706 cites W2091041722 @default.
- W2801166706 cites W2092745850 @default.
- W2801166706 cites W2101124187 @default.
- W2801166706 cites W2101857546 @default.
- W2801166706 cites W210522119 @default.
- W2801166706 cites W2109032445 @default.
- W2801166706 cites W2110632707 @default.
- W2801166706 cites W2111975429 @default.
- W2801166706 cites W2113970066 @default.
- W2801166706 cites W2117327695 @default.
- W2801166706 cites W2129754968 @default.
- W2801166706 cites W2143162691 @default.
- W2801166706 cites W2151368344 @default.
- W2801166706 cites W2153550313 @default.
- W2801166706 cites W2155553629 @default.
- W2801166706 cites W2160110467 @default.
- W2801166706 cites W2161345806 @default.
- W2801166706 cites W2163754385 @default.
- W2801166706 cites W2166647530 @default.
- W2801166706 cites W2168302286 @default.
- W2801166706 cites W2216526400 @default.
- W2801166706 cites W2217088963 @default.
- W2801166706 cites W2218997565 @default.
- W2801166706 cites W2229266328 @default.
- W2801166706 cites W2238964987 @default.
- W2801166706 cites W2257846005 @default.
- W2801166706 cites W2279440973 @default.
- W2801166706 cites W2287622873 @default.
- W2801166706 cites W2290466312 @default.
- W2801166706 cites W2308212135 @default.
- W2801166706 cites W2315025742 @default.
- W2801166706 cites W2326188727 @default.
- W2801166706 cites W2378145088 @default.
- W2801166706 cites W2397071648 @default.
- W2801166706 cites W2412311868 @default.
- W2801166706 cites W2417578947 @default.
- W2801166706 cites W2424235995 @default.