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- W2801254818 abstract "Summary Differential expression of HLA ‐ DQA 1 and HLA ‐ DQB 1 gene alleles was analysed in three different cell populations isolated from peripheral blood—B lymphocytes, monocytes and whole‐blood cells. Interallelic differences in mRNA levels were observed: DQA 1*03 alleles were among the most expressed in all cell types, whereas DQA 1*05 alleles were least expressed in whole blood and monocytes and among the most expressed in B cells. For DQB 1 gene, DQB 1*06 group of alleles were the most expressed, and DQB 1*02 group the least expressed within all cell populations examined. In comparison with the rest alleles, DQB 1*06 and DQB 1*05:02 alleles have higher expression in monocytes than in B cells, professional antigen‐presenting cells. Cell type‐specific regulation of expression was observed as well, with higher and more balanced expression of alleles in B lymphocytes compared to monocytes." @default.
- W2801254818 created "2018-05-17" @default.
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- W2801254818 date "2018-04-16" @default.
- W2801254818 modified "2023-10-18" @default.
- W2801254818 title "Expression of <scp>HLA</scp>‐<scp>DQA</scp>1 and <scp>HLA</scp>‐<scp>DQB</scp>1 genes in B lymphocytes, monocytes and whole blood" @default.
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- W2801254818 doi "https://doi.org/10.1111/iji.12367" @default.
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