Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801288128> ?p ?o ?g. }
- W2801288128 endingPage "e0198362" @default.
- W2801288128 startingPage "e0198362" @default.
- W2801288128 abstract "Octopamine regulates feeding behavioral responses in Drosophila melanogaster, however the molecular and circuit mechanisms have not been fully elucidated. Here, we investigated the role of a subset of octopaminergic neurons, the OA-VPM4 cluster, in sucrose acceptance behavior. Thermogenetic activation of Gal4 lines containing OA-VPM4 promoted proboscis extension to sucrose, while optogenetic inactivation reduced extension. Anatomically, the presynaptic terminals of OA-VPM4 are in close proximity to the axons of sugar-responsive gustatory sensory neurons. Moreover, RNAi knockdown of a specific class of octopamine receptor, OAMB, selectively in sugar-sensing gustatory neurons decreased the behavioral response to sucrose. By calcium imaging experiments, we found that application of octopamine potentiates sensory responses to sucrose in satiated flies. Taken together, these findings suggest a model by which OA-VPM4 promotes feeding behavior by modulating the activity of sensory neurons." @default.
- W2801288128 created "2018-05-17" @default.
- W2801288128 creator A5000276142 @default.
- W2801288128 creator A5005677803 @default.
- W2801288128 creator A5010181692 @default.
- W2801288128 creator A5040128728 @default.
- W2801288128 date "2018-06-27" @default.
- W2801288128 modified "2023-10-18" @default.
- W2801288128 title "A subset of octopaminergic neurons that promotes feeding initiation in Drosophila melanogaster" @default.
- W2801288128 cites W1534263444 @default.
- W2801288128 cites W1652929228 @default.
- W2801288128 cites W1689177678 @default.
- W2801288128 cites W1788106766 @default.
- W2801288128 cites W1820925839 @default.
- W2801288128 cites W1876068674 @default.
- W2801288128 cites W1968358311 @default.
- W2801288128 cites W1969645371 @default.
- W2801288128 cites W1972569657 @default.
- W2801288128 cites W1972769562 @default.
- W2801288128 cites W1977146259 @default.
- W2801288128 cites W1981615520 @default.
- W2801288128 cites W1981922832 @default.
- W2801288128 cites W1982980578 @default.
- W2801288128 cites W1984841747 @default.
- W2801288128 cites W1985346521 @default.
- W2801288128 cites W1986562178 @default.
- W2801288128 cites W1986574990 @default.
- W2801288128 cites W1992509769 @default.
- W2801288128 cites W1994253350 @default.
- W2801288128 cites W1997543121 @default.
- W2801288128 cites W1997917204 @default.
- W2801288128 cites W2002445028 @default.
- W2801288128 cites W2006229889 @default.
- W2801288128 cites W2012592260 @default.
- W2801288128 cites W2028791709 @default.
- W2801288128 cites W2034348439 @default.
- W2801288128 cites W2037366394 @default.
- W2801288128 cites W2039528431 @default.
- W2801288128 cites W2041851452 @default.
- W2801288128 cites W2043760958 @default.
- W2801288128 cites W2044009218 @default.
- W2801288128 cites W2044501583 @default.
- W2801288128 cites W2050930166 @default.
- W2801288128 cites W2058665312 @default.
- W2801288128 cites W2063834599 @default.
- W2801288128 cites W2064813979 @default.
- W2801288128 cites W2080530437 @default.
- W2801288128 cites W2084225775 @default.
- W2801288128 cites W2092188047 @default.
- W2801288128 cites W2093534366 @default.
- W2801288128 cites W2099284593 @default.
- W2801288128 cites W2106789000 @default.
- W2801288128 cites W2108489599 @default.
- W2801288128 cites W2108751101 @default.
- W2801288128 cites W2113394141 @default.
- W2801288128 cites W2117794907 @default.
- W2801288128 cites W2118398316 @default.
- W2801288128 cites W2137646439 @default.
- W2801288128 cites W2141830087 @default.
- W2801288128 cites W2148631122 @default.
- W2801288128 cites W2148890902 @default.
- W2801288128 cites W2159782501 @default.
- W2801288128 cites W2171332611 @default.
- W2801288128 cites W2318968105 @default.
- W2801288128 cites W2461651725 @default.
- W2801288128 cites W2528832300 @default.
- W2801288128 cites W2580319655 @default.
- W2801288128 cites W2588896198 @default.
- W2801288128 cites W4321318449 @default.
- W2801288128 doi "https://doi.org/10.1371/journal.pone.0198362" @default.
- W2801288128 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6021039" @default.
- W2801288128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29949586" @default.
- W2801288128 hasPublicationYear "2018" @default.
- W2801288128 type Work @default.
- W2801288128 sameAs 2801288128 @default.
- W2801288128 citedByCount "36" @default.
- W2801288128 countsByYear W28012881282018 @default.
- W2801288128 countsByYear W28012881282019 @default.
- W2801288128 countsByYear W28012881282020 @default.
- W2801288128 countsByYear W28012881282021 @default.
- W2801288128 countsByYear W28012881282022 @default.
- W2801288128 countsByYear W28012881282023 @default.
- W2801288128 crossrefType "journal-article" @default.
- W2801288128 hasAuthorship W2801288128A5000276142 @default.
- W2801288128 hasAuthorship W2801288128A5005677803 @default.
- W2801288128 hasAuthorship W2801288128A5010181692 @default.
- W2801288128 hasAuthorship W2801288128A5040128728 @default.
- W2801288128 hasBestOaLocation W28012881281 @default.
- W2801288128 hasConcept C104317684 @default.
- W2801288128 hasConcept C126322002 @default.
- W2801288128 hasConcept C169760540 @default.
- W2801288128 hasConcept C170493617 @default.
- W2801288128 hasConcept C2775864247 @default.
- W2801288128 hasConcept C2776032975 @default.
- W2801288128 hasConcept C2780104201 @default.
- W2801288128 hasConcept C2780696224 @default.
- W2801288128 hasConcept C50738837 @default.
- W2801288128 hasConcept C519063684 @default.