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- W2801296097 abstract "Acute intermittent hypoxia (AIH) enhances voluntary motor output in humans with central nervous system damage. The neural mechanisms contributing to these beneficial effects are unknown. We examined corticospinal function by evaluating motor evoked potentials (MEPs) elicited by cortical and subcortical stimulation of corticospinal axons and the activity in intracortical circuits in a finger muscle before and after 30 min of AIH or sham AIH. We found that the amplitude of cortically and subcortically elicited MEPs increased for 75 min after AIH but not sham AIH while intracortical activity remained unchanged. To examine further these subcortical effects, we assessed spike-timing dependent plasticity (STDP) targeting spinal synapses and the excitability of spinal motoneurons. Notably, AIH increased STDP outcomes while spinal motoneuron excitability remained unchanged. Our results provide the first evidence that AIH changes corticospinal function in humans, likely by altering corticospinal-motoneuronal synaptic transmission. AIH may represent a novel noninvasive approach for inducing spinal plasticity in humans." @default.
- W2801296097 created "2018-05-17" @default.
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- W2801296097 date "2018-04-24" @default.
- W2801296097 modified "2023-10-16" @default.
- W2801296097 title "Acute intermittent hypoxia enhances corticospinal synaptic plasticity in humans" @default.
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- W2801296097 cites W1966688219 @default.
- W2801296097 cites W1967142320 @default.
- W2801296097 cites W1968429176 @default.
- W2801296097 cites W1968467551 @default.
- W2801296097 cites W1969091342 @default.
- W2801296097 cites W1970971137 @default.
- W2801296097 cites W1972399504 @default.
- W2801296097 cites W1975080955 @default.
- W2801296097 cites W1975444758 @default.
- W2801296097 cites W1978873677 @default.
- W2801296097 cites W1981358508 @default.
- W2801296097 cites W1981948679 @default.
- W2801296097 cites W1990470025 @default.
- W2801296097 cites W1993905764 @default.
- W2801296097 cites W1997619327 @default.
- W2801296097 cites W1999399172 @default.
- W2801296097 cites W2009859845 @default.
- W2801296097 cites W2011135037 @default.
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- W2801296097 cites W2033337525 @default.
- W2801296097 cites W2034226385 @default.
- W2801296097 cites W2040298453 @default.
- W2801296097 cites W2043111033 @default.
- W2801296097 cites W2046456623 @default.
- W2801296097 cites W2049512910 @default.
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- W2801296097 doi "https://doi.org/10.7554/elife.34304" @default.
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- W2801296097 hasPublicationYear "2018" @default.
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