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- W2801297536 abstract "5-Oxopiperazine-2-carboxamides and respective carboxylic acids (obtained by the Castagnoli–Cushman reaction of protected iminodiacetic anhydride) were converted into cis- and trans-configured bicyclic piperazines containing two stereogenic centers. The latter are not only well-established mimetics of peptide β-turn but also attractive, high-Fsp3 cores for drug design in general. The methodology was applied to the preparation of ring-expanded version of bicyclic piperazines not described in the literature." @default.
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- W2801297536 date "2018-04-27" @default.
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- W2801297536 title "Bicyclic Piperazine Mimetics of the Peptide β-Turn Assembled via the Castagnoli–Cushman Reaction" @default.
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- W2801297536 doi "https://doi.org/10.1021/acs.joc.8b00811" @default.
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