Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801298049> ?p ?o ?g. }
- W2801298049 endingPage "2188" @default.
- W2801298049 startingPage "2179" @default.
- W2801298049 abstract "Recently, many immunosuppressive checkpoints such as PD-L1, CTLA-4 and CD47, were identified in succession and serve as potential immunotherapy targets in human cancers. Among them, CD47, a 'marker-of-self' protein that is overexpressed broadly across tumor types, is emerging as a novel potent macrophage immune checkpoint for cancer immunotherapy. In this review, we highlight the prominent role of CD47 as a 'don't-eat-me' signal that inhibits macrophage phagocytosis for immune evasion of a tumor and presents the opportunities and challenges for CD47 inhibitors both as monotherapy and in combination treatments for hematological cancers and solid tumors; some of these agents are currently in clinical trials." @default.
- W2801298049 created "2018-05-17" @default.
- W2801298049 creator A5043365458 @default.
- W2801298049 creator A5091455947 @default.
- W2801298049 date "2018-09-01" @default.
- W2801298049 modified "2023-09-25" @default.
- W2801298049 title "CD47 is a novel potent immunotherapy target in human malignancies: current studies and future promises" @default.
- W2801298049 cites W1497770306 @default.
- W2801298049 cites W1519861330 @default.
- W2801298049 cites W1587414944 @default.
- W2801298049 cites W1907947122 @default.
- W2801298049 cites W1964757399 @default.
- W2801298049 cites W1974752555 @default.
- W2801298049 cites W1988258153 @default.
- W2801298049 cites W1996760725 @default.
- W2801298049 cites W2007987850 @default.
- W2801298049 cites W2011076421 @default.
- W2801298049 cites W2040062469 @default.
- W2801298049 cites W2040787108 @default.
- W2801298049 cites W2045012199 @default.
- W2801298049 cites W2067114333 @default.
- W2801298049 cites W2068052762 @default.
- W2801298049 cites W2076781845 @default.
- W2801298049 cites W2082861282 @default.
- W2801298049 cites W2089881927 @default.
- W2801298049 cites W2103746815 @default.
- W2801298049 cites W2106545303 @default.
- W2801298049 cites W2107075226 @default.
- W2801298049 cites W2110882632 @default.
- W2801298049 cites W2127438212 @default.
- W2801298049 cites W2133346943 @default.
- W2801298049 cites W2134487724 @default.
- W2801298049 cites W2139418176 @default.
- W2801298049 cites W2145065085 @default.
- W2801298049 cites W2158298066 @default.
- W2801298049 cites W2169550645 @default.
- W2801298049 cites W2205886515 @default.
- W2801298049 cites W2277129094 @default.
- W2801298049 cites W2289935555 @default.
- W2801298049 cites W2295526061 @default.
- W2801298049 cites W2339658610 @default.
- W2801298049 cites W2341432578 @default.
- W2801298049 cites W2414840542 @default.
- W2801298049 cites W2473212158 @default.
- W2801298049 cites W2531440323 @default.
- W2801298049 cites W2550646651 @default.
- W2801298049 cites W2566871817 @default.
- W2801298049 cites W2590534615 @default.
- W2801298049 cites W2590692536 @default.
- W2801298049 cites W2592953803 @default.
- W2801298049 cites W2594014934 @default.
- W2801298049 cites W2596636194 @default.
- W2801298049 cites W2597064996 @default.
- W2801298049 cites W2603831404 @default.
- W2801298049 cites W2604193169 @default.
- W2801298049 cites W2610994169 @default.
- W2801298049 cites W2614438066 @default.
- W2801298049 cites W2619087203 @default.
- W2801298049 cites W2619738298 @default.
- W2801298049 cites W2625661423 @default.
- W2801298049 cites W2735553600 @default.
- W2801298049 cites W2753470570 @default.
- W2801298049 cites W2763960561 @default.
- W2801298049 cites W2765696340 @default.
- W2801298049 cites W4237810504 @default.
- W2801298049 doi "https://doi.org/10.2217/fon-2018-0035" @default.
- W2801298049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29667847" @default.
- W2801298049 hasPublicationYear "2018" @default.
- W2801298049 type Work @default.
- W2801298049 sameAs 2801298049 @default.
- W2801298049 citedByCount "39" @default.
- W2801298049 countsByYear W28012980492019 @default.
- W2801298049 countsByYear W28012980492020 @default.
- W2801298049 countsByYear W28012980492021 @default.
- W2801298049 countsByYear W28012980492022 @default.
- W2801298049 countsByYear W28012980492023 @default.
- W2801298049 crossrefType "journal-article" @default.
- W2801298049 hasAuthorship W2801298049A5043365458 @default.
- W2801298049 hasAuthorship W2801298049A5091455947 @default.
- W2801298049 hasConcept C121608353 @default.
- W2801298049 hasConcept C126322002 @default.
- W2801298049 hasConcept C202751555 @default.
- W2801298049 hasConcept C203014093 @default.
- W2801298049 hasConcept C2777701055 @default.
- W2801298049 hasConcept C2779244956 @default.
- W2801298049 hasConcept C2780030458 @default.
- W2801298049 hasConcept C2780104668 @default.
- W2801298049 hasConcept C2780674031 @default.
- W2801298049 hasConcept C2780851360 @default.
- W2801298049 hasConcept C2781433595 @default.
- W2801298049 hasConcept C502942594 @default.
- W2801298049 hasConcept C55493867 @default.
- W2801298049 hasConcept C71924100 @default.
- W2801298049 hasConcept C86803240 @default.
- W2801298049 hasConcept C8891405 @default.
- W2801298049 hasConceptScore W2801298049C121608353 @default.
- W2801298049 hasConceptScore W2801298049C126322002 @default.
- W2801298049 hasConceptScore W2801298049C202751555 @default.