Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801312009> ?p ?o ?g. }
- W2801312009 endingPage "240" @default.
- W2801312009 startingPage "229" @default.
- W2801312009 abstract "Granulocyte colony-stimulating factors (G-CSFs) decrease the incidence of febrile neutropenia (FN) in patients receiving myelosuppressive chemotherapy. This study examines the impact patient travel burden has on administration of prophylactic G-CSFs and the subsequent impact on FN incidence.Medicare claims data were used to identify a cohort of beneficiaries age 65+ with non-myeloid cancers at high risk for FN between January 2012 and December 2014. Driving distance and time were calculated from patient residence ZIP code to the location of G-CSF and/or chemotherapy administration. Regression models were used to estimate the odds of G-CSF prophylaxis relative to patient driving distance and time, and odds of FN incidence relative to timing of G-CSF administration (optimal [days 2-4 after chemotherapy], sub-optimal [same day], or none).The 52,389 study patients had a mean age of 73.5 years, and were 82% female and 89% white race; 49% had female breast cancer, 12% lung cancer, 15% ovarian cancer, and 24% non-Hodgkin's lymphoma. Of these high FN risk patients, 69% had at least one prophylactic G-CSF administration within at least one chemotherapy cycle. The percentage of patients receiving prophylactic G-CSFs in the first cycle was 56%. Median travel time was slightly longer for patients who did not receive G-CSFs and patients receiving short-acting vs long-acting G-CSFs. The odds of receiving no G-CSFs were 26-52% higher (depending on cancer type) for patients with a >80-min one-way travel time, compared to patients traveling <20-min. Concurrently, the odds of FN (using a narrow definition) were 18-93% higher for patients who did not receive G-CSFs in the first cycle of chemotherapy.Travel burden, linked to clinic visits for G-CSF administration following myelosuppressive chemotherapy, is associated with sub-optimal use of G-CSF prophylaxis, which may result in a higher incidence of FN." @default.
- W2801312009 created "2018-05-17" @default.
- W2801312009 creator A5023382490 @default.
- W2801312009 creator A5028608581 @default.
- W2801312009 creator A5058848268 @default.
- W2801312009 creator A5077100944 @default.
- W2801312009 date "2018-05-10" @default.
- W2801312009 modified "2023-10-18" @default.
- W2801312009 title "Risks and consequences of travel burden on prophylactic granulocyte colony-stimulating factor administration and incidence of febrile neutropenia in an aged Medicare population" @default.
- W2801312009 cites W1507633665 @default.
- W2801312009 cites W1529388857 @default.
- W2801312009 cites W1828514487 @default.
- W2801312009 cites W1963769796 @default.
- W2801312009 cites W1963900518 @default.
- W2801312009 cites W1971078174 @default.
- W2801312009 cites W1971639149 @default.
- W2801312009 cites W1987067274 @default.
- W2801312009 cites W2000792702 @default.
- W2801312009 cites W2000900335 @default.
- W2801312009 cites W2024933507 @default.
- W2801312009 cites W2036450045 @default.
- W2801312009 cites W2046463525 @default.
- W2801312009 cites W2057783437 @default.
- W2801312009 cites W2073543564 @default.
- W2801312009 cites W2076807083 @default.
- W2801312009 cites W2077781144 @default.
- W2801312009 cites W2081366131 @default.
- W2801312009 cites W2082276392 @default.
- W2801312009 cites W2083336892 @default.
- W2801312009 cites W2087926562 @default.
- W2801312009 cites W2090681697 @default.
- W2801312009 cites W2092700150 @default.
- W2801312009 cites W2098382233 @default.
- W2801312009 cites W2105550105 @default.
- W2801312009 cites W2113038656 @default.
- W2801312009 cites W2117366141 @default.
- W2801312009 cites W2120388840 @default.
- W2801312009 cites W2122658272 @default.
- W2801312009 cites W2124709079 @default.
- W2801312009 cites W2142195688 @default.
- W2801312009 cites W2145909848 @default.
- W2801312009 cites W2146249638 @default.
- W2801312009 cites W2146260047 @default.
- W2801312009 cites W2149955179 @default.
- W2801312009 cites W2150883028 @default.
- W2801312009 cites W2153791348 @default.
- W2801312009 cites W2157862701 @default.
- W2801312009 cites W2161107831 @default.
- W2801312009 cites W2175192019 @default.
- W2801312009 cites W2335359483 @default.
- W2801312009 cites W2341089058 @default.
- W2801312009 cites W2341557816 @default.
- W2801312009 cites W2610097533 @default.
- W2801312009 cites W2610397084 @default.
- W2801312009 cites W2737659130 @default.
- W2801312009 cites W389520367 @default.
- W2801312009 cites W4249759551 @default.
- W2801312009 doi "https://doi.org/10.1080/03007995.2018.1465906" @default.
- W2801312009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29661043" @default.
- W2801312009 hasPublicationYear "2018" @default.
- W2801312009 type Work @default.
- W2801312009 sameAs 2801312009 @default.
- W2801312009 citedByCount "4" @default.
- W2801312009 countsByYear W28013120092019 @default.
- W2801312009 countsByYear W28013120092020 @default.
- W2801312009 countsByYear W28013120092021 @default.
- W2801312009 countsByYear W28013120092023 @default.
- W2801312009 crossrefType "journal-article" @default.
- W2801312009 hasAuthorship W2801312009A5023382490 @default.
- W2801312009 hasAuthorship W2801312009A5028608581 @default.
- W2801312009 hasAuthorship W2801312009A5058848268 @default.
- W2801312009 hasAuthorship W2801312009A5077100944 @default.
- W2801312009 hasConcept C120665830 @default.
- W2801312009 hasConcept C121332964 @default.
- W2801312009 hasConcept C126322002 @default.
- W2801312009 hasConcept C141071460 @default.
- W2801312009 hasConcept C156957248 @default.
- W2801312009 hasConcept C2776694085 @default.
- W2801312009 hasConcept C2777063308 @default.
- W2801312009 hasConcept C2777767877 @default.
- W2801312009 hasConcept C2778658803 @default.
- W2801312009 hasConcept C2778850193 @default.
- W2801312009 hasConcept C2908647359 @default.
- W2801312009 hasConcept C61511704 @default.
- W2801312009 hasConcept C71924100 @default.
- W2801312009 hasConcept C99454951 @default.
- W2801312009 hasConceptScore W2801312009C120665830 @default.
- W2801312009 hasConceptScore W2801312009C121332964 @default.
- W2801312009 hasConceptScore W2801312009C126322002 @default.
- W2801312009 hasConceptScore W2801312009C141071460 @default.
- W2801312009 hasConceptScore W2801312009C156957248 @default.
- W2801312009 hasConceptScore W2801312009C2776694085 @default.
- W2801312009 hasConceptScore W2801312009C2777063308 @default.
- W2801312009 hasConceptScore W2801312009C2777767877 @default.
- W2801312009 hasConceptScore W2801312009C2778658803 @default.
- W2801312009 hasConceptScore W2801312009C2778850193 @default.
- W2801312009 hasConceptScore W2801312009C2908647359 @default.
- W2801312009 hasConceptScore W2801312009C61511704 @default.