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- W2801331459 endingPage "146" @default.
- W2801331459 startingPage "137" @default.
- W2801331459 abstract "The regulated alternations between wakefulness and sleep states reflect complex behavioral processes, orchestrated by distinct neurochemical changes in brain parenchyma. No single neurotransmitter or neuromodulator controls the sleep-wake states in isolation. Rather, fine-tuned interactions within organized neuronal circuits regulate waking and sleep states and drive their transitions. Structural or functional dysregulation and medications interfering with these ensembles can lead to sleep-wake disorders and exert wanted or unwanted pharmacological actions on sleep-wake states. Knowledge of the neurochemical bases of sleep-wake states, which will be discussed in this article, provides the conceptual framework for understanding pharmacological effects on sleep and wake." @default.
- W2801331459 created "2018-05-17" @default.
- W2801331459 creator A5039154815 @default.
- W2801331459 creator A5043449184 @default.
- W2801331459 date "2018-06-01" @default.
- W2801331459 modified "2023-10-12" @default.
- W2801331459 title "Sleep-Wake Neurochemistry" @default.
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- W2801331459 doi "https://doi.org/10.1016/j.jsmc.2018.03.002" @default.
- W2801331459 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29759265" @default.