Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801339976> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2801339976 endingPage "3083" @default.
- W2801339976 startingPage "3077" @default.
- W2801339976 abstract "BACKGROUND:This study aimed to evaluate the association of CD44 gene single-nucleotide polymorphisms with susceptibility to breast cancer. MATERIAL AND METHODS:This case-control study included 242 breast cancer patients and 252 normal people without disease. The single-nucleotide polymorphisms of the CD44 gene in the 2 groups were genotyped by PCR-LDR method. The OR and its 95% CI was calculated by chi-square test and logistic regression analysis. The construction of haplotypes and their interaction analysis with relevant factors were carried out by SHEsis and SNPStats online. RESULTS:The genotype distribution of CC and CT, CC and CC+CT, and CC+CT and TT in rs13347 showed a significant difference between cases and controls, and the difference in distribution of alleles C and T was statistically significant. The genotype and alleles distribution of rs4756195 and rs8193 showed no statistically significant difference (P>0.05). The haplotypes distribution of CAC, CGT, TAC, and TGT showed a significant difference between the 2 groups (P<0.05). The results of analysis of haplotypes and their interactions with relevant factors showed that breast cancer risk in the PR-negative group was significantly higher than that in the PR-positive group (P=0.016). We found an interaction between haplotypes and PR status. CONCLUSIONS:The genotypes CT, CT+TT, TT, and allele T in rs13347 may be risk factors for breast cancer. The haplotype CAC may be a protective factor against breast cancer, and CGT, TAC, and TGT may be risk factors for breast cancer. The PR status interacts with CD44 gene SNP." @default.
- W2801339976 created "2018-05-17" @default.
- W2801339976 creator A5024612938 @default.
- W2801339976 creator A5054054959 @default.
- W2801339976 creator A5070997690 @default.
- W2801339976 creator A5084250641 @default.
- W2801339976 date "2018-05-11" @default.
- W2801339976 modified "2023-09-26" @default.
- W2801339976 title "Association of Single-Nucleotide Polymorphisms of CD44 Gene with Susceptibility to Breast Cancer in Chinese Women" @default.
- W2801339976 cites W1565421491 @default.
- W2801339976 cites W1593442063 @default.
- W2801339976 cites W1788775001 @default.
- W2801339976 cites W1812133991 @default.
- W2801339976 cites W1966360257 @default.
- W2801339976 cites W1975358312 @default.
- W2801339976 cites W2054541267 @default.
- W2801339976 cites W2058430797 @default.
- W2801339976 cites W2065934262 @default.
- W2801339976 cites W2066761251 @default.
- W2801339976 cites W2069063266 @default.
- W2801339976 cites W2070462798 @default.
- W2801339976 cites W2088059979 @default.
- W2801339976 cites W2138842322 @default.
- W2801339976 cites W2139007882 @default.
- W2801339976 cites W2147575498 @default.
- W2801339976 cites W2297445915 @default.
- W2801339976 cites W2411419751 @default.
- W2801339976 cites W2560322684 @default.
- W2801339976 cites W384982486 @default.
- W2801339976 doi "https://doi.org/10.12659/msm.907422" @default.
- W2801339976 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5973502" @default.
- W2801339976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29748526" @default.
- W2801339976 hasPublicationYear "2018" @default.
- W2801339976 type Work @default.
- W2801339976 sameAs 2801339976 @default.
- W2801339976 citedByCount "6" @default.
- W2801339976 countsByYear W28013399762019 @default.
- W2801339976 countsByYear W28013399762021 @default.
- W2801339976 countsByYear W28013399762022 @default.
- W2801339976 crossrefType "journal-article" @default.
- W2801339976 hasAuthorship W2801339976A5024612938 @default.
- W2801339976 hasAuthorship W2801339976A5054054959 @default.
- W2801339976 hasAuthorship W2801339976A5070997690 @default.
- W2801339976 hasAuthorship W2801339976A5084250641 @default.
- W2801339976 hasBestOaLocation W28013399762 @default.
- W2801339976 hasConcept C104317684 @default.
- W2801339976 hasConcept C121608353 @default.
- W2801339976 hasConcept C126322002 @default.
- W2801339976 hasConcept C135763542 @default.
- W2801339976 hasConcept C143998085 @default.
- W2801339976 hasConcept C146304588 @default.
- W2801339976 hasConcept C151956035 @default.
- W2801339976 hasConcept C153209595 @default.
- W2801339976 hasConcept C180754005 @default.
- W2801339976 hasConcept C197754878 @default.
- W2801339976 hasConcept C530470458 @default.
- W2801339976 hasConcept C54355233 @default.
- W2801339976 hasConcept C71924100 @default.
- W2801339976 hasConcept C86803240 @default.
- W2801339976 hasConcept C90924648 @default.
- W2801339976 hasConceptScore W2801339976C104317684 @default.
- W2801339976 hasConceptScore W2801339976C121608353 @default.
- W2801339976 hasConceptScore W2801339976C126322002 @default.
- W2801339976 hasConceptScore W2801339976C135763542 @default.
- W2801339976 hasConceptScore W2801339976C143998085 @default.
- W2801339976 hasConceptScore W2801339976C146304588 @default.
- W2801339976 hasConceptScore W2801339976C151956035 @default.
- W2801339976 hasConceptScore W2801339976C153209595 @default.
- W2801339976 hasConceptScore W2801339976C180754005 @default.
- W2801339976 hasConceptScore W2801339976C197754878 @default.
- W2801339976 hasConceptScore W2801339976C530470458 @default.
- W2801339976 hasConceptScore W2801339976C54355233 @default.
- W2801339976 hasConceptScore W2801339976C71924100 @default.
- W2801339976 hasConceptScore W2801339976C86803240 @default.
- W2801339976 hasConceptScore W2801339976C90924648 @default.
- W2801339976 hasLocation W28013399761 @default.
- W2801339976 hasLocation W28013399762 @default.
- W2801339976 hasLocation W28013399763 @default.
- W2801339976 hasLocation W28013399764 @default.
- W2801339976 hasOpenAccess W2801339976 @default.
- W2801339976 hasPrimaryLocation W28013399761 @default.
- W2801339976 hasRelatedWork W1966708416 @default.
- W2801339976 hasRelatedWork W1982749768 @default.
- W2801339976 hasRelatedWork W2003614689 @default.
- W2801339976 hasRelatedWork W2030904903 @default.
- W2801339976 hasRelatedWork W2038017527 @default.
- W2801339976 hasRelatedWork W2050778956 @default.
- W2801339976 hasRelatedWork W2119763855 @default.
- W2801339976 hasRelatedWork W2327017833 @default.
- W2801339976 hasRelatedWork W2377221997 @default.
- W2801339976 hasRelatedWork W4242979853 @default.
- W2801339976 hasVolume "24" @default.
- W2801339976 isParatext "false" @default.
- W2801339976 isRetracted "false" @default.
- W2801339976 magId "2801339976" @default.
- W2801339976 workType "article" @default.