FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801375319> ?p ?o ?g. }

• W2801375319 endingPage "48" @default.
• W2801375319 startingPage "35" @default.
• W2801375319 abstract "Candida species are among the top 10 pathogens causing bloodstream infections associated with high morbidity, mortality. In spite of the development of new antifungal drugs, epidemiological studies have shown that resistance to antifungal drugs among Candida isolates is becoming a serious problem. The aim of this study was to compare the antifungal broth microdilution methods of the Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) for amphotericin B, fluconazole, itraconazole, voriconazole, posaconazole and anidulafungin susceptibility of Candida blood isolates. The study consisted of 74 Candida albicans, 67 Candida parapsilosis, 30 Candida glabrata, and 18 Candida tropicalis isolates. The minimum inhibitory concentrations were determined after 24 and 48 hour of incubation with CLSI method and only 24 hour of incubation with EUCAST method except anidulofungin. The MIC values obtained by both methods were considered to be compatible within ± 2 dilution limits. The categorical agreement between methods for each antifungal agent was assessed using clinical break points and epidemiological cut-off values. The agreement (± 2 dilution) between the methods was found to be species, drug, and incubation time dependent. After 24 hour incubation, good agreement category (> 90%) was detected between amphotericin B, itraconazole, posaconazole and anidulofungin, but was lower category (< 85%) was determined with fluconazole and voriconazole especially for relatively slow growing C.glabrata and C.parapsilosis isolates. Excellent categorical agreement (100%) was observed for amfoterisin B/C.parapsilosis, C.glabrata, C.tropicalis and anidulofungin/C.albicans, C.glabrata, C.tropicalis but least category was determined for posaconazole and C.albicans (71.6% at 24 hour; 73% at 48 hour). In vitro resistance of therapeutically used fluconazole and anidulafungin determined by both methods was rare among C.albicans (1.3%, 2.7% respectively), C.glabrata (0%, 3.3% respectively) and C.tropicalis (0%, 5.6% respectively) isolates but, an increase of non-susceptible isolates were observed among C.parapsilosis (11.9% at 24 hour of incubation; 17.9% at 48 hour of incubation) for fluconazole. There was also a cross resistance between fluconazole and voriconazole for three C.parapsilosis isolates and one multidrug resistant (fluconazole, itraconazole, posaconazole and anidulofungin) C.albicans isolate (fluconazole, itraconazole, posaconazole and anidulofungin). As a result in this study, it was determined thatboth methods were similar and can be used according to preference of laboratories. The CLSI antifungal susceptibility test results can be assessed at the end of 24 hour incubation, but sometimes it is important that the evaluation should be performed as a result of 48 hour incubation in slow growing species such as C.glabrata." @default.
• W2801375319 created "2018-05-17" @default.
• W2801375319 creator A5004722901 @default.
• W2801375319 creator A5006714037 @default.
• W2801375319 creator A5009976892 @default.
• W2801375319 creator A5015299453 @default.
• W2801375319 creator A5033000601 @default.
• W2801375319 creator A5043172347 @default.
• W2801375319 date "2018-01-15" @default.
• W2801375319 modified "2023-09-30" @default.
• W2801375319 title "Candida İzolatlarının Antifungal Duyarlılığının Belirlenmesinde Klinik Laboratuvar Standartları Enstitüsü (CLSI) ve Avrupa Antimikrobiyal Duyarlılık Testleri Komitesi (EUCAST) Sıvı Mikrodilüsyon Yöntemlerinin Karşılaştırılması" @default.
• W2801375319 doi "https://doi.org/10.5578/mb.63991" @default.
• W2801375319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29642828" @default.
• W2801375319 hasPublicationYear "2018" @default.
• W2801375319 type Work @default.
• W2801375319 sameAs 2801375319 @default.
• W2801375319 citedByCount "15" @default.
• W2801375319 countsByYear W28013753192018 @default.
• W2801375319 countsByYear W28013753192019 @default.
• W2801375319 countsByYear W28013753192020 @default.
• W2801375319 countsByYear W28013753192021 @default.
• W2801375319 countsByYear W28013753192022 @default.
• W2801375319 countsByYear W28013753192023 @default.
• W2801375319 crossrefType "journal-article" @default.
• W2801375319 hasAuthorship W2801375319A5004722901 @default.
• W2801375319 hasAuthorship W2801375319A5006714037 @default.
• W2801375319 hasAuthorship W2801375319A5009976892 @default.
• W2801375319 hasAuthorship W2801375319A5015299453 @default.
• W2801375319 hasAuthorship W2801375319A5033000601 @default.
• W2801375319 hasAuthorship W2801375319A5043172347 @default.
• W2801375319 hasConcept C176947019 @default.
• W2801375319 hasConcept C2775835631 @default.
• W2801375319 hasConcept C2776222947 @default.
• W2801375319 hasConcept C2777071850 @default.
• W2801375319 hasConcept C2778566413 @default.
• W2801375319 hasConcept C2779020398 @default.
• W2801375319 hasConcept C2779443200 @default.
• W2801375319 hasConcept C2779548794 @default.
• W2801375319 hasConcept C2779629538 @default.
• W2801375319 hasConcept C2780651595 @default.
• W2801375319 hasConcept C2780670043 @default.
• W2801375319 hasConcept C2780690907 @default.
• W2801375319 hasConcept C2780917455 @default.
• W2801375319 hasConcept C2780950330 @default.
• W2801375319 hasConcept C4937899 @default.
• W2801375319 hasConcept C86803240 @default.
• W2801375319 hasConcept C89423630 @default.
• W2801375319 hasConceptScore W2801375319C176947019 @default.
• W2801375319 hasConceptScore W2801375319C2775835631 @default.
• W2801375319 hasConceptScore W2801375319C2776222947 @default.
• W2801375319 hasConceptScore W2801375319C2777071850 @default.
• W2801375319 hasConceptScore W2801375319C2778566413 @default.
• W2801375319 hasConceptScore W2801375319C2779020398 @default.
• W2801375319 hasConceptScore W2801375319C2779443200 @default.
• W2801375319 hasConceptScore W2801375319C2779548794 @default.
• W2801375319 hasConceptScore W2801375319C2779629538 @default.
• W2801375319 hasConceptScore W2801375319C2780651595 @default.
• W2801375319 hasConceptScore W2801375319C2780670043 @default.
• W2801375319 hasConceptScore W2801375319C2780690907 @default.
• W2801375319 hasConceptScore W2801375319C2780917455 @default.
• W2801375319 hasConceptScore W2801375319C2780950330 @default.
• W2801375319 hasConceptScore W2801375319C4937899 @default.
• W2801375319 hasConceptScore W2801375319C86803240 @default.
• W2801375319 hasConceptScore W2801375319C89423630 @default.
• W2801375319 hasIssue "1" @default.
• W2801375319 hasLocation W28013753191 @default.
• W2801375319 hasLocation W28013753192 @default.
• W2801375319 hasOpenAccess W2801375319 @default.
• W2801375319 hasPrimaryLocation W28013753191 @default.
• W2801375319 hasRelatedWork W2011752164 @default.
• W2801375319 hasRelatedWork W2094393319 @default.
• W2801375319 hasRelatedWork W2098490735 @default.
• W2801375319 hasRelatedWork W2415479355 @default.
• W2801375319 hasRelatedWork W2910356989 @default.
• W2801375319 hasRelatedWork W2936232046 @default.
• W2801375319 hasRelatedWork W2945953134 @default.
• W2801375319 hasRelatedWork W3019897901 @default.
• W2801375319 hasRelatedWork W4285602388 @default.
• W2801375319 hasRelatedWork W4296514849 @default.
• W2801375319 hasVolume "52" @default.
• W2801375319 isParatext "false" @default.
• W2801375319 isRetracted "false" @default.
• W2801375319 magId "2801375319" @default.
• W2801375319 workType "article" @default.