Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801405524> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2801405524 abstract "The present study aimed to clarifying the effective and protective role of green tea (GT) against hepatotoxicity and oxidative damage induced by ketoconazol (KT) in male mice. Animals were divided into 6 groups, served as control (C), vehicle treated, KT treated, KT+GT treated, recovery (R) and R+ GT treated. Detection of cytochrome P450 (CYP1A1) was carried out by western blot, in addition to histopathological and biochemical studies. KT administration significant stimulated CYP1A1 in liver compared to control. Sever degenerative and histopathological changes in different treatments was also observed. In addition KT administration induces a significant elevation of lipid peroxidation (LPO), carbonyl protein (CP), total peroxide (TP), Alanine aminotransferase (ALT), aspartate aminotransferase (AST) and Lactate dehydrogenase (LDH) activities in blood plasma. Moreover, significant inhibition of hepatic superoxide dismutase (SOD), catalase (CAT), and depletion of hepatic reduced glutathione (GSH) were observed in different treatments after KT administration. The results of the present study showed that GT normalized hepatic levels of CYP1A1, LPO, CP, TP, CAT, SOD and GSH. The use of green tea protects the liver and reduces the destruction and inflammatory effects resulting from exposing to KT." @default.
- W2801405524 created "2018-05-17" @default.
- W2801405524 creator A5009813523 @default.
- W2801405524 creator A5079228985 @default.
- W2801405524 date "2017-12-01" @default.
- W2801405524 modified "2023-09-27" @default.
- W2801405524 title "THE PROTECTIVE AND TREATMENT ROLES OF GREEN TEA AGAINST HEPATOTOXICITY INDUCED BY KETOCONAZOL IN MALE MICE" @default.
- W2801405524 doi "https://doi.org/10.12816/0043183" @default.
- W2801405524 hasPublicationYear "2017" @default.
- W2801405524 type Work @default.
- W2801405524 sameAs 2801405524 @default.
- W2801405524 citedByCount "1" @default.
- W2801405524 countsByYear W28014055242021 @default.
- W2801405524 crossrefType "journal-article" @default.
- W2801405524 hasAuthorship W2801405524A5009813523 @default.
- W2801405524 hasAuthorship W2801405524A5079228985 @default.
- W2801405524 hasConcept C126322002 @default.
- W2801405524 hasConcept C134018914 @default.
- W2801405524 hasConcept C181199279 @default.
- W2801405524 hasConcept C185592680 @default.
- W2801405524 hasConcept C2775838275 @default.
- W2801405524 hasConcept C2776151105 @default.
- W2801405524 hasConcept C2777318727 @default.
- W2801405524 hasConcept C2778979269 @default.
- W2801405524 hasConcept C2780829032 @default.
- W2801405524 hasConcept C2992872382 @default.
- W2801405524 hasConcept C2993790521 @default.
- W2801405524 hasConcept C538909803 @default.
- W2801405524 hasConcept C55493867 @default.
- W2801405524 hasConcept C71924100 @default.
- W2801405524 hasConcept C98274493 @default.
- W2801405524 hasConceptScore W2801405524C126322002 @default.
- W2801405524 hasConceptScore W2801405524C134018914 @default.
- W2801405524 hasConceptScore W2801405524C181199279 @default.
- W2801405524 hasConceptScore W2801405524C185592680 @default.
- W2801405524 hasConceptScore W2801405524C2775838275 @default.
- W2801405524 hasConceptScore W2801405524C2776151105 @default.
- W2801405524 hasConceptScore W2801405524C2777318727 @default.
- W2801405524 hasConceptScore W2801405524C2778979269 @default.
- W2801405524 hasConceptScore W2801405524C2780829032 @default.
- W2801405524 hasConceptScore W2801405524C2992872382 @default.
- W2801405524 hasConceptScore W2801405524C2993790521 @default.
- W2801405524 hasConceptScore W2801405524C538909803 @default.
- W2801405524 hasConceptScore W2801405524C55493867 @default.
- W2801405524 hasConceptScore W2801405524C71924100 @default.
- W2801405524 hasConceptScore W2801405524C98274493 @default.
- W2801405524 hasLocation W28014055241 @default.
- W2801405524 hasOpenAccess W2801405524 @default.
- W2801405524 hasPrimaryLocation W28014055241 @default.
- W2801405524 hasRelatedWork W1616515595 @default.
- W2801405524 hasRelatedWork W2078406367 @default.
- W2801405524 hasRelatedWork W2092255422 @default.
- W2801405524 hasRelatedWork W2107270672 @default.
- W2801405524 hasRelatedWork W2109977783 @default.
- W2801405524 hasRelatedWork W2123273533 @default.
- W2801405524 hasRelatedWork W2131754309 @default.
- W2801405524 hasRelatedWork W2183696945 @default.
- W2801405524 hasRelatedWork W2186637737 @default.
- W2801405524 hasRelatedWork W2234586893 @default.
- W2801405524 hasRelatedWork W2365113747 @default.
- W2801405524 hasRelatedWork W2585208807 @default.
- W2801405524 hasRelatedWork W2766384201 @default.
- W2801405524 hasRelatedWork W2774836976 @default.
- W2801405524 hasRelatedWork W2924637769 @default.
- W2801405524 hasRelatedWork W2978175152 @default.
- W2801405524 hasRelatedWork W3087667846 @default.
- W2801405524 hasRelatedWork W3093939473 @default.
- W2801405524 hasRelatedWork W3159996108 @default.
- W2801405524 hasRelatedWork W2101442906 @default.
- W2801405524 isParatext "false" @default.
- W2801405524 isRetracted "false" @default.
- W2801405524 magId "2801405524" @default.
- W2801405524 workType "article" @default.