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• W2801452571 abstract "Individuals with heart failure (HF) have a high frequency of sleep problems. Patients with HF present with structural brain changes different from normal aging including reductions in brain volume, increases in white matter hyperintensity (WMH) and reduced cerebral blood flow. These structural changes in the brain may explain the pathophysiology of sleep and daytime problems. The objective of this study was to determine whether multimodal imaging data are related to self-reported sleep problems and daytime sleepiness in older adults with HF.Participants in this study underwent magnetic resonance imaging scans on the General Electric 3.0 T Discovery MR750 to acquire WMH, cerebral blood flow and brain volume. Data on 37 stable HF patients (mean age = 68; SD = 5.75) were included.In this sample, WMH was associated with daytime sleepiness (p = 0.025). However, gray and white matter volume and cerebral blood flow were not associated with daytime sleepiness, sleep quality or insomnia.Although further studies are needed to determine the relationship between WMH and sleep and daytime problems, the findings preliminarily support that increases in WMH from ischemic changes could explain increases in daytime sleepiness among people with HF." @default.
• W2801452571 created "2018-05-17" @default.
• W2801452571 creator A5006408859 @default.
• W2801452571 creator A5043910775 @default.
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• W2801452571 date "2018-05-28" @default.
• W2801452571 modified "2023-09-27" @default.
• W2801452571 title "Multimodal brain imaging investigation of self-reported sleep quality and daytime sleepiness in older adults with heart failure" @default.
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• W2801452571 doi "https://doi.org/10.1080/00207454.2018.1475374" @default.
• W2801452571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29745279" @default.
• W2801452571 hasPublicationYear "2018" @default.
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