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- W2801473557 abstract "Abstract Background Preanalytical, analytical, and postanalytical issues are often magnified in pediatric laboratories, and traditional vacuum-based blood tubes can contribute to some of these issues. Because of this, we investigated adopting an enclosed blood collection system that can perform vacuum or gentle aspiration blood collection, eliminating syringes, transfer device, and transfer steps, as well as potentially minimizing preanalytical error in the pediatric laboratory. We embarked on a validation of this tube system, in comparison with our current collection tubes, across most in-house tests at a large pediatric hospital. Methods Twenty adult volunteers were recruited. Blood was drawn into lithium heparin, serum, EDTA, and citrate tubes of each commercial tube type for comparison. For some tests, remnant blood from pediatric syringe draws was used when available. Samples were then processed and analyzed across all general areas of the clinical laboratory, and correlations of the results from the 2 tube systems were performed. Results Across 95 tests in the core laboratory and blood bank, almost all demonstrated clinically acceptable comparisons, with most R values >0.90. Only 3 of 95 tests demonstrated clinically significant differences between the tube systems. Conclusions Our validation of the enclosed blood collection system demonstrated acceptable results when compared with our current collection tubes. Additionally, with some minor modifications, our automated instruments could utilize ultralow-volume tubes from the enclosed blood collection system for direct tube sampling, which is impossible using our current small-volume tubes with our main chemistry analyzer." @default.
- W2801473557 created "2018-05-17" @default.
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- W2801473557 date "2018-07-01" @default.
- W2801473557 modified "2023-10-06" @default.
- W2801473557 title "Validation of an Enclosed Blood Collection System in a Pediatric Laboratory" @default.
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- W2801473557 doi "https://doi.org/10.1373/jalm.2017.025163" @default.
- W2801473557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33626827" @default.
- W2801473557 hasPublicationYear "2018" @default.
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