Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801486903> ?p ?o ?g. }
- W2801486903 endingPage "1843" @default.
- W2801486903 startingPage "1837" @default.
- W2801486903 abstract "Recently, p16 has been included in the TNM guideline for oropharyngeal carcinomas. The role of HPV and p16 in hypopharyngeal and laryngeal carcinomas has not yet been established sufficiently. Hundred and thirty-four patients with hypopharyngeal and laryngeal carcinomas were included in this retrospective analysis. Only patients with known HPV status were eligible for the investigation. Survival probabilities were estimated for different risk factors. Eighty-five patients presented with laryngeal carcinoma and 49 patients with hypopharyngeal carcinoma. 8% were HPV positive (10.6% laryngeal, 4.1% hypopharyngeal carcinoma). Median follow-up time was 58 months. We observed a significantly better overall survival for patients with an early tumor stage compared to advanced carcinoma. One of the hypopharyngeal HPV positive carcinomas was also p16 positive and one was p16 negative. Of the nine HPV positive laryngeal carcinomas, four were p16 positive and five p16 negative. Neither patients who were HPV positive nor patients positive for p16 showed a significantly better outcome than HPV or p16 negative patients. In contrast, nicotine pack-years showed a highly significant correlation with survival in our patient collective. The data suggest that tumor stage and nicotine exposure seem to have the highest impact on survival in hypopharyngeal and laryngeal squamous cell carcinoma patients. There is no evidence for a better survival for p16 positive or HPV positive patients with hypopharyngeal or laryngeal squamous cell carcinoma. HPV seems to play a minor role in these entities of head and neck carcinoma." @default.
- W2801486903 created "2018-05-17" @default.
- W2801486903 creator A5041719833 @default.
- W2801486903 creator A5067763748 @default.
- W2801486903 creator A5076214745 @default.
- W2801486903 creator A5080975285 @default.
- W2801486903 creator A5081043627 @default.
- W2801486903 creator A5084907442 @default.
- W2801486903 date "2018-05-09" @default.
- W2801486903 modified "2023-10-09" @default.
- W2801486903 title "Cancer stage and pack-years, but not p16 or HPV, are relevant for survival in hypopharyngeal and laryngeal squamous cell carcinomas" @default.
- W2801486903 cites W1969224935 @default.
- W2801486903 cites W1971211622 @default.
- W2801486903 cites W1996456132 @default.
- W2801486903 cites W2013793743 @default.
- W2801486903 cites W2015094703 @default.
- W2801486903 cites W2039997195 @default.
- W2801486903 cites W2102472011 @default.
- W2801486903 cites W2112600232 @default.
- W2801486903 cites W2114111016 @default.
- W2801486903 cites W2117647844 @default.
- W2801486903 cites W2118441422 @default.
- W2801486903 cites W2119516157 @default.
- W2801486903 cites W2123526038 @default.
- W2801486903 cites W2127605299 @default.
- W2801486903 cites W2145785884 @default.
- W2801486903 cites W2155029995 @default.
- W2801486903 cites W2320299038 @default.
- W2801486903 cites W2410036530 @default.
- W2801486903 cites W2524276769 @default.
- W2801486903 cites W2531155581 @default.
- W2801486903 cites W2573152477 @default.
- W2801486903 cites W2577561171 @default.
- W2801486903 doi "https://doi.org/10.1007/s00405-018-4997-1" @default.
- W2801486903 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5992237" @default.
- W2801486903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29744637" @default.
- W2801486903 hasPublicationYear "2018" @default.
- W2801486903 type Work @default.
- W2801486903 sameAs 2801486903 @default.
- W2801486903 citedByCount "19" @default.
- W2801486903 countsByYear W28014869032018 @default.
- W2801486903 countsByYear W28014869032019 @default.
- W2801486903 countsByYear W28014869032020 @default.
- W2801486903 countsByYear W28014869032021 @default.
- W2801486903 countsByYear W28014869032022 @default.
- W2801486903 countsByYear W28014869032023 @default.
- W2801486903 crossrefType "journal-article" @default.
- W2801486903 hasAuthorship W2801486903A5041719833 @default.
- W2801486903 hasAuthorship W2801486903A5067763748 @default.
- W2801486903 hasAuthorship W2801486903A5076214745 @default.
- W2801486903 hasAuthorship W2801486903A5080975285 @default.
- W2801486903 hasAuthorship W2801486903A5081043627 @default.
- W2801486903 hasAuthorship W2801486903A5084907442 @default.
- W2801486903 hasBestOaLocation W28014869031 @default.
- W2801486903 hasConcept C121608353 @default.
- W2801486903 hasConcept C126322002 @default.
- W2801486903 hasConcept C141071460 @default.
- W2801486903 hasConcept C143998085 @default.
- W2801486903 hasConcept C146357865 @default.
- W2801486903 hasConcept C151730666 @default.
- W2801486903 hasConcept C2776283816 @default.
- W2801486903 hasConcept C2777546739 @default.
- W2801486903 hasConcept C2779196318 @default.
- W2801486903 hasConcept C2780474809 @default.
- W2801486903 hasConcept C71924100 @default.
- W2801486903 hasConcept C86803240 @default.
- W2801486903 hasConceptScore W2801486903C121608353 @default.
- W2801486903 hasConceptScore W2801486903C126322002 @default.
- W2801486903 hasConceptScore W2801486903C141071460 @default.
- W2801486903 hasConceptScore W2801486903C143998085 @default.
- W2801486903 hasConceptScore W2801486903C146357865 @default.
- W2801486903 hasConceptScore W2801486903C151730666 @default.
- W2801486903 hasConceptScore W2801486903C2776283816 @default.
- W2801486903 hasConceptScore W2801486903C2777546739 @default.
- W2801486903 hasConceptScore W2801486903C2779196318 @default.
- W2801486903 hasConceptScore W2801486903C2780474809 @default.
- W2801486903 hasConceptScore W2801486903C71924100 @default.
- W2801486903 hasConceptScore W2801486903C86803240 @default.
- W2801486903 hasIssue "7" @default.
- W2801486903 hasLocation W28014869031 @default.
- W2801486903 hasLocation W28014869032 @default.
- W2801486903 hasLocation W28014869033 @default.
- W2801486903 hasLocation W28014869034 @default.
- W2801486903 hasOpenAccess W2801486903 @default.
- W2801486903 hasPrimaryLocation W28014869031 @default.
- W2801486903 hasRelatedWork W2126793477 @default.
- W2801486903 hasRelatedWork W2152218872 @default.
- W2801486903 hasRelatedWork W2163277987 @default.
- W2801486903 hasRelatedWork W2364092196 @default.
- W2801486903 hasRelatedWork W2373471017 @default.
- W2801486903 hasRelatedWork W2397802363 @default.
- W2801486903 hasRelatedWork W2556560126 @default.
- W2801486903 hasRelatedWork W3032219018 @default.
- W2801486903 hasRelatedWork W4294566497 @default.
- W2801486903 hasRelatedWork W2181144194 @default.
- W2801486903 hasVolume "275" @default.
- W2801486903 isParatext "false" @default.
- W2801486903 isRetracted "false" @default.