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- W2801500091 endingPage "2057" @default.
- W2801500091 startingPage "2024" @default.
- W2801500091 abstract "With an increase in the ageing population worldwide, the prevalence of osteoporosis increases at an alarming rate in both male and female irrespective of their ethnicity. At present, the currently available therapeutic options are mostly limited to either bone resorptive or bone forming efficacies and both approaches are associated with serious side effects. Despite these options, there is still need for newer therapeutics to treat osteoporosis, which can offer beneficial effects for maintaining balanced dynamics between bone formation and bone resorption, devoid of any side effect. The proper understanding of pathophysiology of the disease is essential for designing or investigating an effective and safe anti-osteoporotic agent. This review represents a discussion around the molecular targets with their implications in disease progression, available therapeutic options, the emerging targets, and the importance of designing an effective anti-osteoporotic agent." @default.
- W2801500091 created "2018-05-17" @default.
- W2801500091 creator A5012028636 @default.
- W2801500091 creator A5014236716 @default.
- W2801500091 creator A5032386875 @default.
- W2801500091 creator A5060048523 @default.
- W2801500091 date "2018-05-07" @default.
- W2801500091 modified "2023-10-03" @default.
- W2801500091 title "The underlying pathophysiology and therapeutic approaches for osteoporosis" @default.
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