FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801545378> ?p ?o ?g. }

• W2801545378 endingPage "271" @default.
• W2801545378 startingPage "271" @default.
• W2801545378 abstract "Is a single dose of gonadotropin-releasing hormone agonist (GnRHa) trigger to induce final oocyte maturation in polycystic ovarian syndrome (PCOS) undergoing in vitro fertilization (IVF) cycles with GnRH antagonist protocol sufficient to provide optimal oocyte maturity?This is a prospective, randomized, double-blind, proof-of-concept study.This study was carried out at a tertiary care center.A total of 125 patients diagnosed with PCOS defined as per the ESHRE/ASRM Rotterdam criteria (2003) undergoing IVF in antagonist protocol were randomized into two groups. Group A: single dose of GnRHa 0.2 mg, 35 h prior to oocyte retrieval, and Group B: 0.2 mg GnRHa 35 h prior to oocyte retrieval + repeat dose of 0.1 mg 12 h following the 1st dose. 12 h post-trigger, luteinizing hormone (LH), progesterone (P4), and follicle-stimulating hormone (FSH) values were estimated.Continuous variables were expressed as mean ± standard deviation and categorical variables as proportions where applicable. Independent sample t-test was used for continuous variables which were normally distributed and Mann-Whitney U-test for data not normally distributed. Chi-square test or Fisher's exact test was used for categorical variables where appropriate. Odds ratio (OR) with 95% confidence intervals (CIs) was calculated. In addition, receiver operating characteristic curve was used to evaluate the post-trigger LH, P4, and FSH values at 12 h as predictors of oocyte maturity.Primary outcome: maturity rate of the oocytes. Secondary outcomes: oocyte yield, fertilization rate, availability of good quality embryos on day 3, blastocyst conversion, OHSS rates, post-trigger serum LH (IU/L), FSH (IU/L), and P4 (ng/mL) levels implantation rate and clinical pregnancy rate.A higher number of mature (metaphase II) oocytes were obtained in Group B compared to Group A (OR of 0.47; CI: 0.38-0.57; P < 0.01). Significantly a higher number of blastocysts were obtained in Group B than Group A (4.00 vs. 3.04; P = 0.023). The odds of clinical pregnancy per patient were higher in Group B (OR = 0.56; CI [0.27-1.24]), with a trend towards better clinical pregnancy in Group B than in Group A.A repeat dose of GnRHa trigger 12 h following the first dose probably by maintaining a sustained level of gonadotropins yielded a better maturity of oocytes, higher number of blastocysts, and a trend towards higher clinical pregnancy than a single dose in PCOS patients undergoing IVF in antagonist cycles." @default.
• W2801545378 created "2018-05-17" @default.
• W2801545378 creator A5008017094 @default.
• W2801545378 creator A5032383485 @default.
• W2801545378 creator A5052186238 @default.
• W2801545378 creator A5059434525 @default.
• W2801545378 creator A5069122479 @default.
• W2801545378 creator A5086841790 @default.
• W2801545378 date "2017-01-01" @default.
• W2801545378 modified "2023-09-27" @default.
• W2801545378 title "Repeat dose of gonadotropin-releasing hormone agonist trigger in polycystic ovarian syndrome undergoing In Vitro fertilization cycles provides a better cycle outcome - a proof-of-concept study" @default.
• W2801545378 cites W1552354325 @default.
• W2801545378 cites W158447566 @default.
• W2801545378 cites W1598110035 @default.
• W2801545378 cites W1915329402 @default.
• W2801545378 cites W1930577626 @default.
• W2801545378 cites W1965768870 @default.
• W2801545378 cites W1970139299 @default.
• W2801545378 cites W1995145782 @default.
• W2801545378 cites W1996215930 @default.
• W2801545378 cites W2024374508 @default.
• W2801545378 cites W2029525282 @default.
• W2801545378 cites W2035848802 @default.
• W2801545378 cites W2041838883 @default.
• W2801545378 cites W2045434925 @default.
• W2801545378 cites W2059376854 @default.
• W2801545378 cites W2059733957 @default.
• W2801545378 cites W2060170224 @default.
• W2801545378 cites W2066964651 @default.
• W2801545378 cites W2070512684 @default.
• W2801545378 cites W2072699290 @default.
• W2801545378 cites W2087772008 @default.
• W2801545378 cites W2090894343 @default.
• W2801545378 cites W2091849572 @default.
• W2801545378 cites W2092573635 @default.
• W2801545378 cites W2099797616 @default.
• W2801545378 cites W2108512070 @default.
• W2801545378 cites W2114793225 @default.
• W2801545378 cites W2116307051 @default.
• W2801545378 cites W2117814169 @default.
• W2801545378 cites W2126897503 @default.
• W2801545378 cites W2136268403 @default.
• W2801545378 cites W2143104514 @default.
• W2801545378 cites W2143564115 @default.
• W2801545378 cites W2146771682 @default.
• W2801545378 cites W2148002734 @default.
• W2801545378 cites W2150267695 @default.
• W2801545378 cites W2155645913 @default.
• W2801545378 cites W2159529998 @default.
• W2801545378 cites W2166155097 @default.
• W2801545378 cites W2186218348 @default.
• W2801545378 cites W2411007844 @default.
• W2801545378 doi "https://doi.org/10.4103/jhrs.jhrs_102_17" @default.
• W2801545378 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5799931" @default.
• W2801545378 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29430154" @default.
• W2801545378 hasPublicationYear "2017" @default.
• W2801545378 type Work @default.
• W2801545378 sameAs 2801545378 @default.
• W2801545378 citedByCount "6" @default.
• W2801545378 countsByYear W28015453782019 @default.
• W2801545378 countsByYear W28015453782020 @default.
• W2801545378 countsByYear W28015453782021 @default.
• W2801545378 countsByYear W28015453782022 @default.
• W2801545378 crossrefType "journal-article" @default.
• W2801545378 hasAuthorship W2801545378A5008017094 @default.
• W2801545378 hasAuthorship W2801545378A5032383485 @default.
• W2801545378 hasAuthorship W2801545378A5052186238 @default.
• W2801545378 hasAuthorship W2801545378A5059434525 @default.
• W2801545378 hasAuthorship W2801545378A5069122479 @default.
• W2801545378 hasAuthorship W2801545378A5086841790 @default.
• W2801545378 hasBestOaLocation W28015453781 @default.
• W2801545378 hasConcept C126322002 @default.
• W2801545378 hasConcept C142773365 @default.
• W2801545378 hasConcept C16685009 @default.
• W2801545378 hasConcept C196843134 @default.
• W2801545378 hasConcept C2776600139 @default.
• W2801545378 hasConcept C2776690073 @default.
• W2801545378 hasConcept C2777391703 @default.
• W2801545378 hasConcept C2777688143 @default.
• W2801545378 hasConcept C2777886879 @default.
• W2801545378 hasConcept C2778575703 @default.
• W2801545378 hasConcept C2778782382 @default.
• W2801545378 hasConcept C2778894405 @default.
• W2801545378 hasConcept C2779192864 @default.
• W2801545378 hasConcept C2779234561 @default.
• W2801545378 hasConcept C2779306644 @default.
• W2801545378 hasConcept C2781065240 @default.
• W2801545378 hasConcept C29456083 @default.
• W2801545378 hasConcept C3018442814 @default.
• W2801545378 hasConcept C46699223 @default.
• W2801545378 hasConcept C512716672 @default.
• W2801545378 hasConcept C54355233 @default.
• W2801545378 hasConcept C71315377 @default.
• W2801545378 hasConcept C71924100 @default.
• W2801545378 hasConcept C86803240 @default.
• W2801545378 hasConcept C95444343 @default.
• W2801545378 hasConceptScore W2801545378C126322002 @default.
• W2801545378 hasConceptScore W2801545378C142773365 @default.

• next