Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801652604> ?p ?o ?g. }
Showing items 1 to 56 of
56
with 100 items per page.
- W2801652604 abstract "Elaeagnus angustifolia L. has a long history of use in ethnopharmacology. Only few studies examined the potential activities of the leaves. Furthermore, the leaves’ chemical composition was not fully investigated. In this study, the chemical composition of E. angustifolia leaves extract was analysed and major compounds were isolated and identified. Extract obtained by maceration was further extracted with solvents differing in their polarity then submitted to open column chromatography, followed by isolation of major compounds. They were analysed using UV-Vis and/or NMR. One terpene (β-sitosterol) and four flavonoids (chrysin-7-glucoside, rutin, luteolin and kaempferol) were isolated and identified. For the biological activities, leaves were extracted using ethanol, ethyl acetate, chloroform and water. Anti-angiogenic activity was studied by rat aortic ring assay. Anti-proliferative activity was studied against MCF-7 and T-47D breast cancer cell lines. Ethyl acetate extract was found cytotoxic against T-47D breast cancer cell line (IC50=23.05 μg/mL). Potent anti-angiogenic activity of ethanol-(IC50=3.039 μg/mL), ethyl acetate- (IC50=6.289 μg/mL) and water-extract (IC50=7.153 μg/mL) was reported for the first time." @default.
- W2801652604 created "2018-05-17" @default.
- W2801652604 creator A5010659599 @default.
- W2801652604 creator A5021007368 @default.
- W2801652604 creator A5023076917 @default.
- W2801652604 creator A5039598696 @default.
- W2801652604 creator A5056324208 @default.
- W2801652604 creator A5083818325 @default.
- W2801652604 creator A5089354583 @default.
- W2801652604 date "2018-01-01" @default.
- W2801652604 modified "2023-09-26" @default.
- W2801652604 title "Phytochemical Analysis and Evaluation of Anti-angiogenic and Antiproliferative Activities of the Leaves of Elaeagnus angustifolia L. Grown in Jordan" @default.
- W2801652604 doi "https://doi.org/10.4172/2329-6836.1000319" @default.
- W2801652604 hasPublicationYear "2018" @default.
- W2801652604 type Work @default.
- W2801652604 sameAs 2801652604 @default.
- W2801652604 citedByCount "1" @default.
- W2801652604 countsByYear W28016526042023 @default.
- W2801652604 crossrefType "journal-article" @default.
- W2801652604 hasAuthorship W2801652604A5010659599 @default.
- W2801652604 hasAuthorship W2801652604A5021007368 @default.
- W2801652604 hasAuthorship W2801652604A5023076917 @default.
- W2801652604 hasAuthorship W2801652604A5039598696 @default.
- W2801652604 hasAuthorship W2801652604A5056324208 @default.
- W2801652604 hasAuthorship W2801652604A5083818325 @default.
- W2801652604 hasAuthorship W2801652604A5089354583 @default.
- W2801652604 hasBestOaLocation W28016526041 @default.
- W2801652604 hasConcept C195475562 @default.
- W2801652604 hasConcept C556039675 @default.
- W2801652604 hasConcept C59822182 @default.
- W2801652604 hasConcept C71924100 @default.
- W2801652604 hasConcept C86803240 @default.
- W2801652604 hasConceptScore W2801652604C195475562 @default.
- W2801652604 hasConceptScore W2801652604C556039675 @default.
- W2801652604 hasConceptScore W2801652604C59822182 @default.
- W2801652604 hasConceptScore W2801652604C71924100 @default.
- W2801652604 hasConceptScore W2801652604C86803240 @default.
- W2801652604 hasIssue "03" @default.
- W2801652604 hasLocation W28016526041 @default.
- W2801652604 hasOpenAccess W2801652604 @default.
- W2801652604 hasPrimaryLocation W28016526041 @default.
- W2801652604 hasRelatedWork W1987992465 @default.
- W2801652604 hasRelatedWork W1989089042 @default.
- W2801652604 hasRelatedWork W2032251647 @default.
- W2801652604 hasRelatedWork W2062604169 @default.
- W2801652604 hasRelatedWork W2608729255 @default.
- W2801652604 hasRelatedWork W4200356890 @default.
- W2801652604 hasRelatedWork W4287683465 @default.
- W2801652604 hasRelatedWork W175741450 @default.
- W2801652604 hasRelatedWork W2182853506 @default.
- W2801652604 hasRelatedWork W3120493284 @default.
- W2801652604 hasVolume "06" @default.
- W2801652604 isParatext "false" @default.
- W2801652604 isRetracted "false" @default.
- W2801652604 magId "2801652604" @default.
- W2801652604 workType "article" @default.