Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801670515> ?p ?o ?g. }
- W2801670515 endingPage "628" @default.
- W2801670515 startingPage "611" @default.
- W2801670515 abstract "Ovine trophectoderm (oTr1) cells were used to investigate effects of epinephrine (EP), norepinephrine (NE), and dopamine (DA) on their proliferation, migration and adhesion, secretion of interferon tau (IFNT), and expression of genes for synthesis of polyamines and apoptosis. Expression of mRNAs for agmatinase (AGMAT), arginine decarboxylase (ADC), ornithine decarboxylase (ODC1), and solute carrier family 7 (SLC7A1) (cationic amino acid transporter, Y + system), member 1 increased (P < 0.05) in oTr1 cells in response to EP and DA. However, expression of SLC7A1 decreased at high doses of EP and expression of ADC mRNA by oTr1 cells decreased in response to 20 and 40 ng/ml NE, and 40 ng/ml DA. Migration of oTr1 cells increased in response to EP, DA, and NE after 48 h of treatment. However, proliferation of oTr1 cells was inhibited by 300 pg/ml EP after 96 h and DA at 20 and 100 ng/ml. EP increased adhesion of oTr1 cells. The secretion of IFNT increased in response to 300 pg/ml EP, 100 ng/ml NE and DA after 48 h and at 96 h, and both DA (40 ng/ml) and NE (100 ng/ml). Expression of mRNAs for apoptotic genes (caspase 3, cathpsin B, BCL2 associated X protein “bax,” B-cell lymphoma 2 “bcl2,” and proto-oncogene “cmyc”) decreased (P < 0.05) in response to catecholamines, but DA did not affect (P < 0.05) expression of cMYC mRNA. These results indicate that catecholamines play important roles in conceptus development during the peri-implantation period of pregnancy through effects on synthesis of polyamines, secretion of IFNT, and expression of apoptotic genes by oTr1 cells." @default.
- W2801670515 created "2018-05-17" @default.
- W2801670515 creator A5024788286 @default.
- W2801670515 creator A5044475205 @default.
- W2801670515 creator A5072274558 @default.
- W2801670515 creator A5089273124 @default.
- W2801670515 date "2018-04-12" @default.
- W2801670515 modified "2023-09-26" @default.
- W2801670515 title "Effects of catecholamines on secretion of interferon tau and expression of genes for synthesis of polyamines and apoptosis by ovine trophectoderm†" @default.
- W2801670515 cites W1193862271 @default.
- W2801670515 cites W1484675846 @default.
- W2801670515 cites W1549834656 @default.
- W2801670515 cites W1574832949 @default.
- W2801670515 cites W1861053103 @default.
- W2801670515 cites W1934389460 @default.
- W2801670515 cites W1972584259 @default.
- W2801670515 cites W1974620743 @default.
- W2801670515 cites W1978189045 @default.
- W2801670515 cites W1979673253 @default.
- W2801670515 cites W1983176420 @default.
- W2801670515 cites W1992269617 @default.
- W2801670515 cites W1999299319 @default.
- W2801670515 cites W2001562379 @default.
- W2801670515 cites W2013628786 @default.
- W2801670515 cites W2016465427 @default.
- W2801670515 cites W2019631673 @default.
- W2801670515 cites W2021686444 @default.
- W2801670515 cites W2023550300 @default.
- W2801670515 cites W2025233095 @default.
- W2801670515 cites W2032079892 @default.
- W2801670515 cites W2032806930 @default.
- W2801670515 cites W2034139245 @default.
- W2801670515 cites W2035045680 @default.
- W2801670515 cites W2047449662 @default.
- W2801670515 cites W2047581757 @default.
- W2801670515 cites W2051294130 @default.
- W2801670515 cites W2053348857 @default.
- W2801670515 cites W2054860206 @default.
- W2801670515 cites W2056195936 @default.
- W2801670515 cites W2061215768 @default.
- W2801670515 cites W2066277278 @default.
- W2801670515 cites W2073918561 @default.
- W2801670515 cites W2074321417 @default.
- W2801670515 cites W2082183947 @default.
- W2801670515 cites W2089101049 @default.
- W2801670515 cites W2096430572 @default.
- W2801670515 cites W2097317908 @default.
- W2801670515 cites W2098070096 @default.
- W2801670515 cites W2102607537 @default.
- W2801670515 cites W2104183234 @default.
- W2801670515 cites W2109142667 @default.
- W2801670515 cites W2113700357 @default.
- W2801670515 cites W2115651516 @default.
- W2801670515 cites W2116070039 @default.
- W2801670515 cites W2116562692 @default.
- W2801670515 cites W2116574982 @default.
- W2801670515 cites W2123404727 @default.
- W2801670515 cites W2124673755 @default.
- W2801670515 cites W2127134752 @default.
- W2801670515 cites W2127318107 @default.
- W2801670515 cites W2127469663 @default.
- W2801670515 cites W2128890381 @default.
- W2801670515 cites W2130852301 @default.
- W2801670515 cites W2134322174 @default.
- W2801670515 cites W2138366746 @default.
- W2801670515 cites W2138792241 @default.
- W2801670515 cites W2148251928 @default.
- W2801670515 cites W2149080950 @default.
- W2801670515 cites W2149487627 @default.
- W2801670515 cites W2150029996 @default.
- W2801670515 cites W2154162328 @default.
- W2801670515 cites W2156483686 @default.
- W2801670515 cites W2164116735 @default.
- W2801670515 cites W2167053288 @default.
- W2801670515 cites W2168172261 @default.
- W2801670515 cites W2168874351 @default.
- W2801670515 cites W2181852091 @default.
- W2801670515 cites W2240976091 @default.
- W2801670515 cites W2340591569 @default.
- W2801670515 cites W2461686980 @default.
- W2801670515 cites W2605009367 @default.
- W2801670515 cites W2623634164 @default.
- W2801670515 cites W2739443933 @default.
- W2801670515 cites W2749339780 @default.
- W2801670515 cites W3009718084 @default.
- W2801670515 doi "https://doi.org/10.1093/biolre/ioy085" @default.
- W2801670515 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29668843" @default.
- W2801670515 hasPublicationYear "2018" @default.
- W2801670515 type Work @default.
- W2801670515 sameAs 2801670515 @default.
- W2801670515 citedByCount "16" @default.
- W2801670515 countsByYear W28016705152018 @default.
- W2801670515 countsByYear W28016705152019 @default.
- W2801670515 countsByYear W28016705152020 @default.
- W2801670515 countsByYear W28016705152021 @default.
- W2801670515 countsByYear W28016705152022 @default.
- W2801670515 countsByYear W28016705152023 @default.
- W2801670515 crossrefType "journal-article" @default.