FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801689984> ?p ?o ?g. }

• W2801689984 endingPage "1279" @default.
• W2801689984 startingPage "1273" @default.
• W2801689984 abstract "<h3>BACKGROUND AND PURPOSE:</h3> Chronic hemodynamic impairment in high-grade carotid occlusive disease is thought to cause microstructural abnormalities that might be subclinical or lead to subtle symptoms including cognitive impairment. Quantitative MR imaging allows assessing pathologic structural changes beyond macroscopically visible tissue damage. In this study, high-resolution quantitative T2 mapping combined with DSC-based PWI was used to investigate quantitative T2 changes as a potential marker of microstructural damage in relation to hemodynamic impairment in patients with unilateral high-grade carotid occlusive disease. <h3>MATERIALS AND METHODS:</h3> Eighteen patients with unilateral high-grade ICA or MCA stenosis/occlusion were included in the study. T2 values and deconvolved perfusion parameters, including relative CBF, relative CBV, and the relative CBF/relative CBV ratio as a potential indicator of local cerebral perfusion pressure, were determined within areas with delayed TTP and compared with values from contralateral unaffected areas after segmentation of normal-appearing hypoperfused WM and cortical regions. Hemispheric asymmetry indices were calculated for all parameters. <h3>RESULTS:</h3> Quantitative T2 was significantly prolonged (<i>P</i> < .01) in hypoperfused tissue and correlated significantly (<i>P</i> < .01) with TTP delay and relative CBF/relative CBV reduction in WM. Significant correlations (<i>P</i> < .001) between TTP delay and the relative CBF/relative CBV ratio were found both in WM and in cortical areas. <h3>CONCLUSIONS:</h3> Quantitative T2 can be used as a marker of microstructural tissue damage even in normal-appearing GM and WM within a vascular territory affected by high-grade carotid occlusive disease. Furthermore, the extent of damage correlates with the degree of hemodynamic failure measured by DSC perfusion parameters." @default.
• W2801689984 created "2018-05-17" @default.
• W2801689984 creator A5004747788 @default.
• W2801689984 creator A5049457587 @default.
• W2801689984 creator A5049476139 @default.
• W2801689984 creator A5055812661 @default.
• W2801689984 creator A5059467238 @default.
• W2801689984 creator A5060982379 @default.
• W2801689984 creator A5091140500 @default.
• W2801689984 date "2018-05-10" @default.
• W2801689984 modified "2023-09-27" @default.
• W2801689984 title "Extent of Microstructural Tissue Damage Correlates with Hemodynamic Failure in High-Grade Carotid Occlusive Disease: An MRI Study Using Quantitative T2 and DSC Perfusion" @default.
• W2801689984 cites W1001620100 @default.
• W2801689984 cites W1982699469 @default.
• W2801689984 cites W1985043486 @default.
• W2801689984 cites W1987369532 @default.
• W2801689984 cites W1991811241 @default.
• W2801689984 cites W1996586146 @default.
• W2801689984 cites W1997938840 @default.
• W2801689984 cites W2025171492 @default.
• W2801689984 cites W2032166809 @default.
• W2801689984 cites W2047232697 @default.
• W2801689984 cites W2056458803 @default.
• W2801689984 cites W2060157715 @default.
• W2801689984 cites W2062901604 @default.
• W2801689984 cites W2066453549 @default.
• W2801689984 cites W2079258796 @default.
• W2801689984 cites W2103134658 @default.
• W2801689984 cites W2110855618 @default.
• W2801689984 cites W2116785837 @default.
• W2801689984 cites W2136573752 @default.
• W2801689984 cites W2137324084 @default.
• W2801689984 cites W2148597666 @default.
• W2801689984 cites W2156398639 @default.
• W2801689984 cites W2158188707 @default.
• W2801689984 cites W2158807672 @default.
• W2801689984 cites W2190296239 @default.
• W2801689984 cites W2315272287 @default.
• W2801689984 cites W2326264490 @default.
• W2801689984 doi "https://doi.org/10.3174/ajnr.a5666" @default.
• W2801689984 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7655436" @default.
• W2801689984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29748200" @default.
• W2801689984 hasPublicationYear "2018" @default.
• W2801689984 type Work @default.
• W2801689984 sameAs 2801689984 @default.
• W2801689984 citedByCount "5" @default.
• W2801689984 countsByYear W28016899842019 @default.
• W2801689984 countsByYear W28016899842020 @default.
• W2801689984 countsByYear W28016899842021 @default.
• W2801689984 countsByYear W28016899842023 @default.
• W2801689984 crossrefType "journal-article" @default.
• W2801689984 hasAuthorship W2801689984A5004747788 @default.
• W2801689984 hasAuthorship W2801689984A5049457587 @default.
• W2801689984 hasAuthorship W2801689984A5049476139 @default.
• W2801689984 hasAuthorship W2801689984A5055812661 @default.
• W2801689984 hasAuthorship W2801689984A5059467238 @default.
• W2801689984 hasAuthorship W2801689984A5060982379 @default.
• W2801689984 hasAuthorship W2801689984A5091140500 @default.
• W2801689984 hasBestOaLocation W28016899841 @default.
• W2801689984 hasConcept C126322002 @default.
• W2801689984 hasConcept C126838900 @default.
• W2801689984 hasConcept C143409427 @default.
• W2801689984 hasConcept C146957229 @default.
• W2801689984 hasConcept C157767197 @default.
• W2801689984 hasConcept C164705383 @default.
• W2801689984 hasConcept C178853913 @default.
• W2801689984 hasConcept C2989005 @default.
• W2801689984 hasConcept C71924100 @default.
• W2801689984 hasConceptScore W2801689984C126322002 @default.
• W2801689984 hasConceptScore W2801689984C126838900 @default.
• W2801689984 hasConceptScore W2801689984C143409427 @default.
• W2801689984 hasConceptScore W2801689984C146957229 @default.
• W2801689984 hasConceptScore W2801689984C157767197 @default.
• W2801689984 hasConceptScore W2801689984C164705383 @default.
• W2801689984 hasConceptScore W2801689984C178853913 @default.
• W2801689984 hasConceptScore W2801689984C2989005 @default.
• W2801689984 hasConceptScore W2801689984C71924100 @default.
• W2801689984 hasIssue "7" @default.
• W2801689984 hasLocation W28016899841 @default.
• W2801689984 hasLocation W28016899842 @default.
• W2801689984 hasOpenAccess W2801689984 @default.
• W2801689984 hasPrimaryLocation W28016899841 @default.
• W2801689984 hasRelatedWork W1977221321 @default.
• W2801689984 hasRelatedWork W1983924596 @default.
• W2801689984 hasRelatedWork W2024932886 @default.
• W2801689984 hasRelatedWork W2162999504 @default.
• W2801689984 hasRelatedWork W2312614836 @default.
• W2801689984 hasRelatedWork W2358987067 @default.
• W2801689984 hasRelatedWork W2368632331 @default.
• W2801689984 hasRelatedWork W2418688449 @default.
• W2801689984 hasRelatedWork W2437180545 @default.
• W2801689984 hasRelatedWork W4383566828 @default.
• W2801689984 hasVolume "39" @default.
• W2801689984 isParatext "false" @default.
• W2801689984 isRetracted "false" @default.
• W2801689984 magId "2801689984" @default.
• W2801689984 workType "article" @default.