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• W2801714377 abstract "Skeletal muscle remodeling in response to terrestrial acclimation improves the locomotor performance of some amphibious fishes on land, but the cue for this remodeling is unknown. We tested the hypothesis that muscle remodeling in the amphibious Kryptolebias marmoratus on land is driven by higher O2 availability in atmospheric air, and the alternative hypothesis that remodeling is induced by a different environmental or physiological condition fish experience on land. Fish were acclimated to 28 days of air, aquatic hyperoxia, hypercapnia, hypoxia, elevated temperature, or fasting conditions. Air, fasting, and hyperoxic conditions increased (&gt;25%) the size of oxidative fibers in K. marmoratus while hypoxia had the reverse effect (23% decrease). Surprisingly, hyperoxia-acclimation also resulted in a transformation of the musculature to include large bands of oxidative-like muscle. Our results show that K. marmoratus is highly responsive to environmental O2 levels and capitalize on O2-rich opportunities to enhance O2 utilization by skeletal muscle." @default.
• W2801714377 created "2018-05-17" @default.
• W2801714377 creator A5004676469 @default.
• W2801714377 creator A5065836106 @default.
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• W2801714377 date "2018-01-01" @default.
• W2801714377 modified "2023-09-25" @default.
• W2801714377 title "Oxygen drives skeletal muscle remodeling in an amphibious fish out of water" @default.
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• W2801714377 doi "https://doi.org/10.1242/jeb.180257" @default.
• W2801714377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29691310" @default.
• W2801714377 hasPublicationYear "2018" @default.
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