Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801794321> ?p ?o ?g. }
- W2801794321 endingPage "1472" @default.
- W2801794321 startingPage "1464" @default.
- W2801794321 abstract "Chronic exposure to arsenic, an inducer of oxidative stress, is one of the major causes of male infertility. Therefore, the present study investigated the protective role of Ellagic acid (EA), as a natural antioxidant, against testicular toxicity evoked by arsenic. Thirty-five male Wistar rats were divided into 5 treatment groups. Group 1 served as control, group 2 were orally exposed to sodium arsenite (SA, 10 mg/kg; 21 days), groups 3 and 4 were initially exposed to SA for 7 days and then were treated with both EA (10 and 30 mg/kg) and SA up to 21 days, and group 5 was treated with EA for 14 days. After this period, biochemical and histopathological parameters were evaluated in serum samples and testicular tissue. SA markedly reduced levels of serum testosterone, total antioxidant capacity, reduced glutathione as well as the activity of antioxidant enzymes. Furthermore, SA enhanced levels of malondialdehyde, tumor necrosis factor-α, interleukin-1β and nitric oxide in testes. Treatment with EA was found to reduce testicular arsenic accumulation and oxidative stress parameters. In addition, EA improved the serum testosterone level, testicular antioxidant markers and histological parameters after exposure to SA. EA may emerge as a promising therapeutic option to protect testes from arsenic-induced toxicity through reducing oxidative stress and inflammatory responses." @default.
- W2801794321 created "2018-05-17" @default.
- W2801794321 creator A5008295064 @default.
- W2801794321 creator A5016939868 @default.
- W2801794321 creator A5045837328 @default.
- W2801794321 creator A5056404135 @default.
- W2801794321 creator A5073873190 @default.
- W2801794321 creator A5088175575 @default.
- W2801794321 date "2018-07-01" @default.
- W2801794321 modified "2023-10-06" @default.
- W2801794321 title "Ellagic acid: A promising protective remedy against testicular toxicity induced by arsenic" @default.
- W2801794321 cites W1444350444 @default.
- W2801794321 cites W1606756404 @default.
- W2801794321 cites W1666273112 @default.
- W2801794321 cites W1956023723 @default.
- W2801794321 cites W1968242477 @default.
- W2801794321 cites W1968475866 @default.
- W2801794321 cites W1984140215 @default.
- W2801794321 cites W1984810473 @default.
- W2801794321 cites W1988071963 @default.
- W2801794321 cites W1988217531 @default.
- W2801794321 cites W1988567818 @default.
- W2801794321 cites W1989180984 @default.
- W2801794321 cites W1995654099 @default.
- W2801794321 cites W1997430154 @default.
- W2801794321 cites W1998087553 @default.
- W2801794321 cites W2022783151 @default.
- W2801794321 cites W2026494761 @default.
- W2801794321 cites W2027307634 @default.
- W2801794321 cites W2028402334 @default.
- W2801794321 cites W2031153505 @default.
- W2801794321 cites W2033431595 @default.
- W2801794321 cites W2044659368 @default.
- W2801794321 cites W2054637747 @default.
- W2801794321 cites W2072898133 @default.
- W2801794321 cites W2077940658 @default.
- W2801794321 cites W2086382151 @default.
- W2801794321 cites W2086700107 @default.
- W2801794321 cites W2108092128 @default.
- W2801794321 cites W2109230097 @default.
- W2801794321 cites W2113970233 @default.
- W2801794321 cites W2118074210 @default.
- W2801794321 cites W2123132519 @default.
- W2801794321 cites W2128473487 @default.
- W2801794321 cites W2157095642 @default.
- W2801794321 cites W2158802701 @default.
- W2801794321 cites W2158942860 @default.
- W2801794321 cites W2162555240 @default.
- W2801794321 cites W2171599438 @default.
- W2801794321 cites W2281717745 @default.
- W2801794321 cites W2306172095 @default.
- W2801794321 cites W2318850941 @default.
- W2801794321 cites W2327218868 @default.
- W2801794321 cites W2343683417 @default.
- W2801794321 cites W2406434368 @default.
- W2801794321 cites W2414968819 @default.
- W2801794321 cites W2468464664 @default.
- W2801794321 cites W2492821432 @default.
- W2801794321 cites W2503130819 @default.
- W2801794321 cites W2533113519 @default.
- W2801794321 cites W2582261583 @default.
- W2801794321 cites W2586593047 @default.
- W2801794321 cites W2605974046 @default.
- W2801794321 cites W2623622179 @default.
- W2801794321 cites W2750163188 @default.
- W2801794321 cites W2751369155 @default.
- W2801794321 cites W2769245858 @default.
- W2801794321 cites W2778166987 @default.
- W2801794321 cites W2793068416 @default.
- W2801794321 cites W2793864420 @default.
- W2801794321 cites W4293247451 @default.
- W2801794321 doi "https://doi.org/10.1016/j.biopha.2018.04.194" @default.
- W2801794321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29864931" @default.
- W2801794321 hasPublicationYear "2018" @default.
- W2801794321 type Work @default.
- W2801794321 sameAs 2801794321 @default.
- W2801794321 citedByCount "40" @default.
- W2801794321 countsByYear W28017943212018 @default.
- W2801794321 countsByYear W28017943212019 @default.
- W2801794321 countsByYear W28017943212020 @default.
- W2801794321 countsByYear W28017943212021 @default.
- W2801794321 countsByYear W28017943212022 @default.
- W2801794321 countsByYear W28017943212023 @default.
- W2801794321 crossrefType "journal-article" @default.
- W2801794321 hasAuthorship W2801794321A5008295064 @default.
- W2801794321 hasAuthorship W2801794321A5016939868 @default.
- W2801794321 hasAuthorship W2801794321A5045837328 @default.
- W2801794321 hasAuthorship W2801794321A5056404135 @default.
- W2801794321 hasAuthorship W2801794321A5073873190 @default.
- W2801794321 hasAuthorship W2801794321A5088175575 @default.
- W2801794321 hasConcept C126322002 @default.
- W2801794321 hasConcept C134018914 @default.
- W2801794321 hasConcept C172507514 @default.
- W2801794321 hasConcept C178790620 @default.
- W2801794321 hasConcept C181199279 @default.
- W2801794321 hasConcept C185592680 @default.
- W2801794321 hasConcept C2776151105 @default.
- W2801794321 hasConcept C2778004101 @default.