FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2801919020> ?p ?o ?g. }

• W2801919020 endingPage "2917" @default.
• W2801919020 startingPage "2909" @default.
• W2801919020 abstract "Abstract Motivation ChIP-seq experiments that are aimed at detecting DNA-protein interactions require biological replication to draw inferential conclusions, however there is no current consensus on how to analyze ChIP-seq data with biological replicates. Very few methodologies exist for the joint analysis of replicated ChIP-seq data, with approaches ranging from combining the results of analyzing replicates individually to joint modeling of all replicates. Combining the results of individual replicates analyzed separately can lead to reduced peak classification performance compared to joint modeling. Currently available methods for joint analysis may fail to control the false discovery rate at the nominal level. Results We propose BinQuasi, a peak caller for replicated ChIP-seq data, that jointly models biological replicates using a generalized linear model framework and employs a one-sided quasi-likelihood ratio test to detect peaks. When applied to simulated data and real datasets, BinQuasi performs favorably compared to existing methods, including better control of false discovery rate than existing joint modeling approaches. BinQuasi offers a flexible approach to joint modeling of replicated ChIP-seq data which is preferable to combining the results of replicates analyzed individually. Availability and implementation Source code is freely available for download at https://cran.r-project.org/package=BinQuasi, implemented in R. Supplementary information Supplementary data are available at Bioinformatics online." @default.
• W2801919020 created "2018-05-17" @default.
• W2801919020 creator A5007803202 @default.
• W2801919020 creator A5018814025 @default.
• W2801919020 creator A5055838753 @default.
• W2801919020 creator A5072102359 @default.
• W2801919020 date "2018-04-19" @default.
• W2801919020 modified "2023-10-05" @default.
• W2801919020 title "BinQuasi: a peak detection method for ChIP-sequencing data with biological replicates" @default.
• W2801919020 cites W1490261451 @default.
• W2801919020 cites W1564246054 @default.
• W2801919020 cites W1596515083 @default.
• W2801919020 cites W1966921801 @default.
• W2801919020 cites W1967656072 @default.
• W2801919020 cites W1984001597 @default.
• W2801919020 cites W2013336813 @default.
• W2801919020 cites W2014677321 @default.
• W2801919020 cites W2018604728 @default.
• W2801919020 cites W2049684926 @default.
• W2801919020 cites W2052562387 @default.
• W2801919020 cites W2058358568 @default.
• W2801919020 cites W2067339099 @default.
• W2801919020 cites W2085184586 @default.
• W2801919020 cites W2090642023 @default.
• W2801919020 cites W2099107563 @default.
• W2801919020 cites W2099698839 @default.
• W2801919020 cites W2102904139 @default.
• W2801919020 cites W2103243650 @default.
• W2801919020 cites W2104323764 @default.
• W2801919020 cites W2104836314 @default.
• W2801919020 cites W2108234281 @default.
• W2801919020 cites W2108614159 @default.
• W2801919020 cites W2109897790 @default.
• W2801919020 cites W2109906618 @default.
• W2801919020 cites W2117255447 @default.
• W2801919020 cites W2124514674 @default.
• W2801919020 cites W2124717826 @default.
• W2801919020 cites W2124985265 @default.
• W2801919020 cites W2130116522 @default.
• W2801919020 cites W2131610374 @default.
• W2801919020 cites W2137857624 @default.
• W2801919020 cites W2144784334 @default.
• W2801919020 cites W2146303939 @default.
• W2801919020 cites W2146648681 @default.
• W2801919020 cites W2149627698 @default.
• W2801919020 cites W2156631105 @default.
• W2801919020 cites W2158226173 @default.
• W2801919020 cites W2163262940 @default.
• W2801919020 cites W2163845664 @default.
• W2801919020 cites W2170222864 @default.
• W2801919020 cites W2170830174 @default.
• W2801919020 cites W2171808845 @default.
• W2801919020 cites W2520401971 @default.
• W2801919020 cites W3104066961 @default.
• W2801919020 doi "https://doi.org/10.1093/bioinformatics/bty227" @default.
• W2801919020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29684098" @default.
• W2801919020 hasPublicationYear "2018" @default.
• W2801919020 type Work @default.
• W2801919020 sameAs 2801919020 @default.
• W2801919020 citedByCount "5" @default.
• W2801919020 countsByYear W28019190202020 @default.
• W2801919020 countsByYear W28019190202021 @default.
• W2801919020 countsByYear W28019190202023 @default.
• W2801919020 crossrefType "journal-article" @default.
• W2801919020 hasAuthorship W2801919020A5007803202 @default.
• W2801919020 hasAuthorship W2801919020A5018814025 @default.
• W2801919020 hasAuthorship W2801919020A5055838753 @default.
• W2801919020 hasAuthorship W2801919020A5072102359 @default.
• W2801919020 hasBestOaLocation W28019190201 @default.
• W2801919020 hasConcept C104317684 @default.
• W2801919020 hasConcept C105795698 @default.
• W2801919020 hasConcept C111919701 @default.
• W2801919020 hasConcept C124101348 @default.
• W2801919020 hasConcept C12590798 @default.
• W2801919020 hasConcept C127413603 @default.
• W2801919020 hasConcept C165005293 @default.
• W2801919020 hasConcept C170154142 @default.
• W2801919020 hasConcept C177264268 @default.
• W2801919020 hasConcept C18555067 @default.
• W2801919020 hasConcept C193244246 @default.
• W2801919020 hasConcept C199360897 @default.
• W2801919020 hasConcept C2776760102 @default.
• W2801919020 hasConcept C2984074130 @default.
• W2801919020 hasConcept C33923547 @default.
• W2801919020 hasConcept C41008148 @default.
• W2801919020 hasConcept C43126263 @default.
• W2801919020 hasConcept C459310 @default.
• W2801919020 hasConcept C55493867 @default.
• W2801919020 hasConcept C76155785 @default.
• W2801919020 hasConcept C86803240 @default.
• W2801919020 hasConceptScore W2801919020C104317684 @default.
• W2801919020 hasConceptScore W2801919020C105795698 @default.
• W2801919020 hasConceptScore W2801919020C111919701 @default.
• W2801919020 hasConceptScore W2801919020C124101348 @default.
• W2801919020 hasConceptScore W2801919020C12590798 @default.
• W2801919020 hasConceptScore W2801919020C127413603 @default.
• W2801919020 hasConceptScore W2801919020C165005293 @default.
• W2801919020 hasConceptScore W2801919020C170154142 @default.

• next