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• W2801929954 endingPage "e0195820" @default.
• W2801929954 startingPage "e0195820" @default.
• W2801929954 abstract "Collagen hydrogels are widely used for in-vitro experiments and tissue engineering applications. Their use has been extended due to their biocompatibility with cells and their capacity to mimic biological tissues; nevertheless their mechanical properties are not always optimal for these purposes. Hydrogels are formed by a network of polymer filaments embedded on an aqueous substrate and their mechanical properties are mainly defined by the filament network architecture and the individual filament properties. To increase properties of native collagen, such as stiffness or strain-stiffening, these networks can be modified by adding crosslinking agents that alter the network architecture, increasing the unions between filaments. In this work, we have investigated the effect of one crosslinking agent, transglutaminase, in collagen hydrogels with varying collagen concentration. We have observed a linear dependency of the gel rigidity on the collagen concentration. Moreover, the addition of transglutaminase has induced an earlier strain-stiffening of the collagen gels. In addition, to better understand the mechanical implications of collagen concentration and crosslinkers inclusion, we have adapted an existing computational model, based on the worm-like chain model (WLC), to reproduce the mechanical behavior of the collagen gels. With this model we can estimate the parameters of the biopolymer networks without more sophisticated techniques, such as image processing or network reconstruction, or, inversely, predict the mechanical properties of a defined collagen network." @default.
• W2801929954 created "2018-05-17" @default.
• W2801929954 creator A5029758603 @default.
• W2801929954 creator A5031402166 @default.
• W2801929954 creator A5085160702 @default.
• W2801929954 creator A5050300672 @default.
• W2801929954 date "2018-04-17" @default.
• W2801929954 modified "2023-10-12" @default.
• W2801929954 title "Combined experimental and computational characterization of crosslinked collagen-based hydrogels" @default.
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• W2801929954 cites W1892184508 @default.
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• W2801929954 cites W1965933207 @default.
• W2801929954 cites W1969293769 @default.
• W2801929954 cites W1969979316 @default.
• W2801929954 cites W1984048987 @default.
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• W2801929954 cites W2009009823 @default.
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• W2801929954 cites W2075866529 @default.
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• W2801929954 cites W2476542314 @default.
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• W2801929954 doi "https://doi.org/10.1371/journal.pone.0195820" @default.
• W2801929954 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5903660" @default.
• W2801929954 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29664953" @default.
• W2801929954 hasPublicationYear "2018" @default.
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