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- W2802014062 abstract "INTRODUCTION: To present two cases and review the literature on pregnant post-menopausal women. METHODS: Case # 1 was a 53 year old with a pregnancy achieved by advanced reproductive techniques (ART) and complicated with twin gestation and pre-eclampsia at 28 weeks. A cesarean delivery was performed. Her post-operative course was complicated by pulmonary edema, hyperglycemia, anemia requiring transfusion, and acute kidney injury. Case # 2 was a 50 year old with a pregnancy achieved by ART and complicated with Stage 1 breast cancer, gestational hypertension, hypothyroidism, glucose intolerance, and diverticulosis. She had a cesarean delivery at 37 weeks. Data bases were searched to identify studies reporting on women who achieved pregnancy after the age of 50 using ART. Studies were examined for demographics and pregnancy outcomes. RESULTS: 11 studies were identified reporting on a total of 1070 women 50 or older with successful ART pregnancies. The age range was 51 to 64. Singleton rate was 59% to 89%. Cesarean delivery rate was 67% to 100%. Antenatal maternal hospitalization was 40% to 48%. Gestational diabetes was 5% to 45%. Hypertension in pregnancy was 4% to 59%. Neonate intensive care admission was 11% to 15%. Neonatal death was 2.6%. One maternal death was reported. CONCLUSION: With the development of donor oocyte and ART, there have been an increased number of births in post-menopausal women. These pregnancies can have serious complications and require multidisciplinary approach for optimal outcomes. Our experience was consistent with published case reports and case series." @default.
- W2802014062 created "2018-05-17" @default.
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- W2802014062 date "2018-05-01" @default.
- W2802014062 modified "2023-09-26" @default.
- W2802014062 title "Pregnancy After 50: Presentation of Two Cases and a Review of the Literature [27H]" @default.
- W2802014062 doi "https://doi.org/10.1097/01.aog.0000533415.13129.5f" @default.
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