Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802034689> ?p ?o ?g. }
- W2802034689 endingPage "225" @default.
- W2802034689 startingPage "225" @default.
- W2802034689 abstract "Adenosine is a naturally occurring breakdown product of adenosine triphosphate and plays an important role in different physiological and pathological conditions. Adenosine also serves as an important trigger in ischemic and remote preconditioning and its release may impart cardioprotection. Exogenous administration of adenosine in the form of adenosine preconditioning may also protect heart from ischemia-reperfusion injury. Endogenous release of adenosine during ischemic/remote preconditioning or exogenous adenosine during pharmacological preconditioning activates adenosine receptors to activate plethora of mechanisms, which either independently or in association with one another may confer cardioprotection during ischemia-reperfusion injury. These mechanisms include activation of KATP channels, an increase in the levels of antioxidant enzymes, functional interaction with opioid receptors; increase in nitric oxide production; decrease in inflammation; activation of transient receptor potential vanilloid (TRPV) channels; activation of kinases such as protein kinase B (Akt), protein kinase C, tyrosine kinase, mitogen activated protein (MAP) kinases such as ERK 1/2, p38 MAP kinases and MAP kinase kinase (MEK 1) MMP. The present review discusses the role and mechanisms involved in adenosine preconditioning-induced cardioprotection." @default.
- W2802034689 created "2018-05-17" @default.
- W2802034689 creator A5011711095 @default.
- W2802034689 creator A5064947153 @default.
- W2802034689 creator A5069392805 @default.
- W2802034689 creator A5076750710 @default.
- W2802034689 date "2018-01-01" @default.
- W2802034689 modified "2023-09-24" @default.
- W2802034689 title "Mechanisms involved in adenosine pharmacological preconditioning-induced cardioprotection" @default.
- W2802034689 cites W1502900031 @default.
- W2802034689 cites W1551278092 @default.
- W2802034689 cites W1613004837 @default.
- W2802034689 cites W1776221901 @default.
- W2802034689 cites W1909713665 @default.
- W2802034689 cites W1964849562 @default.
- W2802034689 cites W1975942893 @default.
- W2802034689 cites W1978584900 @default.
- W2802034689 cites W1988131087 @default.
- W2802034689 cites W1990166821 @default.
- W2802034689 cites W1992696099 @default.
- W2802034689 cites W1996387284 @default.
- W2802034689 cites W1997328050 @default.
- W2802034689 cites W1998004255 @default.
- W2802034689 cites W1998976439 @default.
- W2802034689 cites W1999501161 @default.
- W2802034689 cites W2001266428 @default.
- W2802034689 cites W2010440482 @default.
- W2802034689 cites W2012447220 @default.
- W2802034689 cites W2018820823 @default.
- W2802034689 cites W2024378010 @default.
- W2802034689 cites W2027039921 @default.
- W2802034689 cites W2029490679 @default.
- W2802034689 cites W2030099655 @default.
- W2802034689 cites W2035321467 @default.
- W2802034689 cites W2038998112 @default.
- W2802034689 cites W2047189484 @default.
- W2802034689 cites W2048607034 @default.
- W2802034689 cites W2051777105 @default.
- W2802034689 cites W2057761726 @default.
- W2802034689 cites W2063646140 @default.
- W2802034689 cites W2074569502 @default.
- W2802034689 cites W2075900692 @default.
- W2802034689 cites W2082878444 @default.
- W2802034689 cites W2089047127 @default.
- W2802034689 cites W2091471938 @default.
- W2802034689 cites W2095596429 @default.
- W2802034689 cites W2107555224 @default.
- W2802034689 cites W2110678149 @default.
- W2802034689 cites W2127186576 @default.
- W2802034689 cites W2130121543 @default.
- W2802034689 cites W2130398556 @default.
- W2802034689 cites W2146217294 @default.
- W2802034689 cites W2147818768 @default.
- W2802034689 cites W2153221719 @default.
- W2802034689 cites W2156054021 @default.
- W2802034689 cites W2162026966 @default.
- W2802034689 cites W2163982472 @default.
- W2802034689 cites W2165129990 @default.
- W2802034689 cites W2169806115 @default.
- W2802034689 cites W2214067098 @default.
- W2802034689 cites W2272705881 @default.
- W2802034689 cites W2274026539 @default.
- W2802034689 cites W2295789515 @default.
- W2802034689 cites W2325574638 @default.
- W2802034689 cites W2327454468 @default.
- W2802034689 cites W2345747362 @default.
- W2802034689 cites W2346936342 @default.
- W2802034689 cites W2403452377 @default.
- W2802034689 cites W2485315891 @default.
- W2802034689 cites W2509282351 @default.
- W2802034689 cites W2534987268 @default.
- W2802034689 cites W2588685743 @default.
- W2802034689 cites W2605147208 @default.
- W2802034689 cites W2612057859 @default.
- W2802034689 cites W94173706 @default.
- W2802034689 cites W2739681005 @default.
- W2802034689 doi "https://doi.org/10.4196/kjpp.2018.22.3.225" @default.
- W2802034689 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5928336" @default.
- W2802034689 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29719445" @default.
- W2802034689 hasPublicationYear "2018" @default.
- W2802034689 type Work @default.
- W2802034689 sameAs 2802034689 @default.
- W2802034689 citedByCount "17" @default.
- W2802034689 countsByYear W28020346892019 @default.
- W2802034689 countsByYear W28020346892020 @default.
- W2802034689 countsByYear W28020346892021 @default.
- W2802034689 countsByYear W28020346892022 @default.
- W2802034689 crossrefType "journal-article" @default.
- W2802034689 hasAuthorship W2802034689A5011711095 @default.
- W2802034689 hasAuthorship W2802034689A5064947153 @default.
- W2802034689 hasAuthorship W2802034689A5069392805 @default.
- W2802034689 hasAuthorship W2802034689A5076750710 @default.
- W2802034689 hasBestOaLocation W28020346891 @default.
- W2802034689 hasConcept C126322002 @default.
- W2802034689 hasConcept C158424129 @default.
- W2802034689 hasConcept C170493617 @default.
- W2802034689 hasConcept C172590197 @default.
- W2802034689 hasConcept C182683403 @default.