Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802079282> ?p ?o ?g. }
- W2802079282 abstract "The stalks of Polygonum hydropiper L. (PHL) have been traditionally used in clinical practice for thousands of years in China to treat various inflammatory diseases. However, little research has been conducted to investigate the anti-inflammatory effects of PHL on TNBS-induced intestinal inflammation in rats. The aim of the present study was to investigate the anti-inflammatory effects and to explain the underlying mechanism of PHL on TNBS-induced intestinal inflammation in rats. PHL (125, 250, and 500 mg/kg) was given for 7 consecutive days to rats with intestinal inflammation induced by TNBS. Oral administration of an aqueous extract of a high dose of PHL (H- PHL ) significantly improved TNBS-induced symptoms such as the macroscopic score and histological examination. H- PHL treatment significantly ameliorated the activity of MPO and improved the GSH content. In addition, there was a downregulation of the TNBS-induced increase in the activity of iNOS and levels of Cox-2, TNF- α , and IL-1 β while the protein expression of NF- κ B was significantly unregulated after administration of H- PHL . The present findings suggested that H- PHL has a protective effect on experimental intestinal inflammation in rats and its anti-inflammatory effects are closely related to inhibition of NF- κ B signal pathways." @default.
- W2802079282 created "2018-05-17" @default.
- W2802079282 creator A5013524550 @default.
- W2802079282 creator A5056246750 @default.
- W2802079282 creator A5058554120 @default.
- W2802079282 creator A5065726947 @default.
- W2802079282 creator A5076699095 @default.
- W2802079282 creator A5085574199 @default.
- W2802079282 date "2018-01-01" @default.
- W2802079282 modified "2023-10-13" @default.
- W2802079282 title "Anti-Inflammatory Effects of an Extract of Polygonum hydropiper Stalks on 2,4,6-Trinitrobenzenesulphonic Acid-Induced Intestinal Inflammation in Rats by Inhibiting the NF-κB Pathway" @default.
- W2802079282 cites W1523941392 @default.
- W2802079282 cites W1900915098 @default.
- W2802079282 cites W194742946 @default.
- W2802079282 cites W1965745443 @default.
- W2802079282 cites W1967250455 @default.
- W2802079282 cites W1972987064 @default.
- W2802079282 cites W1985582210 @default.
- W2802079282 cites W1987418104 @default.
- W2802079282 cites W1991151307 @default.
- W2802079282 cites W1991364003 @default.
- W2802079282 cites W1993382405 @default.
- W2802079282 cites W1999812913 @default.
- W2802079282 cites W2002128907 @default.
- W2802079282 cites W2002554362 @default.
- W2802079282 cites W2007277298 @default.
- W2802079282 cites W2008854574 @default.
- W2802079282 cites W2016537283 @default.
- W2802079282 cites W2023627397 @default.
- W2802079282 cites W2030604116 @default.
- W2802079282 cites W2047957620 @default.
- W2802079282 cites W2058250733 @default.
- W2802079282 cites W2063611643 @default.
- W2802079282 cites W2066659580 @default.
- W2802079282 cites W2069348249 @default.
- W2802079282 cites W2070142972 @default.
- W2802079282 cites W2072427888 @default.
- W2802079282 cites W2073703119 @default.
- W2802079282 cites W2073938056 @default.
- W2802079282 cites W2077018765 @default.
- W2802079282 cites W2078263231 @default.
- W2802079282 cites W2079203240 @default.
- W2802079282 cites W2079827473 @default.
- W2802079282 cites W2082404102 @default.
- W2802079282 cites W2082439167 @default.
- W2802079282 cites W2084860737 @default.
- W2802079282 cites W2093647841 @default.
- W2802079282 cites W2101082371 @default.
- W2802079282 cites W2103979966 @default.
- W2802079282 cites W2106072534 @default.
- W2802079282 cites W2124711796 @default.
- W2802079282 cites W2127532535 @default.
- W2802079282 cites W2128977463 @default.
- W2802079282 cites W2143004652 @default.
- W2802079282 cites W2147410865 @default.
- W2802079282 cites W2155857041 @default.
- W2802079282 cites W2155960955 @default.
- W2802079282 cites W2157002193 @default.
- W2802079282 cites W2163788153 @default.
- W2802079282 cites W2168827049 @default.
- W2802079282 cites W2307712312 @default.
- W2802079282 cites W2329425965 @default.
- W2802079282 cites W2550223850 @default.
- W2802079282 cites W2576529584 @default.
- W2802079282 doi "https://doi.org/10.1155/2018/6029135" @default.
- W2802079282 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5964420" @default.
- W2802079282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29853790" @default.
- W2802079282 hasPublicationYear "2018" @default.
- W2802079282 type Work @default.
- W2802079282 sameAs 2802079282 @default.
- W2802079282 citedByCount "3" @default.
- W2802079282 countsByYear W28020792822021 @default.
- W2802079282 countsByYear W28020792822023 @default.
- W2802079282 crossrefType "journal-article" @default.
- W2802079282 hasAuthorship W2802079282A5013524550 @default.
- W2802079282 hasAuthorship W2802079282A5056246750 @default.
- W2802079282 hasAuthorship W2802079282A5058554120 @default.
- W2802079282 hasAuthorship W2802079282A5065726947 @default.
- W2802079282 hasAuthorship W2802079282A5076699095 @default.
- W2802079282 hasAuthorship W2802079282A5085574199 @default.
- W2802079282 hasBestOaLocation W28020792821 @default.
- W2802079282 hasConcept C104317684 @default.
- W2802079282 hasConcept C126322002 @default.
- W2802079282 hasConcept C127561419 @default.
- W2802079282 hasConcept C17991360 @default.
- W2802079282 hasConcept C181199279 @default.
- W2802079282 hasConcept C185592680 @default.
- W2802079282 hasConcept C203565725 @default.
- W2802079282 hasConcept C2776077704 @default.
- W2802079282 hasConcept C2776914184 @default.
- W2802079282 hasConcept C2777056448 @default.
- W2802079282 hasConcept C2777730290 @default.
- W2802079282 hasConcept C2779703632 @default.
- W2802079282 hasConcept C538909803 @default.
- W2802079282 hasConcept C55493867 @default.
- W2802079282 hasConcept C556039675 @default.
- W2802079282 hasConcept C71924100 @default.
- W2802079282 hasConcept C98274493 @default.
- W2802079282 hasConceptScore W2802079282C104317684 @default.
- W2802079282 hasConceptScore W2802079282C126322002 @default.