FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802176098> ?p ?o ?g. }

• W2802176098 endingPage "204" @default.
• W2802176098 startingPage "193" @default.
• W2802176098 abstract "Rhoptry proteins (ROPs) are involved in the different stages of Toxoplasma gondii (T. gondii) invasion and are also critical for survival within host cells. ROP8 is expressed in the early stages of infection and have a key role in the parasitophorous vacuole (PV) formation. In this paper, we have combined several bioinformatics online servers for immunogenicity prediction of ROP8 protein. In this study, several bioinformatics approaches were used to analyze the different aspects of ROP8 protein, including the physico-chemical properties, transmembrane domain, subcellular localization, secondary and tertiary structure, B and T-cell potential epitopes, and other important characteristics of this protein. The findings showed that ROP8 protein had 60 potential post-translational modification sites. Also, only one transmembrane domain was recognized for this protein. The secondary structure of ROP8 protein comprises 33.04% alpha-helix, 18.26% extended strand, and 48.70% random coil. Moreover, several potential B and T-cell epitopes were identified for ROP8. In addition, the obtained findings from antigenicity and allergenicity evaluation remarked that this protein is immunogenic and non-allergen. Based on the results of Ramachandran plot, 94.8%, 4.1%, and 1.1% of amino acid residues were incorporated in the favored, allowed, and outlier regions, respectively. This paper provides a foundation for further investigations, and laid a theoretical basis for the development of an appropriate vaccine against toxoplasmosis. More studies are needed experimentally using the ROP8 alone or in combination with other antigens in the future." @default.
• W2802176098 created "2018-05-17" @default.
• W2802176098 creator A5006720918 @default.
• W2802176098 creator A5038147641 @default.
• W2802176098 creator A5042957176 @default.
• W2802176098 creator A5050947101 @default.
• W2802176098 creator A5072366432 @default.
• W2802176098 date "2018-08-01" @default.
• W2802176098 modified "2023-10-15" @default.
• W2802176098 title "Bioinformatics analysis of ROP8 protein to improve vaccine design against Toxoplasma gondii" @default.
• W2802176098 cites W1491040459 @default.
• W2802176098 cites W1526839960 @default.
• W2802176098 cites W1881165596 @default.
• W2802176098 cites W1979715956 @default.
• W2802176098 cites W1993484262 @default.
• W2802176098 cites W1993568862 @default.
• W2802176098 cites W1997446599 @default.
• W2802176098 cites W1998047654 @default.
• W2802176098 cites W2002642825 @default.
• W2802176098 cites W2011640853 @default.
• W2802176098 cites W2031719384 @default.
• W2802176098 cites W2035014358 @default.
• W2802176098 cites W2048625606 @default.
• W2802176098 cites W2050263490 @default.
• W2802176098 cites W2055009787 @default.
• W2802176098 cites W2066391534 @default.
• W2802176098 cites W2066609648 @default.
• W2802176098 cites W2067003225 @default.
• W2802176098 cites W2070763276 @default.
• W2802176098 cites W2072708496 @default.
• W2802176098 cites W2074986801 @default.
• W2802176098 cites W2083157454 @default.
• W2802176098 cites W2084594144 @default.
• W2802176098 cites W2087202599 @default.
• W2802176098 cites W2097874743 @default.
• W2802176098 cites W2098182896 @default.
• W2802176098 cites W2100316154 @default.
• W2802176098 cites W2102023232 @default.
• W2802176098 cites W2102367710 @default.
• W2802176098 cites W2114241062 @default.
• W2802176098 cites W2118862527 @default.
• W2802176098 cites W2127595465 @default.
• W2802176098 cites W2128841444 @default.
• W2802176098 cites W2129434797 @default.
• W2802176098 cites W2131025240 @default.
• W2802176098 cites W2133458779 @default.
• W2802176098 cites W2139915497 @default.
• W2802176098 cites W2140400465 @default.
• W2802176098 cites W2141264786 @default.
• W2802176098 cites W2142788740 @default.
• W2802176098 cites W2159767366 @default.
• W2802176098 cites W2160397907 @default.
• W2802176098 cites W2168387989 @default.
• W2802176098 cites W2171295581 @default.
• W2802176098 cites W2172992695 @default.
• W2802176098 cites W2265594729 @default.
• W2802176098 cites W2294411093 @default.
• W2802176098 cites W2294487746 @default.
• W2802176098 cites W2314629239 @default.
• W2802176098 cites W2317746847 @default.
• W2802176098 cites W2329393210 @default.
• W2802176098 cites W2340326146 @default.
• W2802176098 cites W2340541205 @default.
• W2802176098 cites W2412810274 @default.
• W2802176098 cites W2424334291 @default.
• W2802176098 cites W2481586484 @default.
• W2802176098 cites W2534040426 @default.
• W2802176098 cites W2558126369 @default.
• W2802176098 cites W2584923474 @default.
• W2802176098 cites W2604190577 @default.
• W2802176098 cites W2620244386 @default.
• W2802176098 cites W2620565148 @default.
• W2802176098 cites W2724990448 @default.
• W2802176098 cites W2735259704 @default.
• W2802176098 cites W2738123315 @default.
• W2802176098 cites W2785781569 @default.
• W2802176098 cites W2792768023 @default.
• W2802176098 cites W2799758313 @default.
• W2802176098 cites W2800022116 @default.
• W2802176098 cites W2801243762 @default.
• W2802176098 doi "https://doi.org/10.1016/j.meegid.2018.04.033" @default.
• W2802176098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29705360" @default.
• W2802176098 hasPublicationYear "2018" @default.
• W2802176098 type Work @default.
• W2802176098 sameAs 2802176098 @default.
• W2802176098 citedByCount "38" @default.
• W2802176098 countsByYear W28021760982018 @default.
• W2802176098 countsByYear W28021760982019 @default.
• W2802176098 countsByYear W28021760982020 @default.
• W2802176098 countsByYear W28021760982021 @default.
• W2802176098 countsByYear W28021760982022 @default.
• W2802176098 countsByYear W28021760982023 @default.
• W2802176098 crossrefType "journal-article" @default.
• W2802176098 hasAuthorship W2802176098A5006720918 @default.
• W2802176098 hasAuthorship W2802176098A5038147641 @default.
• W2802176098 hasAuthorship W2802176098A5042957176 @default.
• W2802176098 hasAuthorship W2802176098A5050947101 @default.
• W2802176098 hasAuthorship W2802176098A5072366432 @default.

• next