Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802194826> ?p ?o ?g. }
- W2802194826 endingPage "554" @default.
- W2802194826 startingPage "547" @default.
- W2802194826 abstract "Hb G-Coushatta variant was reported from various populations' parts of the world such as Thai, Korea, Algeria, Thailand, China, Japan and Turkey. In our study, we aimed to discuss the possible historical relationships of the Hb G-Coushatta mutation with the possible migration routes of the world. For this purpose, associated haplotypes were determined using polymorphic loci in the beta globin gene cluster of hemoglobin G-Coushatta and normal populations in Denizli, Turkey.We performed statistical analysis such as haplotype analysis, Hardy-Weinberg equilibrium, measurement of genetic diversity and population differentiation parameters, analysis of molecular variance using F-statistics, historical-demographic analyses, mismatch distribution analysis of both populations and applied the test statistics in Arlequin ver. 3.5 software program.The diversity of haplotypes has been shown to indicate different genetic origins for two populations. However, AMOVA results, molecular diversity parameters and population demographic expansion times showed that the Hb G-Coushatta mutation develops on the normal population gene pool. Our estimated τ values showed the average time since the demographic expansion for normal and Hb G-Coushatta populations ranged from approximately 42,000 to 38,000 ybp, respectively.Our data suggest that Hb G-Coushatta population originate in normal population in Denizli, Turkey. These results support the hypothesis that the multiple origin of Hb G-Coushatta and indicate that mutation may have been triggered the formation of new variants on beta globin haplotypes." @default.
- W2802194826 created "2018-05-17" @default.
- W2802194826 creator A5020285616 @default.
- W2802194826 creator A5068303114 @default.
- W2802194826 creator A5071049024 @default.
- W2802194826 creator A5074714307 @default.
- W2802194826 date "2018-05-01" @default.
- W2802194826 modified "2023-10-12" @default.
- W2802194826 title "Estimating the age of Hb G-Coushatta [β22(B4)Glu→Ala] mutation by haplotypes of β-globin gene cluster in Denizli, Turkey" @default.
- W2802194826 cites W1632827427 @default.
- W2802194826 cites W1761250483 @default.
- W2802194826 cites W1768287364 @default.
- W2802194826 cites W1919772617 @default.
- W2802194826 cites W1969422397 @default.
- W2802194826 cites W1975249406 @default.
- W2802194826 cites W1979115933 @default.
- W2802194826 cites W1983832686 @default.
- W2802194826 cites W1986864617 @default.
- W2802194826 cites W1990074132 @default.
- W2802194826 cites W1990376432 @default.
- W2802194826 cites W2012893694 @default.
- W2802194826 cites W2045518901 @default.
- W2802194826 cites W2046062863 @default.
- W2802194826 cites W2056051495 @default.
- W2802194826 cites W2056940676 @default.
- W2802194826 cites W2089290332 @default.
- W2802194826 cites W2092405660 @default.
- W2802194826 cites W2096711345 @default.
- W2802194826 cites W2100444509 @default.
- W2802194826 cites W2112348586 @default.
- W2802194826 cites W2115837217 @default.
- W2802194826 cites W2119799171 @default.
- W2802194826 cites W2129283257 @default.
- W2802194826 cites W2132297696 @default.
- W2802194826 cites W2140784970 @default.
- W2802194826 cites W2146115284 @default.
- W2802194826 cites W2149354946 @default.
- W2802194826 cites W2153777689 @default.
- W2802194826 cites W2162512284 @default.
- W2802194826 cites W2181404150 @default.
- W2802194826 cites W2218056127 @default.
- W2802194826 cites W2287687285 @default.
- W2802194826 cites W2329823270 @default.
- W2802194826 cites W2412617688 @default.
- W2802194826 cites W2523323366 @default.
- W2802194826 cites W2802194826 @default.
- W2802194826 cites W93588716 @default.
- W2802194826 doi "https://doi.org/10.1002/mgg3.404" @default.
- W2802194826 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6081228" @default.
- W2802194826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29717566" @default.
- W2802194826 hasPublicationYear "2018" @default.
- W2802194826 type Work @default.
- W2802194826 sameAs 2802194826 @default.
- W2802194826 citedByCount "3" @default.
- W2802194826 countsByYear W28021948262022 @default.
- W2802194826 countsByYear W28021948262023 @default.
- W2802194826 crossrefType "journal-article" @default.
- W2802194826 hasAuthorship W2802194826A5020285616 @default.
- W2802194826 hasAuthorship W2802194826A5068303114 @default.
- W2802194826 hasAuthorship W2802194826A5071049024 @default.
- W2802194826 hasAuthorship W2802194826A5074714307 @default.
- W2802194826 hasBestOaLocation W28021948261 @default.
- W2802194826 hasConcept C104317684 @default.
- W2802194826 hasConcept C144024400 @default.
- W2802194826 hasConcept C149923435 @default.
- W2802194826 hasConcept C180754005 @default.
- W2802194826 hasConcept C197754878 @default.
- W2802194826 hasConcept C2778050382 @default.
- W2802194826 hasConcept C2908647359 @default.
- W2802194826 hasConcept C517289559 @default.
- W2802194826 hasConcept C54355233 @default.
- W2802194826 hasConcept C68873052 @default.
- W2802194826 hasConcept C81977670 @default.
- W2802194826 hasConcept C86803240 @default.
- W2802194826 hasConceptScore W2802194826C104317684 @default.
- W2802194826 hasConceptScore W2802194826C144024400 @default.
- W2802194826 hasConceptScore W2802194826C149923435 @default.
- W2802194826 hasConceptScore W2802194826C180754005 @default.
- W2802194826 hasConceptScore W2802194826C197754878 @default.
- W2802194826 hasConceptScore W2802194826C2778050382 @default.
- W2802194826 hasConceptScore W2802194826C2908647359 @default.
- W2802194826 hasConceptScore W2802194826C517289559 @default.
- W2802194826 hasConceptScore W2802194826C54355233 @default.
- W2802194826 hasConceptScore W2802194826C68873052 @default.
- W2802194826 hasConceptScore W2802194826C81977670 @default.
- W2802194826 hasConceptScore W2802194826C86803240 @default.
- W2802194826 hasIssue "4" @default.
- W2802194826 hasLocation W28021948261 @default.
- W2802194826 hasLocation W28021948262 @default.
- W2802194826 hasLocation W28021948263 @default.
- W2802194826 hasLocation W28021948264 @default.
- W2802194826 hasOpenAccess W2802194826 @default.
- W2802194826 hasPrimaryLocation W28021948261 @default.
- W2802194826 hasRelatedWork W1968992308 @default.
- W2802194826 hasRelatedWork W2060631033 @default.
- W2802194826 hasRelatedWork W2096421284 @default.
- W2802194826 hasRelatedWork W2348008017 @default.
- W2802194826 hasRelatedWork W2359113872 @default.