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- W2802227256 abstract "Abstract A liver fluke is a digenetic trematode parasitizing in the hepatic ducts of human beings or animals. Patients with liver fluke infection suffer from a series of hepatobiliary diseases. The prevalence of cholangiocarcinoma is significantly high in areas with a high incidence of clonorchiasis. A liver fluke is an important biocarcinogenic factor in the occurrence of cholangiocarcinoma. The secretory products of the body of this parasite and long-term mechanical stimulation induce continuous inflammation of the bile duct. Gene expression of the bile duct cells is imbalanced, leading to carcinogenesis of the bile duct. This article provides a summary of recent studies on the epidemiology, clinicopathology, and molecular biology of cholangiocarcinoma induced by liver fluke infection." @default.
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- W2802227256 date "2018-04-10" @default.
- W2802227256 modified "2023-09-26" @default.
- W2802227256 title "Research progress of cholangiocarcinoma induced by liver fluke infection" @default.
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- W2802227256 doi "https://doi.org/10.2478/ii-2018-0003" @default.
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