FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802254429> ?p ?o ?g. }

• W2802254429 endingPage "40" @default.
• W2802254429 startingPage "33" @default.
• W2802254429 abstract "The neural correlates of emotion perception have been shown to be significantly altered in schizophrenia (SCZ) patients as well as their healthy relatives, possibly reflecting genetic susceptibility to the disease. The aim of the study was to investigate the association between SCZ polygenic risk and brain activity whilst testing perception of multisensory, dynamic emotional stimuli. We created SCZ polygenic risk scores (PRS) for a sample of twenty-eight healthy individuals. The PRS was based on data from the Psychiatric Genomics Consortium and was used as a regressor score in the neuroimaging analysis. The results of a multivariate brain-behaviour analysis show that higher SCZ PRS are related to increased activity in brain regions critical for emotion during the perception of threatening (angry) emotions. These results suggest that individuals with higher SCZ PRS over-activate the neural correlates underlying emotion during perception of threat, perhaps due to an increased experience of fear or neural inefficiency in emotion-regulation areas. Moreover, over-recruitment of emotion regulation regions might function as a compensation to maintain normal emotion regulation during threat perception. If replicated in larger studies, these findings may have important implications for understanding the neurophysiological biomarkers relevant in SCZ." @default.
• W2802254429 created "2018-05-17" @default.
• W2802254429 creator A5040959615 @default.
• W2802254429 creator A5053284044 @default.
• W2802254429 creator A5063001924 @default.
• W2802254429 creator A5091225960 @default.
• W2802254429 date "2018-06-01" @default.
• W2802254429 modified "2023-10-12" @default.
• W2802254429 title "Association between schizophrenia polygenic risk and neural correlates of emotion perception" @default.
• W2802254429 cites W1533496174 @default.
• W2802254429 cites W1554844832 @default.
• W2802254429 cites W1822607073 @default.
• W2802254429 cites W1963525383 @default.
• W2802254429 cites W1971460888 @default.
• W2802254429 cites W1975427503 @default.
• W2802254429 cites W1980114220 @default.
• W2802254429 cites W1983805722 @default.
• W2802254429 cites W1991089689 @default.
• W2802254429 cites W2006884100 @default.
• W2802254429 cites W2010408890 @default.
• W2802254429 cites W2010852926 @default.
• W2802254429 cites W2013336473 @default.
• W2802254429 cites W2020663825 @default.
• W2802254429 cites W2028260332 @default.
• W2802254429 cites W2028905593 @default.
• W2802254429 cites W2029686664 @default.
• W2802254429 cites W2030589240 @default.
• W2802254429 cites W2031503422 @default.
• W2802254429 cites W2049586547 @default.
• W2802254429 cites W2050338112 @default.
• W2802254429 cites W2060501426 @default.
• W2802254429 cites W2063005891 @default.
• W2802254429 cites W2067533301 @default.
• W2802254429 cites W2076257270 @default.
• W2802254429 cites W2080524507 @default.
• W2802254429 cites W2088242772 @default.
• W2802254429 cites W2094267229 @default.
• W2802254429 cites W2102748276 @default.
• W2802254429 cites W2105910682 @default.
• W2802254429 cites W2106559434 @default.
• W2802254429 cites W2113494365 @default.
• W2802254429 cites W2114429947 @default.
• W2802254429 cites W2114985586 @default.
• W2802254429 cites W2116139029 @default.
• W2802254429 cites W2120136619 @default.
• W2802254429 cites W2125823313 @default.
• W2802254429 cites W2128325991 @default.
• W2802254429 cites W2133156861 @default.
• W2802254429 cites W2139776339 @default.
• W2802254429 cites W2152914367 @default.
• W2802254429 cites W2157084451 @default.
• W2802254429 cites W2157957708 @default.
• W2802254429 cites W2159580216 @default.
• W2802254429 cites W2165160891 @default.
• W2802254429 cites W2165707697 @default.
• W2802254429 cites W2166192198 @default.
• W2802254429 cites W2167474156 @default.
• W2802254429 cites W2169984324 @default.
• W2802254429 cites W2173331897 @default.
• W2802254429 cites W2261385605 @default.
• W2802254429 cites W2335728362 @default.
• W2802254429 cites W2342728110 @default.
• W2802254429 cites W2536245292 @default.
• W2802254429 doi "https://doi.org/10.1016/j.pscychresns.2018.04.005" @default.
• W2802254429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29723776" @default.
• W2802254429 hasPublicationYear "2018" @default.
• W2802254429 type Work @default.
• W2802254429 sameAs 2802254429 @default.
• W2802254429 citedByCount "8" @default.
• W2802254429 countsByYear W28022544292018 @default.
• W2802254429 countsByYear W28022544292019 @default.
• W2802254429 countsByYear W28022544292020 @default.
• W2802254429 countsByYear W28022544292021 @default.
• W2802254429 countsByYear W28022544292023 @default.
• W2802254429 crossrefType "journal-article" @default.
• W2802254429 hasAuthorship W2802254429A5040959615 @default.
• W2802254429 hasAuthorship W2802254429A5053284044 @default.
• W2802254429 hasAuthorship W2802254429A5063001924 @default.
• W2802254429 hasAuthorship W2802254429A5091225960 @default.
• W2802254429 hasBestOaLocation W28022544292 @default.
• W2802254429 hasConcept C104317684 @default.
• W2802254429 hasConcept C118552586 @default.
• W2802254429 hasConcept C129564537 @default.
• W2802254429 hasConcept C135763542 @default.
• W2802254429 hasConcept C142724271 @default.
• W2802254429 hasConcept C142853389 @default.
• W2802254429 hasConcept C152198750 @default.
• W2802254429 hasConcept C153209595 @default.
• W2802254429 hasConcept C15744967 @default.
• W2802254429 hasConcept C169760540 @default.
• W2802254429 hasConcept C169900460 @default.
• W2802254429 hasConcept C18183760 @default.
• W2802254429 hasConcept C26760741 @default.
• W2802254429 hasConcept C2776141551 @default.
• W2802254429 hasConcept C2776412080 @default.
• W2802254429 hasConcept C2779134260 @default.
• W2802254429 hasConcept C2993137441 @default.
• W2802254429 hasConcept C542102704 @default.

• next