Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802374811> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2802374811 endingPage "51" @default.
- W2802374811 startingPage "46" @default.
- W2802374811 abstract "This study explored whether the functional protein tyrosine phosphatase nonreceptor 22 (PTPN22) G788A (R263Q) polymorphism is associated with susceptibility to autoimmune diseases. A meta-analysis was conducted using 23 comparative studies with a total of 16,719 patients and 17,783 controls. The meta-analysis showed an association between the A allele of the PTPN22 G788A polymorphism and decreased risk of autoimmune diseases in all subjects (p < 0.001). Analysis after stratification by ethnicity indicated that the PTPN22 788A allele was significantly associated with autoimmune diseases in Europeans (p < 0.001) but not in Latin Americans. Meta-analysis by autoimmune disease type showed a significant negative association between the PTPN22 788A allele and systemic lupus erythematous (SLE) (p = 001), rheumatoid arthritis (RA) (p = 0.008), ulcerative colitis (UC) (p = 0.016), but not Crohn's disease (CD). A single study for each showed no association between the PTPN22 788A allele and systemic sclerosis, giant cell arteritis, Henoch-schonlein purpura, uveitis, and Grave's disease. This meta-analysis demonstrates that the PTPN22 G788A polymorphism confers protection against SLE, RA, and UC, supporting evidence of association of the PTPN22 gene with a subgroup of autoimmune diseases." @default.
- W2802374811 created "2018-05-17" @default.
- W2802374811 creator A5047843177 @default.
- W2802374811 creator A5058020714 @default.
- W2802374811 date "2018-04-30" @default.
- W2802374811 modified "2023-10-16" @default.
- W2802374811 title "Association between the functional PTPN22 G788A (R263Q) polymorphism and susceptibility to autoimmune diseases: A meta-analysis" @default.
- W2802374811 cites W163644054 @default.
- W2802374811 cites W1987677365 @default.
- W2802374811 cites W2007685911 @default.
- W2802374811 cites W2016319058 @default.
- W2802374811 cites W2018211135 @default.
- W2802374811 cites W2040274110 @default.
- W2802374811 cites W2094112728 @default.
- W2802374811 cites W2101239172 @default.
- W2802374811 cites W2119475255 @default.
- W2802374811 cites W2123958178 @default.
- W2802374811 cites W2142628971 @default.
- W2802374811 cites W2155102587 @default.
- W2802374811 cites W2165052240 @default.
- W2802374811 cites W256931825 @default.
- W2802374811 cites W2612318692 @default.
- W2802374811 doi "https://doi.org/10.14715/cmb/2018.64.5.7" @default.
- W2802374811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29729713" @default.
- W2802374811 hasPublicationYear "2018" @default.
- W2802374811 type Work @default.
- W2802374811 sameAs 2802374811 @default.
- W2802374811 citedByCount "10" @default.
- W2802374811 countsByYear W28023748112018 @default.
- W2802374811 countsByYear W28023748112019 @default.
- W2802374811 countsByYear W28023748112020 @default.
- W2802374811 countsByYear W28023748112021 @default.
- W2802374811 countsByYear W28023748112022 @default.
- W2802374811 crossrefType "journal-article" @default.
- W2802374811 hasAuthorship W2802374811A5047843177 @default.
- W2802374811 hasAuthorship W2802374811A5058020714 @default.
- W2802374811 hasBestOaLocation W28023748111 @default.
- W2802374811 hasConcept C104317684 @default.
- W2802374811 hasConcept C126322002 @default.
- W2802374811 hasConcept C135763542 @default.
- W2802374811 hasConcept C153209595 @default.
- W2802374811 hasConcept C159654299 @default.
- W2802374811 hasConcept C180754005 @default.
- W2802374811 hasConcept C203014093 @default.
- W2802374811 hasConcept C2777575956 @default.
- W2802374811 hasConcept C2779075594 @default.
- W2802374811 hasConcept C2779356809 @default.
- W2802374811 hasConcept C54355233 @default.
- W2802374811 hasConcept C71924100 @default.
- W2802374811 hasConcept C86803240 @default.
- W2802374811 hasConcept C95190672 @default.
- W2802374811 hasConceptScore W2802374811C104317684 @default.
- W2802374811 hasConceptScore W2802374811C126322002 @default.
- W2802374811 hasConceptScore W2802374811C135763542 @default.
- W2802374811 hasConceptScore W2802374811C153209595 @default.
- W2802374811 hasConceptScore W2802374811C159654299 @default.
- W2802374811 hasConceptScore W2802374811C180754005 @default.
- W2802374811 hasConceptScore W2802374811C203014093 @default.
- W2802374811 hasConceptScore W2802374811C2777575956 @default.
- W2802374811 hasConceptScore W2802374811C2779075594 @default.
- W2802374811 hasConceptScore W2802374811C2779356809 @default.
- W2802374811 hasConceptScore W2802374811C54355233 @default.
- W2802374811 hasConceptScore W2802374811C71924100 @default.
- W2802374811 hasConceptScore W2802374811C86803240 @default.
- W2802374811 hasConceptScore W2802374811C95190672 @default.
- W2802374811 hasIssue "5" @default.
- W2802374811 hasLocation W28023748111 @default.
- W2802374811 hasLocation W28023748112 @default.
- W2802374811 hasOpenAccess W2802374811 @default.
- W2802374811 hasPrimaryLocation W28023748111 @default.
- W2802374811 hasRelatedWork W2082406232 @default.
- W2802374811 hasRelatedWork W2129546463 @default.
- W2802374811 hasRelatedWork W2156283049 @default.
- W2802374811 hasRelatedWork W2316954211 @default.
- W2802374811 hasRelatedWork W2326094713 @default.
- W2802374811 hasRelatedWork W2427075784 @default.
- W2802374811 hasRelatedWork W2530314275 @default.
- W2802374811 hasRelatedWork W2617939361 @default.
- W2802374811 hasRelatedWork W2761967325 @default.
- W2802374811 hasRelatedWork W4210646529 @default.
- W2802374811 hasVolume "64" @default.
- W2802374811 isParatext "false" @default.
- W2802374811 isRetracted "false" @default.
- W2802374811 magId "2802374811" @default.
- W2802374811 workType "article" @default.