Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802393842> ?p ?o ?g. }
- W2802393842 endingPage "202" @default.
- W2802393842 startingPage "196" @default.
- W2802393842 abstract "microRNAs (miRNAs) are highly conserved, small non-coding endogenous molecule, and can participate in a variety of biological processes in organisms such as development, growth and immune response. Dual-Specificity Phosphatases (DUSPs) are enzymes that can remove phosphate groups from phosphatases. Research found that DUSP1 is an important molecule in the process of MAPK regulation. However, as a significant regulatory factor, the study of DUSP1 was very few in fish. Consequently, in this study, the regulatory role of miRNAs on DUSP1 has been verified through dual-luciferase reporter assay and western blotting analysis. Furethermore, we found that miR-375 mimics and pre-miR-375 plasmid can negatively regulate the target gene DUSP1 in miiuy croaker through combining with 3'untranslated region of DUSP1 gene. These experiment results directly indicate the negative regulatory function of miR-375 to DUSP1. Moreover, miR-375 can negatively regulate NF-κB signaling pathway via target to DUSP1. This study can increase our knowledge and help us to understand complexity of genomic and complex gene expression regulatory networks in teleost fish." @default.
- W2802393842 created "2018-05-17" @default.
- W2802393842 creator A5011103204 @default.
- W2802393842 creator A5017826971 @default.
- W2802393842 creator A5049407947 @default.
- W2802393842 creator A5059968285 @default.
- W2802393842 creator A5068239144 @default.
- W2802393842 creator A5077170267 @default.
- W2802393842 date "2018-09-01" @default.
- W2802393842 modified "2023-09-25" @default.
- W2802393842 title "microRNA-375 modulates the NF-κB pathway in miiuy croaker by targeting DUSP1 gene" @default.
- W2802393842 cites W144423133 @default.
- W2802393842 cites W1604827622 @default.
- W2802393842 cites W1958284284 @default.
- W2802393842 cites W1964162519 @default.
- W2802393842 cites W1992941735 @default.
- W2802393842 cites W2004840945 @default.
- W2802393842 cites W2031794136 @default.
- W2802393842 cites W2040191060 @default.
- W2802393842 cites W2045672814 @default.
- W2802393842 cites W2046138697 @default.
- W2802393842 cites W2061825298 @default.
- W2802393842 cites W2068961255 @default.
- W2802393842 cites W2107277218 @default.
- W2802393842 cites W2109341131 @default.
- W2802393842 cites W2111237266 @default.
- W2802393842 cites W2136991248 @default.
- W2802393842 cites W2146642335 @default.
- W2802393842 cites W2148712853 @default.
- W2802393842 cites W2158382482 @default.
- W2802393842 cites W2163199119 @default.
- W2802393842 cites W2169259339 @default.
- W2802393842 cites W2169873489 @default.
- W2802393842 cites W2169895170 @default.
- W2802393842 cites W2295914061 @default.
- W2802393842 cites W2324138891 @default.
- W2802393842 cites W2347066154 @default.
- W2802393842 cites W2410605730 @default.
- W2802393842 cites W2518953417 @default.
- W2802393842 cites W2520553714 @default.
- W2802393842 cites W2551505726 @default.
- W2802393842 cites W2552749772 @default.
- W2802393842 cites W2591124474 @default.
- W2802393842 cites W2597896379 @default.
- W2802393842 cites W2739381690 @default.
- W2802393842 cites W2754100860 @default.
- W2802393842 cites W4237011200 @default.
- W2802393842 doi "https://doi.org/10.1016/j.dci.2018.05.010" @default.
- W2802393842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29746983" @default.
- W2802393842 hasPublicationYear "2018" @default.
- W2802393842 type Work @default.
- W2802393842 sameAs 2802393842 @default.
- W2802393842 citedByCount "14" @default.
- W2802393842 countsByYear W28023938422018 @default.
- W2802393842 countsByYear W28023938422019 @default.
- W2802393842 countsByYear W28023938422020 @default.
- W2802393842 countsByYear W28023938422021 @default.
- W2802393842 countsByYear W28023938422022 @default.
- W2802393842 crossrefType "journal-article" @default.
- W2802393842 hasAuthorship W2802393842A5011103204 @default.
- W2802393842 hasAuthorship W2802393842A5017826971 @default.
- W2802393842 hasAuthorship W2802393842A5049407947 @default.
- W2802393842 hasAuthorship W2802393842A5059968285 @default.
- W2802393842 hasAuthorship W2802393842A5068239144 @default.
- W2802393842 hasAuthorship W2802393842A5077170267 @default.
- W2802393842 hasConcept C104317684 @default.
- W2802393842 hasConcept C11960822 @default.
- W2802393842 hasConcept C145059251 @default.
- W2802393842 hasConcept C150194340 @default.
- W2802393842 hasConcept C153911025 @default.
- W2802393842 hasConcept C161733203 @default.
- W2802393842 hasConcept C165864922 @default.
- W2802393842 hasConcept C178666793 @default.
- W2802393842 hasConcept C2780429522 @default.
- W2802393842 hasConcept C54355233 @default.
- W2802393842 hasConcept C86803240 @default.
- W2802393842 hasConcept C95444343 @default.
- W2802393842 hasConceptScore W2802393842C104317684 @default.
- W2802393842 hasConceptScore W2802393842C11960822 @default.
- W2802393842 hasConceptScore W2802393842C145059251 @default.
- W2802393842 hasConceptScore W2802393842C150194340 @default.
- W2802393842 hasConceptScore W2802393842C153911025 @default.
- W2802393842 hasConceptScore W2802393842C161733203 @default.
- W2802393842 hasConceptScore W2802393842C165864922 @default.
- W2802393842 hasConceptScore W2802393842C178666793 @default.
- W2802393842 hasConceptScore W2802393842C2780429522 @default.
- W2802393842 hasConceptScore W2802393842C54355233 @default.
- W2802393842 hasConceptScore W2802393842C86803240 @default.
- W2802393842 hasConceptScore W2802393842C95444343 @default.
- W2802393842 hasFunder F4320321001 @default.
- W2802393842 hasLocation W28023938421 @default.
- W2802393842 hasLocation W28023938422 @default.
- W2802393842 hasOpenAccess W2802393842 @default.
- W2802393842 hasPrimaryLocation W28023938421 @default.
- W2802393842 hasRelatedWork W166274801 @default.
- W2802393842 hasRelatedWork W1971980958 @default.
- W2802393842 hasRelatedWork W1988455047 @default.
- W2802393842 hasRelatedWork W2021208088 @default.