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- W2802545929 endingPage "683" @default.
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- W2802545929 abstract "Introduction: Since their initial description, perihilar cholangiocarcinoma (pCCA) has remained one of the more clinically challenging scenarios encountered by hepatobiliary surgeons. Surgery remains the only potentially curative therapy, but requires complex, technically demanding operations with high associated morbidity and mortality. Over the last several decades, advances in surgical technique and perioperative management have improved patient outcomes.Areas covered: Achievement of optimal outcomes requires a multidisciplinary approach from a team of providers with expertise in hepatobiliary and oncologic surgery, medical oncology, radiation oncology, and advanced gastroenterology. We herein report a comprehensive review on pCCA with an emphasis on surgical strategies and perioperative management.Expert commentary: Despite incremental improvements from advances in surgical technique and perioperative management, outcomes remain poor due to the aggressive systemic nature of this disease and the tendency for locoregional and distant recurrence. The marginal benefit observed with traditional systemic therapies continues to be a key weakness in current management. However, improved understanding of the genetic alterations and pathways that drive tumorigenesis has the potential to dramatically alter the way in which we care for these patients." @default.
- W2802545929 created "2018-05-17" @default.
- W2802545929 creator A5002070760 @default.
- W2802545929 creator A5006811200 @default.
- W2802545929 creator A5057140415 @default.
- W2802545929 date "2018-05-11" @default.
- W2802545929 modified "2023-09-26" @default.
- W2802545929 title "Surgical approaches for the treatment of perihilar cholangiocarcinoma" @default.
- W2802545929 cites W1513600835 @default.
- W2802545929 cites W1741750461 @default.
- W2802545929 cites W1823805089 @default.
- W2802545929 cites W1832149401 @default.
- W2802545929 cites W1890090785 @default.
- W2802545929 cites W1897971699 @default.
- W2802545929 cites W1948865892 @default.
- W2802545929 cites W1963498598 @default.
- W2802545929 cites W1969605779 @default.
- W2802545929 cites W1973268573 @default.
- W2802545929 cites W1974407986 @default.
- W2802545929 cites W1974517976 @default.
- W2802545929 cites W1980929835 @default.
- W2802545929 cites W1981938035 @default.
- W2802545929 cites W1983047804 @default.
- W2802545929 cites W1983402002 @default.
- W2802545929 cites W1990215937 @default.
- W2802545929 cites W1990729745 @default.
- W2802545929 cites W1990811990 @default.
- W2802545929 cites W1994938870 @default.
- W2802545929 cites W1996998286 @default.
- W2802545929 cites W2003300116 @default.
- W2802545929 cites W2009727299 @default.
- W2802545929 cites W2010502568 @default.
- W2802545929 cites W2010862158 @default.
- W2802545929 cites W2016933380 @default.
- W2802545929 cites W2017279958 @default.
- W2802545929 cites W2023201628 @default.
- W2802545929 cites W2030787026 @default.
- W2802545929 cites W2032324927 @default.
- W2802545929 cites W2033277476 @default.
- W2802545929 cites W2035254040 @default.
- W2802545929 cites W2042351056 @default.
- W2802545929 cites W2043881867 @default.
- W2802545929 cites W2054278834 @default.
- W2802545929 cites W2055712625 @default.
- W2802545929 cites W2057001801 @default.
- W2802545929 cites W2058268665 @default.
- W2802545929 cites W2058491683 @default.
- W2802545929 cites W2060499611 @default.
- W2802545929 cites W2061318890 @default.
- W2802545929 cites W2062127184 @default.
- W2802545929 cites W2062874237 @default.
- W2802545929 cites W2071182620 @default.
- W2802545929 cites W2073529084 @default.
- W2802545929 cites W2073726093 @default.
- W2802545929 cites W2075957912 @default.
- W2802545929 cites W2077373584 @default.
- W2802545929 cites W2077446805 @default.
- W2802545929 cites W2085306952 @default.
- W2802545929 cites W2086291140 @default.
- W2802545929 cites W2090026185 @default.
- W2802545929 cites W2092764866 @default.
- W2802545929 cites W2093273760 @default.
- W2802545929 cites W2094955701 @default.
- W2802545929 cites W2103437429 @default.
- W2802545929 cites W2104454548 @default.
- W2802545929 cites W2115261608 @default.
- W2802545929 cites W2135084091 @default.
- W2802545929 cites W2140140898 @default.
- W2802545929 cites W2146813692 @default.
- W2802545929 cites W2148899606 @default.
- W2802545929 cites W2153296763 @default.
- W2802545929 cites W2170228937 @default.
- W2802545929 cites W2222784674 @default.
- W2802545929 cites W2277585562 @default.
- W2802545929 cites W2317265960 @default.
- W2802545929 cites W2329439009 @default.
- W2802545929 cites W2333767446 @default.
- W2802545929 cites W2344161874 @default.
- W2802545929 cites W2410527001 @default.
- W2802545929 cites W2427373573 @default.
- W2802545929 cites W2467879510 @default.
- W2802545929 cites W2552752386 @default.
- W2802545929 cites W2560087117 @default.
- W2802545929 cites W2563368974 @default.
- W2802545929 cites W2593590814 @default.
- W2802545929 cites W2594543521 @default.
- W2802545929 cites W2594920397 @default.
- W2802545929 cites W2600363444 @default.
- W2802545929 cites W2602796098 @default.
- W2802545929 cites W2606095493 @default.
- W2802545929 cites W2724887518 @default.
- W2802545929 cites W2725911379 @default.
- W2802545929 cites W2727417117 @default.
- W2802545929 cites W2745824859 @default.
- W2802545929 cites W2763492611 @default.
- W2802545929 cites W2763637453 @default.
- W2802545929 cites W2770990707 @default.
- W2802545929 cites W2771304121 @default.