FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802637911> ?p ?o ?g. }

• W2802637911 endingPage "2614" @default.
• W2802637911 startingPage "2603" @default.
• W2802637911 abstract "The study aimed to screen microRNAs (miRNAs) that can be used for the early detection of colorectal cancer (CRC) based on differential expression of miRNA in serum.A three-stage study was designed with a total of 217 CRCs, 168 colorectal adenomas (CRAs), and 190 healthy controls (HCs). A quantitative reverse transcription polymerase chain reaction was performed in three stages. We screened 528 miRNA expression profiles in the sera of 40 patients (CRC n=20, CRA n=10, and HC n=10) for candidate miRNAs, then 210 serum samples (CRC n=90, CRA n=60, and HC n=60) were used for screening of candidate miRNAs. Three hundred and twenty-five independent individual samples (CRC n=107, CRA n=98, and HC n=120) were used to validate the most differentially-expressed miRNAs in the screening stage, and binary logistic regression was used in the validation stage. A receiver operating characteristic curve was drawn to evaluate the diagnostic accuracy.A 5-serum miRNA panel (miRNA-1246, miRNA-202-3p, miRNA-21-3p, miRNA-1229-3p, and miRNA-532-3p) effectively distinguished CRCs from HCs with 91.6% sensitivity and 91.7% specificity. The area under the curve (AUC) was 0.960 (95% confidence interval [CI]: 0.937-0.983). In addition, the panel also accurately distinguished CRCs from CRAs with 94.4% sensitivity and 84.7% specificity. The AUC was 0.951 (95% CI: 0.922-0.980).Our 5-serum miRNA panel accurately distinguished CRCs from CRAs and HCs with high sensitivity and specificity. The 5-serum miRNA panel may be a promising prospect for application as a nonintrusive and inexpensive method for the early detection of CRC." @default.
• W2802637911 created "2018-05-17" @default.
• W2802637911 creator A5007453059 @default.
• W2802637911 creator A5009191234 @default.
• W2802637911 creator A5011287020 @default.
• W2802637911 creator A5018170379 @default.
• W2802637911 creator A5020397376 @default.
• W2802637911 creator A5033062533 @default.
• W2802637911 creator A5044265859 @default.
• W2802637911 creator A5048489681 @default.
• W2802637911 date "2018-05-01" @default.
• W2802637911 modified "2023-09-25" @default.
• W2802637911 title "A 5-serum miRNA panel for the early detection of colorectal cancer" @default.
• W2802637911 cites W135371020 @default.
• W2802637911 cites W1703092991 @default.
• W2802637911 cites W1766127718 @default.
• W2802637911 cites W1965296962 @default.
• W2802637911 cites W1971343080 @default.
• W2802637911 cites W1975490039 @default.
• W2802637911 cites W1985213644 @default.
• W2802637911 cites W1992497862 @default.
• W2802637911 cites W1993850432 @default.
• W2802637911 cites W1995320913 @default.
• W2802637911 cites W1997845584 @default.
• W2802637911 cites W2002995168 @default.
• W2802637911 cites W2015046812 @default.
• W2802637911 cites W2015419250 @default.
• W2802637911 cites W2017611405 @default.
• W2802637911 cites W2024206172 @default.
• W2802637911 cites W2042757100 @default.
• W2802637911 cites W2048984063 @default.
• W2802637911 cites W2050899028 @default.
• W2802637911 cites W2051968829 @default.
• W2802637911 cites W2055313665 @default.
• W2802637911 cites W2071201826 @default.
• W2802637911 cites W2072399375 @default.
• W2802637911 cites W2086164560 @default.
• W2802637911 cites W2093478617 @default.
• W2802637911 cites W2097233439 @default.
• W2802637911 cites W2097471121 @default.
• W2802637911 cites W2105549148 @default.
• W2802637911 cites W2115093090 @default.
• W2802637911 cites W2130979840 @default.
• W2802637911 cites W2133587587 @default.
• W2802637911 cites W2135810600 @default.
• W2802637911 cites W2139528114 @default.
• W2802637911 cites W2139718333 @default.
• W2802637911 cites W2140226029 @default.
• W2802637911 cites W2140245250 @default.
• W2802637911 cites W2149240812 @default.
• W2802637911 cites W2167557255 @default.
• W2802637911 cites W2264524371 @default.
• W2802637911 cites W2272984102 @default.
• W2802637911 cites W2324080174 @default.
• W2802637911 cites W2326264847 @default.
• W2802637911 cites W2338315908 @default.
• W2802637911 cites W2413737165 @default.
• W2802637911 cites W2514067963 @default.
• W2802637911 cites W2564450937 @default.
• W2802637911 cites W2585895970 @default.
• W2802637911 cites W2586466595 @default.
• W2802637911 cites W2597632520 @default.
• W2802637911 cites W2597872842 @default.
• W2802637911 cites W2699220065 @default.
• W2802637911 cites W3150339341 @default.
• W2802637911 doi "https://doi.org/10.2147/ott.s153535" @default.
• W2802637911 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5951214" @default.
• W2802637911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29780253" @default.
• W2802637911 hasPublicationYear "2018" @default.
• W2802637911 type Work @default.
• W2802637911 sameAs 2802637911 @default.
• W2802637911 citedByCount "26" @default.
• W2802637911 countsByYear W28026379112018 @default.
• W2802637911 countsByYear W28026379112019 @default.
• W2802637911 countsByYear W28026379112020 @default.
• W2802637911 countsByYear W28026379112021 @default.
• W2802637911 countsByYear W28026379112022 @default.
• W2802637911 countsByYear W28026379112023 @default.
• W2802637911 crossrefType "journal-article" @default.
• W2802637911 hasAuthorship W2802637911A5007453059 @default.
• W2802637911 hasAuthorship W2802637911A5009191234 @default.
• W2802637911 hasAuthorship W2802637911A5011287020 @default.
• W2802637911 hasAuthorship W2802637911A5018170379 @default.
• W2802637911 hasAuthorship W2802637911A5020397376 @default.
• W2802637911 hasAuthorship W2802637911A5033062533 @default.
• W2802637911 hasAuthorship W2802637911A5044265859 @default.
• W2802637911 hasAuthorship W2802637911A5048489681 @default.
• W2802637911 hasBestOaLocation W28026379111 @default.
• W2802637911 hasConcept C104317684 @default.
• W2802637911 hasConcept C112705442 @default.
• W2802637911 hasConcept C121608353 @default.
• W2802637911 hasConcept C126322002 @default.
• W2802637911 hasConcept C143998085 @default.
• W2802637911 hasConcept C145059251 @default.
• W2802637911 hasConcept C146357865 @default.
• W2802637911 hasConcept C151730666 @default.
• W2802637911 hasConcept C151956035 @default.
• W2802637911 hasConcept C3020225094 @default.

• next