Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802670298> ?p ?o ?g. }
- W2802670298 endingPage "1057.e9" @default.
- W2802670298 startingPage "1045" @default.
- W2802670298 abstract "Ependymal cells are multi-ciliated cells that form the brain’s ventricular epithelium and a niche for neural stem cells (NSCs) in the ventricular-subventricular zone (V-SVZ). In addition, ependymal cells are suggested to be latent NSCs with a capacity to acquire neurogenic function. This remains highly controversial due to a lack of prospective in vivo labeling techniques that can effectively distinguish ependymal cells from neighboring V-SVZ NSCs. We describe a transgenic system that allows for targeted labeling of ependymal cells within the V-SVZ. Single-cell RNA-seq revealed that ependymal cells are enriched for cilia-related genes and share several stem-cell-associated genes with neural stem or progenitors. Under in vivo and in vitro neural-stem- or progenitor-stimulating environments, ependymal cells failed to demonstrate any suggestion of latent neural-stem-cell function. These findings suggest remarkable stability of ependymal cell function and provide fundamental insights into the molecular signature of the V-SVZ niche." @default.
- W2802670298 created "2018-05-17" @default.
- W2802670298 creator A5009861123 @default.
- W2802670298 creator A5022929963 @default.
- W2802670298 creator A5035135990 @default.
- W2802670298 creator A5036733857 @default.
- W2802670298 creator A5071787989 @default.
- W2802670298 creator A5074478086 @default.
- W2802670298 creator A5079997009 @default.
- W2802670298 creator A5081661242 @default.
- W2802670298 creator A5084242333 @default.
- W2802670298 date "2018-05-01" @default.
- W2802670298 modified "2023-10-09" @default.
- W2802670298 title "Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function" @default.
- W2802670298 cites W1502896205 @default.
- W2802670298 cites W1569136508 @default.
- W2802670298 cites W1617074755 @default.
- W2802670298 cites W1666901150 @default.
- W2802670298 cites W1964417952 @default.
- W2802670298 cites W1967912020 @default.
- W2802670298 cites W1976954026 @default.
- W2802670298 cites W1979283544 @default.
- W2802670298 cites W1988896202 @default.
- W2802670298 cites W1994938808 @default.
- W2802670298 cites W2009953822 @default.
- W2802670298 cites W2013485257 @default.
- W2802670298 cites W2026598324 @default.
- W2802670298 cites W2031482209 @default.
- W2802670298 cites W2031825750 @default.
- W2802670298 cites W2036785515 @default.
- W2802670298 cites W2047678214 @default.
- W2802670298 cites W2048430961 @default.
- W2802670298 cites W2048518917 @default.
- W2802670298 cites W2055561480 @default.
- W2802670298 cites W2057179701 @default.
- W2802670298 cites W2065970275 @default.
- W2802670298 cites W2102212449 @default.
- W2802670298 cites W2104719009 @default.
- W2802670298 cites W2108340830 @default.
- W2802670298 cites W2109838864 @default.
- W2802670298 cites W2112958657 @default.
- W2802670298 cites W2113992254 @default.
- W2802670298 cites W2114870653 @default.
- W2802670298 cites W2146417573 @default.
- W2802670298 cites W2150056436 @default.
- W2802670298 cites W2156354373 @default.
- W2802670298 cites W2165867905 @default.
- W2802670298 cites W2273101790 @default.
- W2802670298 cites W2285174330 @default.
- W2802670298 cites W2300048866 @default.
- W2802670298 cites W2319605272 @default.
- W2802670298 cites W2441910567 @default.
- W2802670298 cites W2570474222 @default.
- W2802670298 cites W2578839378 @default.
- W2802670298 cites W2604225185 @default.
- W2802670298 cites W2806391435 @default.
- W2802670298 cites W2951506174 @default.
- W2802670298 doi "https://doi.org/10.1016/j.cell.2018.03.063" @default.
- W2802670298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29727663" @default.
- W2802670298 hasPublicationYear "2018" @default.
- W2802670298 type Work @default.
- W2802670298 sameAs 2802670298 @default.
- W2802670298 citedByCount "131" @default.
- W2802670298 countsByYear W28026702982018 @default.
- W2802670298 countsByYear W28026702982019 @default.
- W2802670298 countsByYear W28026702982020 @default.
- W2802670298 countsByYear W28026702982021 @default.
- W2802670298 countsByYear W28026702982022 @default.
- W2802670298 countsByYear W28026702982023 @default.
- W2802670298 crossrefType "journal-article" @default.
- W2802670298 hasAuthorship W2802670298A5009861123 @default.
- W2802670298 hasAuthorship W2802670298A5022929963 @default.
- W2802670298 hasAuthorship W2802670298A5035135990 @default.
- W2802670298 hasAuthorship W2802670298A5036733857 @default.
- W2802670298 hasAuthorship W2802670298A5071787989 @default.
- W2802670298 hasAuthorship W2802670298A5074478086 @default.
- W2802670298 hasAuthorship W2802670298A5079997009 @default.
- W2802670298 hasAuthorship W2802670298A5081661242 @default.
- W2802670298 hasAuthorship W2802670298A5084242333 @default.
- W2802670298 hasBestOaLocation W28026702981 @default.
- W2802670298 hasConcept C136834591 @default.
- W2802670298 hasConcept C169760540 @default.
- W2802670298 hasConcept C201750760 @default.
- W2802670298 hasConcept C2777542384 @default.
- W2802670298 hasConcept C28328180 @default.
- W2802670298 hasConcept C2909073510 @default.
- W2802670298 hasConcept C529278444 @default.
- W2802670298 hasConcept C86803240 @default.
- W2802670298 hasConcept C95444343 @default.
- W2802670298 hasConceptScore W2802670298C136834591 @default.
- W2802670298 hasConceptScore W2802670298C169760540 @default.
- W2802670298 hasConceptScore W2802670298C201750760 @default.
- W2802670298 hasConceptScore W2802670298C2777542384 @default.
- W2802670298 hasConceptScore W2802670298C28328180 @default.
- W2802670298 hasConceptScore W2802670298C2909073510 @default.
- W2802670298 hasConceptScore W2802670298C529278444 @default.
- W2802670298 hasConceptScore W2802670298C86803240 @default.
- W2802670298 hasConceptScore W2802670298C95444343 @default.