FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2802865963> ?p ?o ?g. }

• W2802865963 abstract "Malaria mosquitoes have had a remarkable stability in the number of chromosomes in their karyotype (2n = 6) during 100 million years of evolution. Moreover, autosomal arms were assumed to maintain their integrity even if their associations with each other changed via whole-arm translocations. Here we use high-coverage comparative physical genome mapping of three Anopheles species to test the extent of evolutionary conservation of chromosomal arms in malaria mosquitoes. In this study, we developed a physical genome map for Anopheles atroparvus, one of the dominant malaria vectors in Europe. Using fluorescence in situ hybridization (FISH) of DNA probes with the ovarian nurse cell polytene chromosomes and synteny comparison, we anchored 56 genomic scaffolds to the An. atroparvus chromosomes. The obtained physical map represents 89.6% of the An. atroparvus genome. This genome has the second highest mapping coverage among Anophelinae assemblies after An. albimanus, which has 98.2% of the genome assigned to its chromosomes. A comparison of the An. atroparvus, An. albimanus, and An. gambiae genomes identified partial-arm translocations between the autosomal arms that break down the integrity of chromosome elements in evolution affecting the structure of the genetic material in the pericentromeric regions. Unlike An. atroparvus and An. albimanus, all chromosome elements of An. gambiae are fully syntenic with chromosome elements of the putative ancestral Anopheles karyotype. We also detected nonrandom distribution of large conserved synteny blocks and confirmed a higher rate of inversion fixation in the X chromosome compared with autosomes. Our study demonstrates the power of physical mapping for understanding the genome evolution in malaria mosquitoes. The results indicate that syntenic relationships among chromosome elements of Anopheles species have not been fully preserved because of multiple partial-arm translocations." @default.
• W2802865963 created "2018-05-17" @default.
• W2802865963 creator A5000071521 @default.
• W2802865963 creator A5011809742 @default.
• W2802865963 creator A5048174967 @default.
• W2802865963 creator A5068058046 @default.
• W2802865963 creator A5082163929 @default.
• W2802865963 date "2018-04-23" @default.
• W2802865963 modified "2023-10-06" @default.
• W2802865963 title "Partial-arm translocations in evolution of malaria mosquitoes revealed by high-coverage physical mapping of the Anopheles atroparvus genome" @default.
• W2802865963 cites W1506109861 @default.
• W2802865963 cites W1510878634 @default.
• W2802865963 cites W1545585374 @default.
• W2802865963 cites W1824226376 @default.
• W2802865963 cites W1859117663 @default.
• W2802865963 cites W1901505426 @default.
• W2802865963 cites W1935830688 @default.
• W2802865963 cites W1965403600 @default.
• W2802865963 cites W1976445111 @default.
• W2802865963 cites W1980620193 @default.
• W2802865963 cites W1986009232 @default.
• W2802865963 cites W1986495805 @default.
• W2802865963 cites W1989037221 @default.
• W2802865963 cites W2000399230 @default.
• W2802865963 cites W2007025047 @default.
• W2802865963 cites W2007888986 @default.
• W2802865963 cites W2016660771 @default.
• W2802865963 cites W2022651039 @default.
• W2802865963 cites W2025653272 @default.
• W2802865963 cites W2025720209 @default.
• W2802865963 cites W2027979457 @default.
• W2802865963 cites W2030207286 @default.
• W2802865963 cites W2049058980 @default.
• W2802865963 cites W2057857382 @default.
• W2802865963 cites W2090002702 @default.
• W2802865963 cites W2092882875 @default.
• W2802865963 cites W2102706191 @default.
• W2802865963 cites W2104574614 @default.
• W2802865963 cites W2108537834 @default.
• W2802865963 cites W2108876013 @default.
• W2802865963 cites W2121139063 @default.
• W2802865963 cites W2126897547 @default.
• W2802865963 cites W2131400772 @default.
• W2802865963 cites W2133090982 @default.
• W2802865963 cites W2135266373 @default.
• W2802865963 cites W2135589046 @default.
• W2802865963 cites W2136093018 @default.
• W2802865963 cites W2136104403 @default.
• W2802865963 cites W2136155713 @default.
• W2802865963 cites W2143420603 @default.
• W2802865963 cites W2144328273 @default.
• W2802865963 cites W2145968299 @default.
• W2802865963 cites W2166231658 @default.
• W2802865963 cites W2168622113 @default.
• W2802865963 cites W2170471361 @default.
• W2802865963 cites W2171397799 @default.
• W2802865963 cites W2283708125 @default.
• W2802865963 cites W2561965821 @default.
• W2802865963 cites W2581259096 @default.
• W2802865963 cites W2621418721 @default.
• W2802865963 cites W271138209 @default.
• W2802865963 cites W338402631 @default.
• W2802865963 cites W77154934 @default.
• W2802865963 doi "https://doi.org/10.1186/s12864-018-4663-4" @default.
• W2802865963 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5914054" @default.
• W2802865963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29688842" @default.
• W2802865963 hasPublicationYear "2018" @default.
• W2802865963 type Work @default.
• W2802865963 sameAs 2802865963 @default.
• W2802865963 citedByCount "17" @default.
• W2802865963 countsByYear W28028659632018 @default.
• W2802865963 countsByYear W28028659632019 @default.
• W2802865963 countsByYear W28028659632020 @default.
• W2802865963 countsByYear W28028659632021 @default.
• W2802865963 countsByYear W28028659632022 @default.
• W2802865963 countsByYear W28028659632023 @default.
• W2802865963 crossrefType "journal-article" @default.
• W2802865963 hasAuthorship W2802865963A5000071521 @default.
• W2802865963 hasAuthorship W2802865963A5011809742 @default.
• W2802865963 hasAuthorship W2802865963A5048174967 @default.
• W2802865963 hasAuthorship W2802865963A5068058046 @default.
• W2802865963 hasAuthorship W2802865963A5082163929 @default.
• W2802865963 hasBestOaLocation W28028659631 @default.
• W2802865963 hasConcept C104317684 @default.
• W2802865963 hasConcept C141231307 @default.
• W2802865963 hasConcept C203014093 @default.
• W2802865963 hasConcept C2776802408 @default.
• W2802865963 hasConcept C2778048844 @default.
• W2802865963 hasConcept C2779798688 @default.
• W2802865963 hasConcept C2781375639 @default.
• W2802865963 hasConcept C30481170 @default.
• W2802865963 hasConcept C51423104 @default.
• W2802865963 hasConcept C53226629 @default.
• W2802865963 hasConcept C53702515 @default.
• W2802865963 hasConcept C54355233 @default.
• W2802865963 hasConcept C78458016 @default.
• W2802865963 hasConcept C86803240 @default.
• W2802865963 hasConceptScore W2802865963C104317684 @default.
• W2802865963 hasConceptScore W2802865963C141231307 @default.
• W2802865963 hasConceptScore W2802865963C203014093 @default.

• next