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- W2802912494 abstract "Oral leukoplakia is one of the most common oral premalignant disorder. The classical evaluation through tissue biopsy is not always valid to evaluate the risk of malignization.RT-qPCR was performed on 47 blood samples (21 patients with leukoplakia, 2 with oral squamous cell carcinoma (OSCC), and 24 healthy patients) and on 11 tissue samples (3 leukoplakia, 4 OSCC, and 4 samples of healthy tissue).There are significant differences in expression between the different groups (F = 4.057, p = .006). The Duncan post hoc test shows that the only group that differentiates is the tumour tissue. Using Wilcoxon test, different covariables of patients with leukoplakia were analysed with respect to the group of healthy patients and no significant differences were observed.The diagnostic route through liquid biopsy has not been conclusive in this study, but there are significant differences in the levels analysed in the different tissue samples." @default.
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- W2802912494 date "2018-01-01" @default.
- W2802912494 modified "2023-09-26" @default.
- W2802912494 title "Determination and diagnostic value of <i>CA9</i> mRNA in peripheral blood of patients with oral leukoplakia" @default.
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- W2802912494 doi "https://doi.org/10.1080/14756366.2018.1466120" @default.
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