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- W2802962217 abstract "Abstract Cortical computation is distributed across multiple areas of the cortex by networks of reciprocal connectivity. However, how such connectivity contributes to the communication between the connected areas is not clear. In this study, we examine the communication between sensory and motor cortices. We develop an eye movement task in mice and combine it with optogenetic suppression and two-photon calcium imaging techniques. We identify a small region in the secondary motor cortex (MO s ) that controls eye movements and reciprocally connects with a rostrolateral part of the higher visual areas (V RL/A/AL ). These two regions encode both motor signals and visual information; however, the information flow between the regions depends on the direction of the connectivity: motor information is conveyed preferentially from the MO s to the V RL/A/AL , and sensory information is transferred primarily in the opposite direction. We propose that reciprocal connectivity streamlines information flow, enhancing the computational capacity of a distributed network." @default.
- W2802962217 created "2018-05-17" @default.
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- W2802962217 date "2018-01-23" @default.
- W2802962217 modified "2023-10-18" @default.
- W2802962217 title "Streamlined sensory motor communication through cortical reciprocal connectivity in a visually guided eye movement task" @default.
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- W2802962217 doi "https://doi.org/10.1038/s41467-017-02501-4" @default.
- W2802962217 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5780522" @default.
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- W2802962217 hasPublicationYear "2018" @default.
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