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• W2802972871 abstract "Pantoea vagans , a gram-negative bacterium from the genus Pantoea and family Enterobacteriaceae , is present in various natural environments and considered to be plant endophytes. We isolated the Pantoea vagans PV989 strain from the clinic and sequenced its whole genome. Besides a chromosome DNA molecule, it also harboured three large plasmids. A comparative genomics analysis was performed for the smallest plasmid, pPV989-94. It can be divided into four regions, including three conservative regions related to replication (R1), transfer conjugation (R2), and transfer leading (R3), and one variable region (R4). Further analysis showed that pPV989-94 is most similar to plasmids LA637P2 and pEA68 of Erwinia amylovora strains isolated from fruit trees. These three plasmids share three conservative regions (R1, R2, and R3). Interestingly, a fragment (R4<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:msup><mml:mrow /><mml:mrow><mml:mo>′</mml:mo></mml:mrow></mml:msup></mml:math>) in R4, mediated by phage integrase and phage integrase family site-specific recombinase and encoding 9 genes related to glycometabolism, resistance, and DNA repair, was unique in pPV989-94. Homologues of R4<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:msup><mml:mrow /><mml:mrow><mml:mo>′</mml:mo></mml:mrow></mml:msup></mml:math>were found in other plasmids or chromosomes, suggesting that horizontal gene transfer (HGT) occurred among different bacteria of various species or genera. The acquired functional genes may play important roles in the adaptation of bacteria to different hosts or environmental conditions." @default.
• W2802972871 created "2018-05-17" @default.
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• W2802972871 date "2018-01-01" @default.
• W2802972871 modified "2023-10-16" @default.
• W2802972871 title "Comparative Genomics Analysis of Plasmid pPV989-94 from a Clinical Isolate ofPantoea vagansPV989" @default.
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• W2802972871 doi "https://doi.org/10.1155/2018/1242819" @default.
• W2802972871 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5971314" @default.
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