Matches in SemOpenAlex for { <https://semopenalex.org/work/W2803022162> ?p ?o ?g. }
- W2803022162 abstract "The aim of this study was to assess the outcomes of remission induction in patients with IgG4-related disease (IgG4-RD) in our cohort, and to investigate the characteristics, prognosis, and risk factors in the patients failed of remission induction.We prospectively enrolled 215 newly diagnosed patients with IgG4-RD, who were initially treated with glucocorticoid (GC) alone or in combination with immunosuppressive agents (IM), and had at least 6 months of follow up. The therapeutic goals of remission induction were defined as fulfilling each of the following after the 6-month remission induction stage: (1) ≥ 50% decline in the IgG4-RD responder index (RI); (2) GC tapered to maintenance dose; and (3) no relapse during GC tapering. The patients not achieving the therapeutic goals were considered to have failed of remission induction.There were 26 patients in our cohort who failed of remission induction, including 16 (20.8%) on GC monotherapy, and 10 (7.2%) on combination therapy comprising GC and IM. The lacrimal gland and lung were most common sites of remission induction failure. Among the patients who relapsed during remission induction stage, 52.9% had secondary relapse during follow-up. Eosinophilia, higher baseline RI, more than five organs involved and dacryoadenitis were risk factors for remission induction failure with GC monotherapy, and the incidence of remission induction failure was 71.4% in the patients with more than three risk factors. After 6-month treatment, the patients who failed of remission induction had significantly higher erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and IgG4.In our cohort, 20.8% of patients failed of remission induction with GC monotherapy, while 7.2% of patients failed of remission induction with combination therapy comprising GC and IM." @default.
- W2803022162 created "2018-05-17" @default.
- W2803022162 creator A5012208859 @default.
- W2803022162 creator A5016622484 @default.
- W2803022162 creator A5024232551 @default.
- W2803022162 creator A5026841517 @default.
- W2803022162 creator A5027079857 @default.
- W2803022162 creator A5034806661 @default.
- W2803022162 creator A5048663075 @default.
- W2803022162 creator A5058333204 @default.
- W2803022162 creator A5073523669 @default.
- W2803022162 creator A5082138222 @default.
- W2803022162 creator A5090435133 @default.
- W2803022162 date "2018-04-10" @default.
- W2803022162 modified "2023-10-15" @default.
- W2803022162 title "Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4-related disease: a prospective study of 215 patients" @default.
- W2803022162 cites W1135220358 @default.
- W2803022162 cites W1853735554 @default.
- W2803022162 cites W1934919943 @default.
- W2803022162 cites W1939709739 @default.
- W2803022162 cites W2021988356 @default.
- W2803022162 cites W2022213430 @default.
- W2803022162 cites W2026711372 @default.
- W2803022162 cites W2039479642 @default.
- W2803022162 cites W2075300336 @default.
- W2803022162 cites W2079914859 @default.
- W2803022162 cites W2098379879 @default.
- W2803022162 cites W2108302885 @default.
- W2803022162 cites W2109237866 @default.
- W2803022162 cites W2110662561 @default.
- W2803022162 cites W2114584281 @default.
- W2803022162 cites W2126983369 @default.
- W2803022162 cites W2134171514 @default.
- W2803022162 cites W2136489673 @default.
- W2803022162 cites W2139500303 @default.
- W2803022162 cites W2142742490 @default.
- W2803022162 cites W2150120272 @default.
- W2803022162 cites W2167591034 @default.
- W2803022162 cites W2192872568 @default.
- W2803022162 cites W2206432491 @default.
- W2803022162 cites W2274046219 @default.
- W2803022162 cites W2294000258 @default.
- W2803022162 cites W2465022801 @default.
- W2803022162 cites W2468950988 @default.
- W2803022162 cites W2507782211 @default.
- W2803022162 cites W2599426398 @default.
- W2803022162 cites W2602321390 @default.
- W2803022162 cites W2617909584 @default.
- W2803022162 cites W2619962134 @default.
- W2803022162 cites W2736162298 @default.
- W2803022162 cites W3140754719 @default.
- W2803022162 cites W4252135493 @default.
- W2803022162 doi "https://doi.org/10.1186/s13075-018-1567-2" @default.
- W2803022162 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5894179" @default.
- W2803022162 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29636109" @default.
- W2803022162 hasPublicationYear "2018" @default.
- W2803022162 type Work @default.
- W2803022162 sameAs 2803022162 @default.
- W2803022162 citedByCount "53" @default.
- W2803022162 countsByYear W28030221622018 @default.
- W2803022162 countsByYear W28030221622019 @default.
- W2803022162 countsByYear W28030221622020 @default.
- W2803022162 countsByYear W28030221622021 @default.
- W2803022162 countsByYear W28030221622022 @default.
- W2803022162 countsByYear W28030221622023 @default.
- W2803022162 crossrefType "journal-article" @default.
- W2803022162 hasAuthorship W2803022162A5012208859 @default.
- W2803022162 hasAuthorship W2803022162A5016622484 @default.
- W2803022162 hasAuthorship W2803022162A5024232551 @default.
- W2803022162 hasAuthorship W2803022162A5026841517 @default.
- W2803022162 hasAuthorship W2803022162A5027079857 @default.
- W2803022162 hasAuthorship W2803022162A5034806661 @default.
- W2803022162 hasAuthorship W2803022162A5048663075 @default.
- W2803022162 hasAuthorship W2803022162A5058333204 @default.
- W2803022162 hasAuthorship W2803022162A5073523669 @default.
- W2803022162 hasAuthorship W2803022162A5082138222 @default.
- W2803022162 hasAuthorship W2803022162A5090435133 @default.
- W2803022162 hasBestOaLocation W28030221621 @default.
- W2803022162 hasConcept C126322002 @default.
- W2803022162 hasConcept C141071460 @default.
- W2803022162 hasConcept C146357865 @default.
- W2803022162 hasConcept C151730666 @default.
- W2803022162 hasConcept C188816634 @default.
- W2803022162 hasConcept C71924100 @default.
- W2803022162 hasConcept C72563966 @default.
- W2803022162 hasConcept C86803240 @default.
- W2803022162 hasConcept C90924648 @default.
- W2803022162 hasConceptScore W2803022162C126322002 @default.
- W2803022162 hasConceptScore W2803022162C141071460 @default.
- W2803022162 hasConceptScore W2803022162C146357865 @default.
- W2803022162 hasConceptScore W2803022162C151730666 @default.
- W2803022162 hasConceptScore W2803022162C188816634 @default.
- W2803022162 hasConceptScore W2803022162C71924100 @default.
- W2803022162 hasConceptScore W2803022162C72563966 @default.
- W2803022162 hasConceptScore W2803022162C86803240 @default.
- W2803022162 hasConceptScore W2803022162C90924648 @default.
- W2803022162 hasFunder F4320321001 @default.
- W2803022162 hasIssue "1" @default.
- W2803022162 hasLocation W28030221621 @default.
- W2803022162 hasLocation W28030221622 @default.