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• W2803078341 abstract "MicroRNAs (miRNAs) are small noncoding RNAs that target mRNA to reduce gene and protein expression by repressing their targets' translation or inducing mRNA degradation. They play fundamental roles in various cancers, including prostate cancer. Each single miRNA may regulate hundreds of genes, and a certain gene may serve as a target by multiple miRNAs. Hence, miRNAs modulate, cell cycle, apoptosis, epithelial-mesenchymal transition (EMT), and metastasis, etc. In this review, we will summarize the several miRNAs that may function as oncogenes and tumor suppressors. And we will describe the each miRNAs associated with cell cycle, apoptosis, EMT, and metastasis in prostate cancer. Key Words: Prostatic neoplasms; MicroRNAs; Carcinogenesis." @default.
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• W2803078341 date "2018-04-30" @default.
• W2803078341 modified "2023-09-26" @default.
• W2803078341 title "The Role of MicroRNAs in Oncogenesis and Progression of Prostate Cancer" @default.
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• W2803078341 doi "https://doi.org/10.22465/kjuo.2018.16.1.1" @default.
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