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- W2803128840 abstract "Objective: To study the association of peripheral and central presbyacusis with cardiovascular and dementia risk scores (RSs), in an elderly population. Background: RSs are used to predict vascular and cognitive outcomes. There are no studies investigating the relationship between RSs and age-related hearing impairment. Design/Methods: Subjects enrolled in the Great AGE study, a population based study on aging in subjects 65+ (Castellana Grotte, Southern Italy) underwent multidisciplinary assessment including neurological, neuropsychological, geriatric and otolaryngology examinations. Information about vascular and other risk factors were collected in a structured interview. Mild cognitive impairment (MCI) was diagnosed according to Petersen criteria; peripheral and central presbycusis according to Gates criteria. Two risk scores were considered: the Reitz RS, a late-life RS for the 4-year prediction of dementia; the Framingham general RS largely used for the 10-year prediction of cardiovascular events, but also proposed to predict dementia. Results: In a sample of 947 individuals (530 males, 417 females; median age 73 years, range 65–92), 36.1% were in the high-risk categories using the Reits RS and 27.8%, using the Framingham RS. The Retz RS was associated with the presence of MCI (p Conclusions: The association between high vascular and dementia RS with cognitive impairment and central presbycusis may indicate that cognitive impairment and central presbycusis share the same pathogenic mechanism. Disclosure: Dr. Tortelli has nothing to disclose. Dr. Piccininni has nothing to disclose. Dr. Battista has nothing to disclose. Dr. Di Lena has nothing to disclose. Dr. Abbrescia has nothing to disclose. Dr. Barulli has nothing to disclose. Dr. Capozzo has nothing to disclose. Dr. Coppola has nothing to disclose. Dr. Lozupone has nothing to disclose. Dr. Panza has nothing to disclose. Dr. Sardone has nothing to disclose. Dr. Quaranta has nothing to disclose. Dr. Logroscino has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Lilly." @default.
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- W2803128840 date "2018-04-10" @default.
- W2803128840 modified "2023-09-23" @default.
- W2803128840 title "Dementia and vascular risk scores in an aging population: an association with cognitive and sensory impairment (P1.194)" @default.
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