FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2803156670> ?p ?o ?g. }

• W2803156670 abstract "Abstract Focused ultrasound combined with bubble-based agents serves as a non-invasive way to open the blood-brain barrier (BBB). Passive acoustic detection was well studied recently to monitor the acoustic emissions induced by the bubbles under ultrasound energy, but the ability to perform reliable BBB opening with a real-time feedback control algorithm has not been fully evaluated. This study focuses on characterizing the acoustic emissions of different types of bubbles: Optison, Definity, and a custom-made nanobubble. Their performance on reliable BBB opening under real-time feedback control based on acoustic detection was evaluated both in-vitro and in-vivo . The experiments were conducted using a 0.5 MHz focused ultrasound transducer with in-vivo focal pressure ranges from 0.1–0.7 MPa. Successful feedback control was achieved with all three agents when combining with infusion injection. Localized opening was confirmed with Evans blue dye leakage. Microscopic images were acquired to review the opening effects. Under similar total gas volume, nanobubble showed a more reliable opening effect compared to Optison and Definity (p < 0.05). The conclusions obtained from this study confirm the possibilities of performing stable opening using a feedback control algorithm combined with infusion injection. It also opens another potential research area of BBB opening using sub-micron bubbles." @default.
• W2803156670 created "2018-06-01" @default.
• W2803156670 creator A5003155728 @default.
• W2803156670 creator A5005964601 @default.
• W2803156670 creator A5007169954 @default.
• W2803156670 creator A5009662027 @default.
• W2803156670 creator A5023307128 @default.
• W2803156670 creator A5041840229 @default.
• W2803156670 creator A5043549995 @default.
• W2803156670 creator A5058817270 @default.
• W2803156670 creator A5071617413 @default.
• W2803156670 creator A5083925535 @default.
• W2803156670 creator A5091103809 @default.
• W2803156670 date "2018-05-22" @default.
• W2803156670 modified "2023-10-18" @default.
• W2803156670 title "Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control" @default.
• W2803156670 cites W1801991441 @default.
• W2803156670 cites W1970683344 @default.
• W2803156670 cites W1977963509 @default.
• W2803156670 cites W1981449179 @default.
• W2803156670 cites W1994515076 @default.
• W2803156670 cites W2003331591 @default.
• W2803156670 cites W2003736464 @default.
• W2803156670 cites W2007457253 @default.
• W2803156670 cites W2010234990 @default.
• W2803156670 cites W2019982556 @default.
• W2803156670 cites W2020531776 @default.
• W2803156670 cites W2026988376 @default.
• W2803156670 cites W2029646789 @default.
• W2803156670 cites W2030106926 @default.
• W2803156670 cites W2039557128 @default.
• W2803156670 cites W2043922378 @default.
• W2803156670 cites W2045053892 @default.
• W2803156670 cites W2046595046 @default.
• W2803156670 cites W2055492146 @default.
• W2803156670 cites W2056416291 @default.
• W2803156670 cites W2063909850 @default.
• W2803156670 cites W2068597696 @default.
• W2803156670 cites W2074523012 @default.
• W2803156670 cites W2079022594 @default.
• W2803156670 cites W2082319347 @default.
• W2803156670 cites W2083253967 @default.
• W2803156670 cites W2084355055 @default.
• W2803156670 cites W2087043566 @default.
• W2803156670 cites W2087830691 @default.
• W2803156670 cites W2092920458 @default.
• W2803156670 cites W2094453116 @default.
• W2803156670 cites W2094514360 @default.
• W2803156670 cites W2094621092 @default.
• W2803156670 cites W2097806437 @default.
• W2803156670 cites W2098741244 @default.
• W2803156670 cites W2103225095 @default.
• W2803156670 cites W2107758958 @default.
• W2803156670 cites W2108277337 @default.
• W2803156670 cites W2110171702 @default.
• W2803156670 cites W2114596635 @default.
• W2803156670 cites W2115362657 @default.
• W2803156670 cites W2115764559 @default.
• W2803156670 cites W2128610705 @default.
• W2803156670 cites W2131358222 @default.
• W2803156670 cites W2132849766 @default.
• W2803156670 cites W2144658958 @default.
• W2803156670 cites W2144686091 @default.
• W2803156670 cites W2152233647 @default.
• W2803156670 cites W2154096369 @default.
• W2803156670 cites W2156360500 @default.
• W2803156670 cites W2166980283 @default.
• W2803156670 cites W2203865302 @default.
• W2803156670 cites W2205597722 @default.
• W2803156670 cites W2223036396 @default.
• W2803156670 cites W2317612767 @default.
• W2803156670 cites W2607182593 @default.
• W2803156670 cites W4248384838 @default.
• W2803156670 cites W4254442929 @default.
• W2803156670 doi "https://doi.org/10.1038/s41598-018-26330-7" @default.
• W2803156670 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5964106" @default.
• W2803156670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29789589" @default.
• W2803156670 hasPublicationYear "2018" @default.
• W2803156670 type Work @default.
• W2803156670 sameAs 2803156670 @default.
• W2803156670 citedByCount "65" @default.
• W2803156670 countsByYear W28031566702019 @default.
• W2803156670 countsByYear W28031566702020 @default.
• W2803156670 countsByYear W28031566702021 @default.
• W2803156670 countsByYear W28031566702022 @default.
• W2803156670 countsByYear W28031566702023 @default.
• W2803156670 crossrefType "journal-article" @default.
• W2803156670 hasAuthorship W2803156670A5003155728 @default.
• W2803156670 hasAuthorship W2803156670A5005964601 @default.
• W2803156670 hasAuthorship W2803156670A5007169954 @default.
• W2803156670 hasAuthorship W2803156670A5009662027 @default.
• W2803156670 hasAuthorship W2803156670A5023307128 @default.
• W2803156670 hasAuthorship W2803156670A5041840229 @default.
• W2803156670 hasAuthorship W2803156670A5043549995 @default.
• W2803156670 hasAuthorship W2803156670A5058817270 @default.
• W2803156670 hasAuthorship W2803156670A5071617413 @default.
• W2803156670 hasAuthorship W2803156670A5083925535 @default.
• W2803156670 hasAuthorship W2803156670A5091103809 @default.
• W2803156670 hasBestOaLocation W28031566701 @default.
• W2803156670 hasConcept C121332964 @default.

• next