FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2803243498> ?p ?o ?g. }

• W2803243498 abstract "Abstract Programmed cell death 1 ligand 1 (PD-L1) is a ligand of programmed cell death 1 (PD-1) that functions as an immune checkpoint by down-regulating immune responses. To determine whether PD-L1 is a therapy target in vitiligo treatment, Pmel-1 vitiligo mice were treated with a PD-L1 fusion protein. Treatment with this fusion protein significantly reversed/suppressed depigmentation development in adult Pmel-1 mice. Mechanistically, enrichment of regulatory T cells (Treg) in the skin was detected after PD-L1 fusion protein treatment in Pmel-1 mice. Furthermore, Tregs abundance was also increased in both the spleen and circulation of Pmel-1 mice treated with PD-L1. These data indicate that PD-L1 protein therapy inhibits the immune response and reverses depigmentation development in Pmel-1 vitiligo mice." @default.
• W2803243498 created "2018-06-01" @default.
• W2803243498 creator A5004780696 @default.
• W2803243498 creator A5010479652 @default.
• W2803243498 creator A5022526821 @default.
• W2803243498 creator A5030127076 @default.
• W2803243498 creator A5046587422 @default.
• W2803243498 creator A5050134236 @default.
• W2803243498 creator A5067989213 @default.
• W2803243498 creator A5076905446 @default.
• W2803243498 date "2018-01-25" @default.
• W2803243498 modified "2023-10-18" @default.
• W2803243498 title "PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin" @default.
• W2803243498 cites W1909576292 @default.
• W2803243498 cites W1980714287 @default.
• W2803243498 cites W2008413924 @default.
• W2803243498 cites W2042163461 @default.
• W2803243498 cites W2062549560 @default.
• W2803243498 cites W2064021186 @default.
• W2803243498 cites W2064376469 @default.
• W2803243498 cites W2064709295 @default.
• W2803243498 cites W2065684908 @default.
• W2803243498 cites W2069384112 @default.
• W2803243498 cites W2098772563 @default.
• W2803243498 cites W2103417557 @default.
• W2803243498 cites W2107752337 @default.
• W2803243498 cites W2118471749 @default.
• W2803243498 cites W2119662171 @default.
• W2803243498 cites W2124060252 @default.
• W2803243498 cites W2131136878 @default.
• W2803243498 cites W2137096190 @default.
• W2803243498 cites W2139070921 @default.
• W2803243498 cites W2145871366 @default.
• W2803243498 cites W2155464214 @default.
• W2803243498 cites W2254039939 @default.
• W2803243498 cites W2343144688 @default.
• W2803243498 doi "https://doi.org/10.1038/s41598-018-19407-w" @default.
• W2803243498 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5785514" @default.
• W2803243498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29371688" @default.
• W2803243498 hasPublicationYear "2018" @default.
• W2803243498 type Work @default.
• W2803243498 sameAs 2803243498 @default.
• W2803243498 citedByCount "40" @default.
• W2803243498 countsByYear W28032434982018 @default.
• W2803243498 countsByYear W28032434982019 @default.
• W2803243498 countsByYear W28032434982020 @default.
• W2803243498 countsByYear W28032434982021 @default.
• W2803243498 countsByYear W28032434982022 @default.
• W2803243498 countsByYear W28032434982023 @default.
• W2803243498 crossrefType "journal-article" @default.
• W2803243498 hasAuthorship W2803243498A5004780696 @default.
• W2803243498 hasAuthorship W2803243498A5010479652 @default.
• W2803243498 hasAuthorship W2803243498A5022526821 @default.
• W2803243498 hasAuthorship W2803243498A5030127076 @default.
• W2803243498 hasAuthorship W2803243498A5046587422 @default.
• W2803243498 hasAuthorship W2803243498A5050134236 @default.
• W2803243498 hasAuthorship W2803243498A5067989213 @default.
• W2803243498 hasAuthorship W2803243498A5076905446 @default.
• W2803243498 hasBestOaLocation W28032434981 @default.
• W2803243498 hasConcept C104317684 @default.
• W2803243498 hasConcept C123894998 @default.
• W2803243498 hasConcept C16005928 @default.
• W2803243498 hasConcept C203014093 @default.
• W2803243498 hasConcept C2776972258 @default.
• W2803243498 hasConcept C2779179668 @default.
• W2803243498 hasConcept C2779980618 @default.
• W2803243498 hasConcept C2780931953 @default.
• W2803243498 hasConcept C40767141 @default.
• W2803243498 hasConcept C54355233 @default.
• W2803243498 hasConcept C71924100 @default.
• W2803243498 hasConcept C86803240 @default.
• W2803243498 hasConcept C8891405 @default.
• W2803243498 hasConceptScore W2803243498C104317684 @default.
• W2803243498 hasConceptScore W2803243498C123894998 @default.
• W2803243498 hasConceptScore W2803243498C16005928 @default.
• W2803243498 hasConceptScore W2803243498C203014093 @default.
• W2803243498 hasConceptScore W2803243498C2776972258 @default.
• W2803243498 hasConceptScore W2803243498C2779179668 @default.
• W2803243498 hasConceptScore W2803243498C2779980618 @default.
• W2803243498 hasConceptScore W2803243498C2780931953 @default.
• W2803243498 hasConceptScore W2803243498C40767141 @default.
• W2803243498 hasConceptScore W2803243498C54355233 @default.
• W2803243498 hasConceptScore W2803243498C71924100 @default.
• W2803243498 hasConceptScore W2803243498C86803240 @default.
• W2803243498 hasConceptScore W2803243498C8891405 @default.
• W2803243498 hasIssue "1" @default.
• W2803243498 hasLocation W28032434981 @default.
• W2803243498 hasLocation W28032434982 @default.
• W2803243498 hasLocation W28032434983 @default.
• W2803243498 hasLocation W28032434984 @default.
• W2803243498 hasOpenAccess W2803243498 @default.
• W2803243498 hasPrimaryLocation W28032434981 @default.
• W2803243498 hasRelatedWork W167449432 @default.
• W2803243498 hasRelatedWork W1966357729 @default.
• W2803243498 hasRelatedWork W2037980316 @default.
• W2803243498 hasRelatedWork W2066464304 @default.
• W2803243498 hasRelatedWork W2901970500 @default.
• W2803243498 hasRelatedWork W2904675130 @default.
• W2803243498 hasRelatedWork W2939274059 @default.
• W2803243498 hasRelatedWork W3198997433 @default.

• next