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- W2803255990 abstract "We evaluated the impact of structured surveillance using bioimpedance spectroscopy (BIS) to reduce the rate of chronic breast cancer-related lymphedema (BCRL) in high-risk patients undergoing axillary lymph node dissection (ALND).From April 2010 through November 2016, 93 patients who underwent ALND were prospectively monitored with BIS using L-Dex. Intervention for an L-Dex increase of >10 consisted of applying an over the counter (OTC) sleeve followed by re-evaluation after 4 weeks. The utilization of complex decongestive physiotherapy (CDP) represented a surrogate for chronic BCRL.Median follow-up was 24 months. 55% of patients received taxane-based chemotherapy, 24% received some form of axillary irradiation (includes additional fields or high tangents) and 66% had an elevated body mass index (BMI) with the median number of nodes removed being 19. Overall, 75% of these patients had at least one additional high-risk feature (taxane chemotherapy, axillary radiation, elevated BMI), 48% had at least two, and 6% had all. Thirty-three patients (35.4%) developed an elevated L-Dex score with only 10 (10.8%) requiring CDP (30.3% of those undergoing treatment with sleeve). At last follow-up, only three patients (3%) had unresolved BCRL.The results of this analysis support previous data regarding prospective BCRL surveillance and early intervention using BIS. With this approach, only 3% of patients have chronic BCRL." @default.
- W2803255990 created "2018-06-01" @default.
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- W2803255990 date "2018-06-12" @default.
- W2803255990 modified "2023-10-16" @default.
- W2803255990 title "Preventing Breast Cancer-Related Lymphedema in High-Risk Patients: The Impact of a Structured Surveillance Protocol Using Bioimpedance Spectroscopy" @default.
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- W2803255990 doi "https://doi.org/10.3389/fonc.2018.00197" @default.
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