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• W2803642665 abstract "Markov jump process models have many applications across science. Often these models are defined on a state space of product form and only one of the components of the process is of direct interest. In this paper we extend the marginal process framework, which provides a marginal description of the component of interest, to the case of fully coupled processes. We use entropic matching to obtain a finite-dimensional approximation of the filtering equation, which governs the transition rates of the marginal process. The resulting equations can be seen as a combination of two projection operations applied to the full master equation so that we obtain a principled model reduction framework. We demonstrate the resulting reduced description on the totally asymmetric exclusion process. An important class of Markov jump processes are stochastic reaction networks, which have applications in chemical and biomolecular kinetics, ecological models, and models of social networks. We obtain a particularly simple instantiation of the marginal process framework for mass-action systems by using product Poisson distributions for the approximate solution of the filtering equation. We investigate the resulting approximate marginal process analytically and numerically." @default.
• W2803642665 created "2018-06-01" @default.
• W2803642665 creator A5058657039 @default.
• W2803642665 creator A5070544702 @default.
• W2803642665 date "2018-06-26" @default.
• W2803642665 modified "2023-10-03" @default.
• W2803642665 title "Marginal process framework: A model reduction tool for Markov jump processes" @default.
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• W2803642665 doi "https://doi.org/10.1103/physreve.97.062147" @default.
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• W2803642665 hasPublicationYear "2018" @default.
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