Matches in SemOpenAlex for { <https://semopenalex.org/work/W2803670136> ?p ?o ?g. }
- W2803670136 abstract "Gestational diabetes mellitus (GDM) has serious consequences such as increased risks of preeclampsia, macrosomia and cesarean delivery. Even though the mechanistic basis of GDM has not been completely understood, several risk factors have been identified and one of these is vitamin D. However, the link between vitamin D deficiency and development of GDM is yet to be proven with certainty.This study aimed to investigate the link between the incidence of GDM and serum vitamin D level in pregnant women of Saudi Arabia. 515 Saudi women (ages 18-46) in their 24-28th week of pregnancy, visiting various hospitals of Riyadh, participated in this study. Serum vitamin D and various biochemical and anthropometric parameters were determined in the first trimester and the recruits were screened for GDM by OGTT according to IADPSG criteria in their 2nd trimester. The association between vitamin D deficiency and development of GDM was calculated based on odds ratio of the incidence of GDM among vitamin D deficient and normal women.In this study cohort of 515 pregnant women, in the first trimester vitamin D deficiency (< 50 nmol/l) was detected in 425 (82.5%). On their 2nd visit (2nd trimester), 116 (27.7%) were diagnosed with GDM out of 419 with OGTT, according to IADPSG criteria. GDM risk was significantly higher among vitamin D deficient than non-deficient women (Odds Ratio: 2.87; Confidence Interval: 1.32-6.25; P = 0.008) even after adjusting for season, sun exposure and vitamin D intake (OR: 2.9; CI: 1.07-7.89). Of the various anthropometric and biochemical parameters, the GDM women differed significantly from non-GDM women with respect to serum levels of triglycerides (in mmol/l) (1.3 ± 0.6; 1.5 ± 0.6, p = 0.018) and fasting glucose (in mmol/l) [4.7 (4.3-5.2); 5.1 (4.6-5.6), p < 0.01]. Also, fasting glucose level in the 2nd trimester correlated inversely to serum vitamin D level determined during the 1st trimester (r = - 0.121; p = 0.014).Results of our study reveal a significantly higher risk of development of GDM among pregnant women having deficient vitamin D status." @default.
- W2803670136 created "2018-06-01" @default.
- W2803670136 creator A5004378510 @default.
- W2803670136 creator A5007592867 @default.
- W2803670136 creator A5024001395 @default.
- W2803670136 creator A5031005278 @default.
- W2803670136 creator A5034440094 @default.
- W2803670136 creator A5037372675 @default.
- W2803670136 creator A5046686427 @default.
- W2803670136 creator A5049717712 @default.
- W2803670136 creator A5062732378 @default.
- W2803670136 creator A5063194725 @default.
- W2803670136 creator A5072234088 @default.
- W2803670136 creator A5079459526 @default.
- W2803670136 creator A5082380442 @default.
- W2803670136 creator A5089773768 @default.
- W2803670136 creator A5091554971 @default.
- W2803670136 date "2018-04-10" @default.
- W2803670136 modified "2023-10-18" @default.
- W2803670136 title "Lower vitamin D levels in Saudi pregnant women are associated with higher risk of developing GDM" @default.
- W2803670136 cites W1570984620 @default.
- W2803670136 cites W1603962903 @default.
- W2803670136 cites W1801556460 @default.
- W2803670136 cites W1927620910 @default.
- W2803670136 cites W1977007818 @default.
- W2803670136 cites W1979136992 @default.
- W2803670136 cites W1983305453 @default.
- W2803670136 cites W1983313567 @default.
- W2803670136 cites W1987930442 @default.
- W2803670136 cites W1988182228 @default.
- W2803670136 cites W1996753977 @default.
- W2803670136 cites W2009872849 @default.
- W2803670136 cites W2011572647 @default.
- W2803670136 cites W2012357574 @default.
- W2803670136 cites W2027867395 @default.
- W2803670136 cites W2034302593 @default.
- W2803670136 cites W2035514750 @default.
- W2803670136 cites W2045651982 @default.
- W2803670136 cites W2067687117 @default.
- W2803670136 cites W2089290815 @default.
- W2803670136 cites W2089668510 @default.
- W2803670136 cites W2097131477 @default.
- W2803670136 cites W2117085608 @default.
- W2803670136 cites W2131946475 @default.
- W2803670136 cites W2140694890 @default.
- W2803670136 cites W2145798427 @default.
- W2803670136 cites W2164347728 @default.
- W2803670136 cites W2189054832 @default.
- W2803670136 cites W2216402574 @default.
- W2803670136 cites W2264672668 @default.
- W2803670136 cites W2313686490 @default.
- W2803670136 cites W2317043505 @default.
- W2803670136 cites W2339824791 @default.
- W2803670136 cites W2347083470 @default.
- W2803670136 cites W2525914234 @default.
- W2803670136 cites W2561522093 @default.
- W2803670136 cites W2563476603 @default.
- W2803670136 cites W274973038 @default.
- W2803670136 doi "https://doi.org/10.1186/s12884-018-1723-3" @default.
- W2803670136 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5891955" @default.
- W2803670136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29631547" @default.
- W2803670136 hasPublicationYear "2018" @default.
- W2803670136 type Work @default.
- W2803670136 sameAs 2803670136 @default.
- W2803670136 citedByCount "37" @default.
- W2803670136 countsByYear W28036701362018 @default.
- W2803670136 countsByYear W28036701362019 @default.
- W2803670136 countsByYear W28036701362020 @default.
- W2803670136 countsByYear W28036701362021 @default.
- W2803670136 countsByYear W28036701362022 @default.
- W2803670136 countsByYear W28036701362023 @default.
- W2803670136 crossrefType "journal-article" @default.
- W2803670136 hasAuthorship W2803670136A5004378510 @default.
- W2803670136 hasAuthorship W2803670136A5007592867 @default.
- W2803670136 hasAuthorship W2803670136A5024001395 @default.
- W2803670136 hasAuthorship W2803670136A5031005278 @default.
- W2803670136 hasAuthorship W2803670136A5034440094 @default.
- W2803670136 hasAuthorship W2803670136A5037372675 @default.
- W2803670136 hasAuthorship W2803670136A5046686427 @default.
- W2803670136 hasAuthorship W2803670136A5049717712 @default.
- W2803670136 hasAuthorship W2803670136A5062732378 @default.
- W2803670136 hasAuthorship W2803670136A5063194725 @default.
- W2803670136 hasAuthorship W2803670136A5072234088 @default.
- W2803670136 hasAuthorship W2803670136A5079459526 @default.
- W2803670136 hasAuthorship W2803670136A5082380442 @default.
- W2803670136 hasAuthorship W2803670136A5089773768 @default.
- W2803670136 hasAuthorship W2803670136A5091554971 @default.
- W2803670136 hasBestOaLocation W28036701361 @default.
- W2803670136 hasConcept C120665830 @default.
- W2803670136 hasConcept C121332964 @default.
- W2803670136 hasConcept C124490489 @default.
- W2803670136 hasConcept C126322002 @default.
- W2803670136 hasConcept C131872663 @default.
- W2803670136 hasConcept C134018914 @default.
- W2803670136 hasConcept C156957248 @default.
- W2803670136 hasConcept C207103383 @default.
- W2803670136 hasConcept C2777218350 @default.
- W2803670136 hasConcept C2779234561 @default.
- W2803670136 hasConcept C2779434492 @default.
- W2803670136 hasConcept C2779740938 @default.