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- W2803703149 abstract "Anthracyclines are effective agents generally used to treat solid-tumor malignancies and hematologic malignancies. The widely use of anthracyclines for over 40 years has quite improved cancer survival statistics. Nevertheless, clinical utility is restricted by dose-dependent cardiotoxicity that adversely affects 10%-30% of patients. Anthracyclines-induced cardiotoxicity may be sorted as acute/subacute or chronic/late toxicity, becoming a devastating adverse effect resulting in poor quality of life, morbidity, and premature mortality. Traditional Chinese Medicine, has a history of over 2,000 years, with both unique theories and ample experience. Several studies have researched the potential of natural products in decreasing the cardiotoxicity effects of chemotherapeutic agents on healthy cells, while unaffected their antineoplastic activity. This article discusses the mechanism of anthracyclines-induced cardiotoxicity, and summarizes traditional Chinese medicine treatment on anthracyclines-induced heart failure (HF), cardiac arrhythmia, cardiomyopathy, and myocardial ischemia Chinesein recent years, in order to provide a reference for clinical prevention and treatment of cardiac toxicity." @default.
- W2803703149 created "2018-06-01" @default.
- W2803703149 creator A5002577443 @default.
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- W2803703149 creator A5044914605 @default.
- W2803703149 creator A5087161473 @default.
- W2803703149 date "2018-05-15" @default.
- W2803703149 modified "2023-09-26" @default.
- W2803703149 title "A Review on the Effect of Traditional Chinese Medicine Against Anthracycline-Induced Cardiac Toxicity" @default.
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